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Ho Reka Oleoylethanolamide Powder: Ho Fumana Lihlahisoa tsa Boleng Hokae?

Lefatšeng le ntseng le hola la bophelo bo botle le bophelo bo botle, oleoylethanolamide (OEA) e se e le tlatsetso e tsebahalang e tsebahalang ka melemo e ka bang teng taolong ea boima ba 'mele, taolo ea takatso ea lijo le bophelo bo botle ba metabolic. Tlhokahalo ea lihlahisoa tsa phofo ea premium oleoylethanolamide e eketsehile ha batho ba bangata ba ntse ba tseba melemo ea eona. Leha ho le joalo, ho fumana OEA ea boleng bo holimo e ka ba mosebetsi o boima ka lebaka la likhetho tse ngata tse teng.

Ka ho tseba hore na u batla eng le hore na u ka reka hokae, u ka etsa liqeto tse nang le tsebo tse lumellanang le lipakane tsa bophelo ba hau. Ha u khetha oleoylethanolamide, kamehla u etelletse pele bohloeki, boleng le ho hlaka. Ke ka tsela ena feela u ka khethang sehlahisoa sa phofo sa oleoylethanolamide se finyellang litlhoko tsa hau.

Mehloli ea oleoylethanolamide ke efe?

Oleoylethanolamide (OEA),kapa oleoylethanolamide, ke lipid e hlahang ka tlhaho e entsoeng 'meleng, haholo-holo ka maleng a manyenyane. E tsoa ho karabelo ea enzymatic ea oleic acid (e leng monounsaturated fatty acid e fumanoang mafura a fapa-fapaneng a lijo) le ethanolamine, e leng motsoako oa bobeli oa amide o entsoeng ka lipophilic oleic acid le hydrophilic ethanolamine.

OEA hape ke molek'hule ea lipid e etsahalang ka tlhaho liphatseng tse ling tsa liphoofolo le limela. E fumaneha haholo liphatseng tsa liphoofolo le tsa limela joalo ka phofo ea cocoa, soya le linate, empa litaba tsa eona li tlase haholo. Ke feela ha tikoloho ea kantle e fetoha kapa lijo li hlohlelletsoa, ​​lisele tsa lisele tsa 'mele Ntho ena e tla hlahisoa ka bongata, kahoo OEA e ka boela ea sebelisoa e le tlatsetso ea lijo.

OEA ke molek'hule ea amphiphilic eo ka tloaelo e sebelisoang e le setlolo le se hloekisang indastering ea lik'hemik'hale. Leha ho le joalo, lipatlisiso tse ling li fumane hore OEA e ka sebetsa e le molek'hule e bonts'ang lipid ka har'a axis ea boko le ho bonts'a letoto la mesebetsi ea tlhaho 'meleng, ho kenyelletsa: ho laola takatso ea lijo, ho ntlafatsa metabolism ea lipid, ho matlafatsa mohopolo le temoho le mesebetsi e meng. Har'a tsona, mesebetsi ea OEA ea ho laola takatso ea lijo le ho ntlafatsa metabolism ea lipid e fumane tlhokomelo e kholo.

OEA e sebetsa joang?

Oleoylethanolamide (OEA) ke molek'hule ea endogenous lipid e tšoaeang 'me ke ea sehlopha sa metsoako ea ethanolamine. Haholo-holo e bapala karolo ea 'mele ka ho laola mekhoa e kang takatso ea lijo, metabolism ea matla le mafura a acid oxidation. OEA e entsoe haholo ka maleng a manyane mme e ama tsamaiso ea methapo le lits'ebetso tsa metabolism ka ho tlama li-receptor tse itseng.

Oleylethanolamide e sebetsa ka mekhoa e mengata:

● PPAR-α activation: OEA e tlama le ho kenya tšebetsong PPAR-α, e leng receptor ea nyutlelie e amehang ho metabolism ea lipid, e thusang ho fokotsa ho ja lijo le ho eketsa tšebeliso ea matla.

● E susumetsa lipid oxidation: Ka ho kenya PPAR-α, OEA e ka ntlafatsa ho bola ha mafura a acid sebeteng le ho khothalletsa tšebeliso ea matla.

