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5-Aminolevulinic acid phosphate (ALA) moetsi oa phofo CAS No.: 868074-65-1 98% bohloeki min. ka Theko e Ntle

Tlhaloso e Khutšoanyane:

5-Aminolevulinic acid phosphate(5-ALA), amino acid ea tlhaho, ke ntho e sebetsang e teng ka ho pharaletseng bophelong. 5-Aminolevulinic acid phosphate (5-ALA phosphate) e tsoa ho 5-ALA, e leng bonolo ho kenngoa le ho sebelisoa ke 'mele oa motho.


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Lebitso la sehlahisoa

5-Aminolevulinic acid phosphate

Lebitso le leng

5-amino-4-oxopentanoic acid, phosphoric acid; 5-aminolevulinic acid phosphate, 5-ALA phosphate; 5-Amino-4-oxopentanoic acid phosphate;

5-Aminolevulinic acid phosphate;

Pentanoic acid, 5-amino-4-oxo-, phosphate

Nomoro ea CAS.

868074-65-1

Mokhoa oa limolek'hule

C5H12NO7P

Boima ba molek'hule

229.13

Bohloeki

98.0%

Ponahalo

Phofo e tšoeu ho isa ho e tšoeu

Kopo

Tlatsetso ea Lijo tse tala

Kenyelletso ea sehlahisoa

5-Aminolevulinic acid phosphate, eo hangata e tsejoang e le ALA phosphate, ke senotlolo sa bohareng ba biosynthesis ea heme, karolo ea bohlokoa ea hemoglobin, myoglobin le li-enzyme tse sa tšoaneng 'meleng. ALA phosphate e entsoe ka letoto la karabelo ea enzymatic e hlahang haholo ho mitochondria, liteishene tsa matla tsa lisele tsa rona. E thehiloe ho tsoa ho condensation ea glycine le succinyl-CoA, e leng likarolo tsa bohlokoa tsa litsela tsa rona tsa metabolic. Tšimoloho ea heme e bohlokoa bophelong ba motho kaha molek'hule ena e phetha karolo ea bohlokoa ho tsamaisa oksijene, ho fetisetsa elektronike le ho tlosa chefo. ALA phosphate ke mohato o fokotsang sekhahla ho heme biosynthesis. Ka letoto la liphetoho tsa enzymatic, ALA phosphate e fetoloa porphobilinogen, molek'hule ea pele ea heme.

Sebopeho

(1) Bohloeki bo phahameng: 5-aminolevulinic acid phosphate e ka fumanoa e le lihlahisoa tse hloekileng ka mekhoa e hloekisitsoeng ea tlhahiso. Bohloeki bo phahameng bo bolela bioavailability e betere le ho fokotseha ho hoholo ha maikutlo.

(2) Tšireletseho: 5-aminolevulinic acid phosphate e 'nile ea pakoa e sireletsehile bakeng sa' mele oa motho.

(3) Botsitso: 5-Aminolevulinic acid phosphate e na le botsitso bo botle 'me e ka boloka mosebetsi oa eona le phello tlas'a maemo a sa tšoaneng le maemo a polokelo.

Lisebelisoa

5-Aminolevulinic acid phosphate (5-ALA) ke amino acid ea tlhaho le ntho e sebetsang e teng haholo bophelong. Ke selelekela sa metsoako ea porphyrin le substrate bakeng sa karabelo ea biochemical ea chlorophyll, heme le vithamine B12. 5-ALA phosphate e tsoa ho 5-ALA 'me e kenngoa habonolo le ho sebelisoa ke' mele. Tsamaiso ea molomo ea 5-ALA phosphate e ka kenya tšebetsong myoglobin synthase, ea potlakisa motsoako oa myoglobin 'meleng oa motho, ea eketsa mafura a mesifa le ho fokotsa mafura. Ntle le moo, 5-ALA e ka boela ea ntlafatsa ts'ebetso ea mitochondria liseleng tsa motho, ea khothaletsa metabolism, ea ntlafatsa ts'ebetso ea ho fumana matla, le ho fokotsa tsoekere ea mali le lipids tsa mali. Qetellong, 5-ALA phosphate e molemo haholo ho bophelo bo botle.


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