Bophelong ba rōna ba letsatsi le letsatsi bo maphathaphathe, ho tloaelehile hore nako le nako re ikutloe re imetsoe kelellong, re tšoenyehile, esita le ho hlonama. Maikutlo ana a ka senya bophelo ba rona ba kelello, hangata a re siea re batla litsela tsa ho phahamisa moea. Le hoja ho na le litsela tse ngata tsa ho ntlafatsa maikutlo a rōna, ntlha ea bohlokoa eo re lokelang ho nahana ka eona ke neurotransmitter, serotonin. Hangata e bitsoa "homone ea ho ikutloa hantle," serotonin e phetha karolo ea bohlokoa ho laola maikutlo a rona, mehopolo le bophelo bo botle ka kakaretso.
Joale, serotonin ke eng? Serotonin, e tsejoang hape e le serotonin, ke k'hemik'hale e sebetsang joalo ka neurotransmitter, ho bolelang hore e sebetsa joalo ka lenģosa le tsamaisang melaetsa pakeng tsa lisele tsa methapo bokong. Haholo-holo e hlahisoa bokong ba boko, empa hape e fumaneha likarolong tse ling tsa 'mele, joalo ka mala. Hangata e bitsoa “hormone ea thabo” kapa “molek’hule ea thabo” hobane e amahanngoa le maikutlo a thabo, khotsofalo le boiketlo.
Hang ha serotonin e hlahisoa, e lokolloa ho li-synapse, kapa likheo pakeng tsa lisele tsa methapo. Joale e tlama ho li-receptor tse itseng holim'a lisele tsa methapo e haufi. Ts'ebetso ena e tlamang e nolofalletsa puisano lipakeng tsa lisele le ho thusa ho fetisa melaetsa.
Serotonin e bapala karolo ea bohlokoa ho laolang mesebetsi e fapaneng 'meleng ea rona, ho kenyelletsa boroko, takatso ea lijo, tšilo ea lijo le mohopolo. E ameha taolong ea maikutlo a rona mme e thusa ho boloka maikutlo a tsitsitseng. Maemo a serotonin bokong ba rona a ka ama bophelo ba rona ba kelello haholo.
Serotonin ha e ame bophelo ba rona ba maikutlo le kelello feela, empa e boetse e phetha karolo ea bohlokoa bophelong ba rona ba 'mele. Serotonin e laola nako ea rona ea ho robala le boleng ba boroko ka kakaretso. Tekanyo e lekaneng ea serotonin bokong e khothalletsa boroko bo khathollang, ha maemo a tlaase a ka baka mathata a ho robala a kang ho hlobaela.
Serotonin ke neurotransmitter bokong e ikarabellang bakeng sa ho laola maikutlo, maikutlo le boroko. Hangata e bitsoa lik'hemik'hale tsa "ho ikutloa hantle" hobane e thusa ho tlisa boikutlo ba boiketlo. Serotonin e phetha karolo ea bohlokoa ho boloka ho leka-lekana bokong, 'me tšitiso leha e le efe ea maemo a eona e ka baka mathata a sa tšoaneng a bophelo bo botle ba kelello, ho akarelletsa le ho tšoenyeha.
Lipatlisiso li fumane hore batho ba nang le mathata a ho tšoenyeha ba atisa ho ba le maemo a sa tsitsang a serotonin bokong ba bona. Maemo a tlase a serotonin a 'nile a amahanngoa le kotsi e eketsehileng ea mathata a ho tšoenyeha, kaha serotonin e thusa ho laola maikutlo le matšoenyeho. Ha maemo a serotonin a le tlase, batho ba ka 'na ba e-ba le matšoao a kang ho teneha, ho hloka botsitso le ho tšoenyeha ho hoholo.
Selectional serotonin reuptake inhibitors (SSRIs) ke lithethefatsi tse thibelang ho tepella maikutlo tse atisang ho sebelisoa ho phekola batho ba nang le mathata a ho tšoenyeha. Lithethefatsi tsena li sebetsa ka ho eketsa maemo a serotonin bokong. Ka ho etsa joalo, li-SSRI li thusa ho tsosolosa tekanyo ea serotonin le ho fokotsa matšoao a ho tšoenyeha. Leha ho le joalo, ke habohlokoa ho hlokomela hore serotonin ke karolo e le 'ngoe feela ea litsela tse rarahaneng tsa methapo e amanang le mathata a ho tšoenyeha,' me lintlha tse ling tse kang liphatsa tsa lefutso, tikoloho le liphihlelo tsa bophelo le tsona li tlatsetsa ho nts'etsopele ea maemo ana.
Lipatlisiso li bontša hore ho ikoetlisa kamehla ho ka matlafatsa tlhahiso ea serotonin bokong. Boikoetliso ha bo khothalletse ho lokolloa ha serotonin feela, empa bo boetse bo eketsa kutlo ea boko ho neurotransmitter ena, ka hona ho ntlafatsa maikutlo le ho fokotsa matšoenyeho.