● Taolo ea axis ea mala le boko: OEA e susumetsa matšoao a ho khora ka ho ama mothapo oa vagus, o tsamaisang melaetsa pakeng tsa mala le boko.

ECS (Endocannabinoid System) ke mokhoa o rarahaneng oa pontšo ea lisele tse kenyelletsang li-endocannabinoids (tse kang cannabinoids), li-receptor tsa tsona (CB1 le CB2), le li-enzyme tse amanang le synthesis le degradation. ECS e phetha karolo ea bohlokoa ho laola mekhoa e sa tšoaneng ea 'mele, ho akarelletsa le takatso ea lijo, maikutlo a bohloko, maikutlo, mohopolo, le likarabo tsa' mele oa ho itšireletsa mafung.

Mokhoa oo ECS o amang mesebetsi ea 'mele ka ona ke o latelang:

Ho laola tsoelo-pele ea methapo ea kutlo le polasetiki ea synaptic: ECS e phetha karolo ea bohlokoa khōlong le nts'etsopele ea lisele tsa methapo, ho kenyelletsa le mekhoa e kang neurogenesis, glia formation, neuronal migration, synaptogenesis, le synaptic pruning. CB1R le AEA li phetha karolo ea bohlokoa nakong ea tsoelo-pele ea motho 'me li amahanngoa le phapang ea lisele le ho lelefatsa ha axonal tsamaisong ea methapo e bohareng.

E fokotsa bohloko le moputso: Li-cannabinoids li fokotsa bohloko ka ho sebetsana le lipheo tse ngata 'me li bontšitsoe ho imolla mefuta e fapaneng ea bohloko. ECS e boetse e bohlokoa ho litlamorao tse khotsofatsang tsa lintho tse lemalloang, tse susumetsang khetho le boitšoaro bo bocha bakeng sa lintho tse fapaneng tse lemalloang.

E laola ts'ebetso ea maikutlo le mohopolo: ECS e ameha ho laola ho tšoenyeha 'me e ama mekhoa ea ho ithuta, ho boloka, ho hopola le ho lemoha mefuta e sa tšoaneng ea mohopolo. CB1R e bapala karolo mosebetsing oa libaka tse ngata tsa boko 'me e na le liphello tse ka bang teng tsa taolo maikutlong le mohopolong.

E laola tsamaiso ea 'mele ea ho itšireletsa mafung le mesebetsi e meng: ECS e fumanoa liseleng tsa' mele oa ho itšireletsa mafung 'me e ka susumetsa mosebetsi oa tsona. AEA e ka thibela ho lokolloa ha li-cytokine tsa pro-inflammatory le ho laola ts'ebetso ea 'mele ea ho itšireletsa mafung. Ho phaella moo, ECS e boetse e ameha ho laola takatso ea lijo, boitšoaro ba ho ja, le mesebetsi ea 'mele ea mekhoa e mengata ea litho.

Kamano pakeng tsa oleoylethanolamine le ECS e bonahala haholo-holo likarolong tse latelang:

Litšebelisano: OEA e ka ama takatso ea lijo le tekanyo ea matla ka ho sebelisana le li-receptors ho ECS. Ho nahanoa hore OEA e hatella takatso ea lijo le ho khothaletsa oxidation ea mafura acid.

Mokhoa oa ho laola: OEA e ka ama mosebetsi oa ECS ka ho laola ho qaptjoa le ho senyeha ha li-endocannabinoids, ka hona ho bapala karolo ea matla a metabolism le taolo ea takatso ea lijo.

Karolo e ka bang teng: Ka lebaka la karolo ea bona ea ho laola metabolism le takatso ea lijo, bafuputsi ba ntse ba lekola karolo eo ba ka e bapalang ho botenya, lefu la metabolism le mafu a mang a amanang le ona.

Ka kakaretso, tšebelisano pakeng tsa oleoylethanolamine le tsamaiso ea endocannabinoid ke sebaka se sebetsang sa lipatlisiso 'me se ka fana ka lintlha tse ncha tsa kutloisiso le ho phekola mafu a amanang le metabolism.

Oleoylethanolamide Powder

OEA e molemo bakeng sa eng?

