J-147 moetsi oa phofo CAS No.: 1146963-51-0 99.0% bohloeki min. bakeng sa lisebelisoa tsa tlatsetso
Lihlahisoa tsa lihlahisoa
| Lebitso la sehlahisoa | 2,2,2-Trifluoroacetic acid 1-(2,4-DiMethylphenyl)-2-[(3-Methoxyphenyl)Methylene]hydrazide] |
| Lebitso le leng | J-147, J147 |
| Nomoro ea CAS. | 1146963-51-0 |
| Mokhoa oa limolek'hule | C18H17F3N2O2 |
| Boima ba molek'hule | 350.33 |
| Bohloeki | 99% |
| Ponahalo | Phofo e tšoeu |
| Ho paka | 1kg ka mokotla |
| Kopo | lithethefatsi tsa nootropic |
Kenyelletso ea Sehlahisoa
J-147 ke neuroprotectant e matla ka ho khetheha e sebetsang ka molomo e nkiloeng haholo-holo ho curcumin, motsoako o sebetsang oa turmeric. Ho fapana le curcumin, e tšela mokoallo oa mali-boko ka katleho haholo. Har'a bona, J-147 e sebetsa ka ho tlama ho ATP synthase. Tlhahiso e feteletseng ea ATP e amahanngoa le mokhoa oa ho tsofala. Ntle le ho eketseha ha maemo a li-neurotransmitters NGF le BDNF, J-147 e ka laola sena. Ntle le moo, J-147 e thibela monoamine oxidase B le dopamine transporter. E khothalletsa ho hola ha boko ka ho eketsa maemo a methapo ea kutlo (NGF) le neurotrophic factor (BDNF) e tsoang bokong. Habohlokoa le ho feta, J-147 e ka khothaletsa kholo ea lisele tse ncha tsa methapo, ea ntlafatsa bokhoni ba boko ba ho ithuta le mohopolo, le ho ntlafatsa ts'ebetso ea kelello.
Sebopeho
(1) Bohloeki bo phahameng: J-147 e ka fumana lihlahisoa tse hloekileng ka ho hloekisa mekhoa ea tlhahiso. Bohloeki bo phahameng bo bolela bioavailability e betere le ho fokotseha ho hoholo ha maikutlo.
(2) Tšireletseho: J-147 e pakiloe e sireletsehile bakeng sa ’mele oa motho.
(3) Botsitso: J-147 e na le botsitso bo botle 'me e ka boloka ts'ebetso ea eona le phello tlas'a maemo a sa tšoaneng le maemo a polokelo.
(4) Ho bonolo ho monya: J-147 e ka monngoa ka potlako ke ’mele oa motho, e kenella potolohong ea mali ka maleng, ’me e abeloa lisele le litho tse sa tšoaneng.
Lisebelisoa
J-147 ke motsoako oa maiketsetso oo mokhoa oa oona o ka sehloohong oa ts'ebetso o kenyelletsang ntlafatso ea mitochondrial, ka tsela eo e ntlafatsa tlhahiso ea matla boemong ba lisele. J-147 e etselitsoe ho ntlafatsa bokhoni ba boko ba ho itokisa le ho itšireletsa tšenyo e amanang le lilemo ka ho ntlafatsa tšebetso ea mitochondrial. Ho feta moo, J-147 e bonts'a thepa ea bohlokoa e khahlanong le ho ruruha le antioxidant, e ntlafatsang le ho feta litlamorao tse ka bang teng tsa neuroprotective. J-147 e ka khothaletsa kholo ea lisele tse ncha tsa methapo, ea ntlafatsa bokhoni ba boko ba ho ithuta le mohopolo, le ho ntlafatsa ts'ebetso ea kelello.