Ho feta moo, ho itloaetsa mekhoa ea ho laola khatello ea maikutlo joalo ka ho thuisa, boikoetliso bo tebileng ba ho phefumoloha, le ho ba le kelello ho ka thusa ho eketsa maemo a serotonin le ho fokotsa matšoao a ho tšoenyeha. Mekhoa ena e khothalletsa boikhathollo le khutso, e lumellang boko ho hlahisa le ho sebelisa serotonin ka katleho.
1. Maikutlo a phahameng le maikutlo a tsitsitseng
Serotonin e tsejoa ka bokhoni ba eona ba ho laola maikutlo. Ke mokhoa oa tlhaho oa ho tsitsisa maikutlo o khothalletsang boikutlo ba boiketlo le khotsofalo ha o ntse o fokotsa ho tšoenyeha le khatello ea kelello. Maemo a lekaneng a serotonin a bohlokoa ho thibela mathata a maikutlo a kang khatello ea maikutlo, matšoenyeho le lefu la ho ferekana kelellong. Ka ho eketsa maemo a serotonin, batho ka bomong ba ka ba le botsitso bo ntlafetseng ba maikutlo, boikutlo bo eketsehileng ba boiketlo ka kakaretso, le pono e nepahetseng haholoanyane ea bophelo.
2. Ntlafatsa ts'ebetso ea kelello
Ntle le litlamorao tsa eona maikutlong, serotonin e boetse e bapala karolo ea bohlokoa ts'ebetsong ea kelello. Li-neurotransmitter tsena li thusa ho buisana lipakeng tsa lisele tsa boko, ho tšehetsa sebopeho sa mohopolo le ho hopola. Maemo a lekaneng a serotonin a amahanngoa le ho tsepamisa maikutlo ho matlafalitsoeng, tlhokomelo, le bokhoni ba kelello. Ho netefatsa phepelo e phetseng hantle ea serotonin ho ka thusa ho ntlafatsa kelello, ho ntlafatsa ho ithuta, le ho fokotsa ho fokotseha ha kelello ho amanang le botsofali.
3. Taolo ea takatso ea lijo le boima ba 'mele
Serotonin e ama haholo ebile e thusa ho laola takatso ea rona ea lijo le boitšoaro ba rona ba ho ja. Maemo a serotonin bokong a susumetsa maikutlo a rona a tlala le tlala, a ama khetho ea rona ea lijo le taolo ea likarolo. Ho phaella moo, serotonin e boetse e hlahisoa ka maleng, 'me khaello ea serotonin e ka lebisa ho ja ho tlōla, takatso ea lijo tse nang le lik'habohaedreite tse ngata, le kotsi e eketsehileng ea botenya. Ka ho boloka maemo a nepahetseng a serotonin, re ka laola takatso ea rona ea lijo hamolemo, ra etsa khetho e nepahetseng ea lijo, ra fokotsa litakatso le ho boloka boima ba 'mele bo botle.
4. Khothalletsa ho robala ka boiketlo
Boroko bo botle ke ba bohlokoa bakeng sa bophelo bo botle ba 'mele le ba kelello. Serotonin e bapala karolo ea bohlokoa ho khothaletseng mekhoa ea ho robala e phetseng hantle. E thusa ho laola nako ea ho robala le ho tsoha, ho re lumella ho robala ka potlako, ho robala nako e telele, le ho fumana boroko bo eketsehileng. Maemo a serotonin a sa lekaneng a ka etsa hore motho a hlobaele, a sitisoe ke ho robala le ho robala motšehare. Ka ho etsa bonnete ba hore serotonin e lekaneng e hlahisoa, re ka ntlafatsa boleng ba boroko ba rona mme ra tsoha re ikutloa re khatholohile ebile re le matla.
5. Tšehetsa bophelo bo botle ba tšilo ea lijo
Ntle le liphello tsa eona bokong, serotonin e boetse e ama tsamaiso ea tšilo ea lijo. Hoo e ka bang 90% ea serotonin e fumanoa ka maleng 'me e na le boikarabelo ba ho laola tšebetso ea mala. E thusa ho laola ho sisinyeha ha mala, ho khothaletsa tšilo ea lijo hantle, 'me e kenya letsoho bophelong bo botle ba mala. Ho se leka-lekane ha serotonin ho 'nile ha amahanngoa le mathata a tšilo ea lijo a kang irritable bowel syndrome (IBS) le lefu la ho ruruha ha mala (IBD). Ka ho boloka maemo a serotonin a nepahetseng, re ka khothaletsa bophelo bo botle ba mala le ho fokotsa kotsi ea mathata a tšilo ea lijo.