 

1. Laola takatso ea lijo le ho theola boima ba 'mele

OEA ke inhibitor ea bohlokoa ea ho ja lijo, 'me mosebetsi oa eona o ka sehloohong ke ho thusa ho fokotsa botenya. Ente ea Intraperitoneal ea OEA e ka fokotsa ho ja lijo le boima ba 'mele ho likhoto. Tsamaiso ea molomo ea OEA le eona e ka ba le litlamorao tse ts'oanang, empa ente ea intracerebroventricular ea OEA ha e joalo. Ha e ame ho jeoa ha likhoto. Phello e kholo ea ho theola boima ba 'mele ea OEA ke hore e ka baka maikutlo a ho khora, ka hona ho laola ho ja lijo tse ngata. Ho eketsa motsoako o itseng oa OEA phepelong ea litoeba tse tloaelehileng kapa tse nonneng ho ka fokotsa takatso ea lijo le boima ba litoeba.

OEA ha e thibele feela ho monya mafura ka mpeng, empa hape e potlakisa beta oxidation ea mafura acid ka ho khothaletsa hydrolysis ea triglycerides ka har'a lithane tsa peripheral (sebete le mafura), qetellong e fokotsa ho bokellana ha mafura le ho fihlela taolo ea boima ba 'mele.

2. Fokotsa lipids ea mali le ho hanyetsa atherosclerosis

Peroxisome proliferator-activated receptor-α (PPAR-α) ke mofuta oa receptor o amanang haufi-ufi le mesebetsi ea metabolism 'meleng. PPAR-α e nka karolo ho metabolism ea lipid ka ho tlama karolo ea karabo ea peroxisome proliferator. Lipalangoang tsa metabolism, taolo ea 'mele ea ho itšireletsa mafung, anti-inflammation, anti-proliferation le mekhoa e meng e amanang le eona e tsoela pele ho phetha karolo ea ho laola lipids tsa mali le anti-atherosclerosis.

OEA ke analog ea endocannabinoid e hlahisoang ha lisele tsa 'mele li tsosoa. Liphuputso li bontšitse hore OEA e etsa hore PPAR-M e sebetse, e fokotsa ho lokolloa ha endothelin-1, e thibela vasoconstriction le ho ata ha lisele tsa mesifa e boreleli, e khothalletsa vasodilation, 'me ka nako e ts'oanang e eketsa motsoako oa endothelial nitric oxide synthase le ho etsa hore ho be le nitric oxide e eketsehileng. synthase. naetrojene, ka hona e fokotsa tlhahiso ea limolek'hule tsa vascular cell adhesion, ho fihlela litlamorao tse khahlanong le ho ruruha, le ho fana ka litlamorao tsa ho theola lipids tsa mali le anti-atherosclerosis.

3. Laola bulimia

Bothata ba ho ja ho tlōla tekano (BED) ke bothata bo atileng ka ho fetisisa ba ho ja, bo khetholloang ke ho ja ho sa laoleheng, ho qobelloang, ho tsamaeang le maikutlo a matla a ho lahleheloa ke taolo, lihlong, ho ikutloa molato, ho nyonya le ho tšoenyeha.

Le hoja lintho tse bakang ho itlopa lijo li e-s'o fihlele qeto, ho na le bopaki ba hore ho ja lijo le khatello ea bophelo ke lintho tse tloaelehileng tse bakang ho itlopa lijo. Liphuputso tse ling li bontšitse hore mekhoa ea neurobiological ea ho ja ho tlōla e lebisa tlhokomelo ho ts'ebetsong ha tsamaiso ea mesocortical limbic dopamine (DA) le boko ba serotonin (5-HT) le pontšo ea norepinephrine (NA).

Oleylethanolamide (OEA) ke lipid metabolite ea tlhaho e nang le karolo ea bohlokoa taolong ea takatso ea lijo, taolo ea matla le taolo ea boima ba 'mele. Joaloka molaoli oa bohlokoa oa 'mele, OEA e sebelisana le peroxisome proliferator-activated receptor α (PPAR-α) ho khothalletsa ho khora le ho susumetsa mafura a oxidation. Bafuputsi ba 'nile ba hlahloba bokhoni ba phekolo ea OEA, e leng se lebisang ho nts'etsopele ea lisebelisoa tsa oleoylethanolamide tse etselitsoeng ho tšehetsa mesebetsi ena.

Oleoylethanolamide Powder1

Seo U Lokelang ho se Tseba Pele U Reka Oleoylethanolamide Powder

Pele o rekaOleylethanolamide (OEA) phofo, nahana ka lintlha tse latelang:

1. Utloisisa OEA

Seo e leng sona: OEA ke ethanolamide e mafura e nang le mafura e bapalang karolo ho laola takatso ea lijo, metabolism, le homeostasis ea matla. E ka thusa ho laola boima ba 'mele, ho ntlafatsa lipid metabolism, le ho eketsa tšebeliso ea matla.

2. Boleng le Bohloeki

Mohloli: Reka ho tsoa ho barekisi ba tšepahalang ba fanang ka tlhahlobo ea mokha oa boraro bakeng sa bohloeki le boleng.

Setifikeiti sa Tlhahlobo (CoA): E netefatsa hore sehlahisoa se na le CoA e netefatsang sebopeho sa sona le ho se be teng ha litšila.

3. Tekanyo le tšebeliso

Tekanyetso e khothalelitsoeng: Patlisiso e khothalelitse litekanyetso le ho buisana le setsebi sa tlhokomelo ea bophelo bakeng sa likhothaletso tse ikhethileng.

Mefuta e jeoang: OEA e tla ka mefuta e mengata (phofo, capsule). Khetha sehlahisoa se lumellanang le mokhoa oa hau oa bophelo.

4. Litla-morao tse ka bang teng

Litla-morao tse Tloaelehileng: Le hoja ka kakaretso e nkoa e sireletsehile, basebelisi ba bang ba ka 'na ba e-ba le bothata ba ka mpeng kapa litla-morao tse ling tse nyenyane.

Buisana le ngaka ea hau: Haeba u na le bothata ba bongaka bo neng bo le teng pele kapa u noa meriana, buisana le mofani oa tlhokomelo ea bophelo pele u e sebelisa.

5. Boemo ba molao

Melawana: Lekola maemo a molao a OEA naheng ya heno kaha melawana e ka fapana.

6. Polokelo le shelf bophelo

Maemo a polokelo: Etsa bonnete ba hore u utloisisa mokhoa oa ho boloka phofo hantle ho boloka katleho ea eona.

Letsatsi la ho felloa ke nako: Sheba letsatsi la ho felloa ke nako ho netefatsa hore u reka sehlahisoa se secha.

7. Litšenyehelo le boleng

Papiso ea Theko: Bapisa litheko ho tsoa ho barekisi ba fapaneng, empa ela hloko litheko tse tlase haholo tse ka bonts'ang boleng bo tlase.

Reka ka bongata: Haeba u rera ho e sebelisa nako e telele, nahana ka ho reka ka bongata kaha ho ka boloka litšenyehelo.

8. Kopanya le lisebelisoa tse ling

Liphello tsa Synergistic: Batlisisa hore na OEA e sebelisana joang le li-supplement tse ling kapa liphetoho tsa lijo tseo u ka li nahanang.

Ka ho nahana ka lintlha tsena, u ka etsa qeto e nepahetseng haholoanyane ha u reka phofo ea oleoylethanolamide. Kamehla beha pele polokeho le boleng ha u khetha tlatsetso.

Oleoylethanolamide Powder2

U ka Fumana Lihlahisoa tsa Powder tsa boleng ba Oleoylethanolamide hokae?

 

Matsatsi a ile a feta ha u sa tsebe hore na u ka reka phofo ea oleylethanolamine hokae. Kajeno, ho na le libaka tse ngata moo u ka rekang phofo ea magnesium acetyl taurate. Ka lebaka la Marang-rang, u ka reka ntho leha e le efe ntle le ho tloha lapeng. Ho ba inthaneteng ha ho nolofatse mosebetsi oa hau feela, ho boetse ho etsa hore boiphihlelo ba hau ba ho reka bo be bonolo haholoanyane. U boetse u na le monyetla oa ho bala ho eketsehileng ka oleoylethanolamine ena e hlollang pele u etsa qeto ea ho reka.