Ithute ka matšoao a khaello:
●Ho tepella maikutlo, ho tepella maikutlo
● Bothata ba ho robala
● Ho fola ha maqeba hampe
● mohopolo o fosahetseng
●Mathata a ho sila lijo
● Litšitiso tsa setifikeiti
●Ho hloka takatso ea lijo
Fumana lebaka:
● Ho se je hantle: haholo-holo ho akarelletsa ho ja hanngoe feela, lijo tse haelloang ke limatlafatsi le bulimia.
● Malabsorption: Maemo a mang, a kang lefu la celiac le lefu la ho ruruha ha mala, a ka ’na a sitisa ’mele ho monya limatlafatsi.
● Lithethefatsi: Lithethefatsi tse ling li ka ’na tsa sitisa ho monya kapa ho sebelisoa ha limatlafatsi tse itseng.
● Ho se tsitse ha maikutlo: ho tepella maikutlo, ho tšoenyeha.
Li-SSRI li sebetsa ka ho eketsa maemo a serotonin bokong. Serotonin ke neurotransmitter e bapalang karolo ea bohlokoa ho laola maikutlo, maikutlo le bophelo bo botle ka kakaretso. Ka ho thibela ho tsosolosoa ha serotonin, SSRIs e netefatsa hore e lula e le li-synapse nako e telele, kahoo e ntlafatsa liphello tsa eona ho laola maikutlo.
Kamoo SSRIs e sebetsang kateng
Li-SSRI li sebetsa ka ho thibela ho tsosolosoa ha serotonin bokong. Mochine ona o kenyelletsa li-SSRI tse tlamang sepalangoang sa serotonin, ho se thibela ho monya serotonin ho khutlela liseleng tsa methapo. Ka lebaka leo, serotonin e sala e le lekhalo la synaptic pakeng tsa lisele tsa methapo, e ntlafatsa phetiso ea eona le ho matlafatsa liphello tsa eona tsa ho fetola maikutlo.
Ke habohlokoa ho hlokomela hore li-SSRI ha li eketse tlhahiso ea serotonin; ho e-na le hoo ba fetola ho fumaneha le katleho ea serotonin e teng. Ka ho lumella serotonin ho lula nako e telele ka har'a synaptic cleft, SSRIs e thusa ho lefella maemo a tlaase a serotonin le ho tsosolosa botsitso bokong.
Ke habohlokoa ho bolela hore tianeptine hemisulfate monohydrate ke serotonin reuptake enhancer (SSRE) e khethiloeng, e bolelang hore e ntlafatsa ho tsosolosoa ha serotonin bokong, kahoo e matlafatsa hippocampal neurons Synaptic plasticity ho ntlafatsa maikutlo le maemo a maikutlo.
SSRIs le litla-morao
Le hoja ka kakaretso li-SSRI li nkoa li sireletsehile ebile li mamelloa hantle, li ka 'na tsa tla le litla-morao tse ling. Litla-morao tse tloaelehileng li ka kenyelletsa ho nyekeloa ke pelo, ho tsekela, hlooho, le hoja liphello tsena li ka fapana ho ea ka motho. Ke habohlokoa hore bakuli ba buisane le litsebi tsa bona tsa bongaka ka matšoenyeho leha e le afe kapa litla-morao e le hore ho ka etsoa tlhahlobo e haufi-ufi le liphetoho tse nepahetseng, haeba ho hlokahala.
P: Na ho na le mekhoa ea bophelo e ka fokotsang maemo a serotonin?
K: E, ho noa joala ho feta tekano, lijo tse sa jeng hantle, ho se ikoetlise, ho imeloa kelellong nako e telele le meriana e itseng e kang e thibelang ho tepella maikutlo ho ka ’na ha fokotsa tekanyo ea serotonin.
P: Ke mokhoa ofe oa ho eketsa maemo a serotonin ka tlhaho?
A: Mokhoa o akaretsang o lokela ho amoheloa ho matlafatsa maemo a serotonin ka tlhaho. Sena se akarelletsa ho ja lijo tse leka-lekaneng, ho ikoetlisa kamehla, ho fumana letsatsi le lekaneng, ho laola khatello ea kelello ka katleho, le ho nahana ka tlatsetso tlas’a tataiso ea litsebi haeba ho hlokahala.
Boitlhotlhollo: Sengoloa sena ke sa tlhaiso-leseling e akaretsang feela 'me ha ea lokela ho nkuoa e le keletso efe kapa efe ea bongaka. Tse ling tsa litaba tsa poso ea blog li tsoa Marang-rang mme ha se setsebi. Sebaka sena sa marang-rang se na le boikarabello ba ho hlophisa, ho hlophisa le ho hlophisa lingoliloeng. Sepheo sa ho fetisa boitsebiso bo bongata ha se bolele hore u lumellana le maikutlo a eona kapa u tiisa bonnete ba litaba tsa eona. Kamehla buisana le setsebi sa tlhokomelo ea bophelo pele u sebelisa li-supplement leha e le life kapa u etsa liphetoho tsamaisong ea tlhokomelo ea bophelo.
Nako ea poso: Oct-07-2023