Suzhou Myland Pharm & Nutrition Inc. ke moetsi ea ngolisitsoeng ke FDA ea fanang ka phofo ea Oleoylethanolamide (OEA) ea boleng bo phahameng le bo hloekileng.

Ho Suzhou Myland Pharm re ikemiselitse ho fana ka lihlahisoa tsa boleng bo holimo ka litheko tse ntle. Phofo ea rona ea Oleoylethanolamide (OEA) e lekoa ka matla bakeng sa bohloeki le potency, ho netefatsa hore o fumana tlatsetso ea boleng bo holimo eo u ka e tšepang. Hore na o batla ho ts'ehetsa bophelo bo botle ba cellular, ho matlafatsa sesole sa hau sa 'mele kapa ho ntlafatsa bophelo bo botle ka kakaretso, phofo ea rona ea Oleoylethanolamide (OEA) ke khetho e phethahetseng.

Ka boiphihlelo ba lilemo tse 30 'me e susumetsoa ke thekenoloji e phahameng le maano a R&D a ntlafalitsoeng haholo, Suzhou Myland Pharm e hlahisitse lihlahisoa tse ngata tsa tlholisano mme e fetohile tlatsetso e ncha ea mahlale a bophelo, ho kopanya tloaelo le k'hamphani ea lits'ebeletso tsa tlhahiso.

Ntle le moo, Suzhou Myland Pharm le eona ke moetsi ea ngolisitsoeng ke FDA. Lisebelisoa tsa R&D tsa k'hamphani, lisebelisoa tsa tlhahiso, le lisebelisoa tsa tlhahlobo ke tsa sejoale-joale ebile li na le mesebetsi e mengata, 'me li ka hlahisa lik'hemik'hale ho tloha ho limiligrama ho isa ho lithane ka tekanyo,' me li lumellana le litekanyetso tsa ISO 9001 le litlhaloso tsa tlhahiso ea GMP.

P: Oleoylethanolamide (OEA) ke eng mme melemo ea eona ke efe?
A: Oleoylethanolamide (OEA) ke lipid e hlahang ka tlhaho e bapalang karolo ho laola takatso ea lijo, metabolism, le botsitso ba matla. Hangata e sebelisoa e le tlatsetso ea lijo bakeng sa ho laola boima ba 'mele, ho khothalletsa ho khora, le ho matlafatsa metabolism ea mafura.

P: Ke tseba joang boleng ba phofo ea Oleoylethanolamide?
A: Ho fumana boleng ba phofo ea Oleoylethanolamide, batla lihlahisoa tse fanang ka Setifikeiti sa Tlhahlobo (COA) ho tsoa ho laborateng ea boraro. Ho feta moo, sheba litlhahlobo tsa bareki, pepeneneng ea motsoako, le hore na sehlahisoa ha se na litšila le li-filler.

P: Ke lokela ho nahana ka eng ha ke reka phofo ea Oleoylethanolamide?
A: Ha u reka phofo ea Oleoylethanolamide, nahana ka lintlha tse kang mohloli oa sehlahisoa, khatello ea OEA, boteng ba li-additives leha e le life, botumo ba moetsi le maikutlo a bareki. Hape ke habohlokoa ho hlahloba litaelo tse nepahetseng tsa ho boloka le ho tšoara.

Boitlhotlhollo: Sengoloa sena ke sa tlhaiso-leseling e akaretsang feela 'me ha ea lokela ho nkuoa e le keletso efe kapa efe ea bongaka. Tse ling tsa litaba tsa poso ea blog li tsoa Marang-rang mme ha se setsebi. Sebaka sena sa marang-rang se na le boikarabello ba ho hlophisa, ho hlophisa le ho hlophisa lingoliloeng. Sepheo sa ho fetisa boitsebiso bo bongata ha se bolele hore u lumellana le maikutlo a eona kapa u tiisa bonnete ba litaba tsa eona. Kamehla buisana le setsebi sa tlhokomelo ea bophelo pele u sebelisa li-supplement leha e le life kapa u etsa liphetoho tsamaisong ea tlhokomelo ea bophelo.


Nako ea poso: Sep-27-2024