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Mokhoa oa ho Khetha Phofo e Molemohali ea NAD+: Tataiso ea Moreki

NAD+ (Beta-Nicotinamide Adenine Dinucleotide) ke coenzyme e fumanoang liseleng tsohle tse phelang 'me e bohlokoa bakeng sa mekhoa e sa tšoaneng ea likokoana-hloko, ho kenyeletsa tlhahiso ea matla le tokiso ea DNA. Ha re ntse re tsofala, maemo a rona a NAD+ a fokotseha, a lebisang mathateng a mangata a bophelo bo botle. Ho loantša bothata bona, batho ba bangata ba retelehela ho li-supplement tsa NAD + ka mokhoa oa phofo. Leha ho le joalo, ka likhetho tse ngata haholo moo, ho fumana hore na ke phofo efe ea NAD + e u loketseng ho ka ba thata. Ho khetha phofo e ntle ka ho fetisisa ea NAD+ ho hloka ho nahanoa ka hloko ka bohloeki, bioavailability, litekanyetso, ho hlaka, le maikutlo a bareki. Ka ho beha lintlha tsena pele, u ka etsa qeto e nang le tsebo 'me ua khetha phofo ea NAD + ea boleng bo holimo e tšehetsang bophelo bo botle le boiketlo ba hau.

Na NAD+ e hlile ea sebetsa?

NAD e hlaha ka tlhaho liseleng tsa rona,haholo-holo ka cytoplasm le mitochondria ea bona, leha ho le joalo, maemo a tlhaho a NAD a fokotseha ha re ntse re hōla (lilemo tse ling le tse ling tsa 20, ha e le hantle), ho baka liphello tse tloaelehileng tsa botsofali, Tse kang ho fokotseha ha matla le ho eketseha ha bohloko le bohloko. Ho feta moo, ho fokotseha ho amanang le botsofali ho NAD ho amahanngoa le mafu a mang a amanang le lilemo, joalo ka mofetše, ho fokotseha ha kelello le bofokoli.

NAD+ ha se hormone, ke coenzyme. NAD+ e ka ntlafatsa bokhoni ba DNA ea ho itokisa, ea lelefatsa nako ea bophelo ka ho khutlisa ho fokotseha ha mitochondria, le ho sireletsa DNA le tšenyo ea mitochondrial. 'Me e ka ntlafatsa botsitso ba chromosome. NAD+ e boetse e tsejoa e le "molek'hule ea mohlolo" e khutlisetsang le ho boloka bophelo bo botle ba lisele. Lithutong tsa liphoofolo, ho netefalitsoe hore e na le matla a matla a ho phekola mafu a fapaneng a kang lefu la pelo, lefu la tsoekere, lefu la Alzheimer le botenya.

NAD + e kenya letsoho liketsong tse fapa-fapaneng tsa lik'hemik'hale tsa lik'hemik'hale ka har'a lisele, tse kang glycolysis, fatty acid oxidation, tricarboxylic acid cycle, breathing chain, joalo-joalo Ka mekhoa ena, NAD + e sebetsa e le transmitter ea hydrogen, e amohelang li-electrone le hydrogen ho tloha substrates ebe e li fetisetsa ho. Limolek'hule tse ling, joalo ka NADH le FAD, ho boloka tekano ea intracellular redox. NAD+ e bapala karolo ea bohlokoa tlhahisong ea matla a cellular, tšireletso ea radical mahala, tokiso ea DNA, le lipontšo.

Ntle le moo, NAD+ e boetse e amana haufi-ufi le botsofali, 'me maemo a eona a fokotseha ka lilemo. Ka hona, ho boloka maemo a NAD+ ho bapala karolo ea bohlokoa ho liehisa botsofali, ho matlafatsa matla, ho khothaletsa tokiso ea lisele, ho ntlafatsa ts'ebetso ea kelello, le ho laola metabolism.

Haholo-holo, botsofali bo tsamaisana le ho fokotseha ho tsoelang pele ha lisele le lisele tsa NAD+ ka har'a mefuta e fapaneng ea lintho tse phelang, ho kenyeletsoa litoeba le batho.

Ka hona, ho tlatsa litaba tsa NAD + ka nako 'meleng ho ka liehisa botsofali le ho netefatsa bophelo bo botle. Haeba u batla hore lilemo e be palo feela, tlatselletsa NAD + kapele kamoo ho ka khonehang ho etsa hore o shebahale o le monyane ho tloha kahare ho ea kantle.

Maemo a NAD + a theoha ka lilemo, haholo hobane sekhahla sa tlhahiso ea eona ha se khone ho tsamaisana le sekhahla sa tšebeliso.

Palo e kholo ea lithuto li bonts'itse hore ho fokotseha ha maemo a NAD + ho amana le mafu a mangata a amanang le botsofali, ho kenyelletsa le ho fokotseha ha kelello, ho ruruha, mofetše, mafu a metabolic, sarcopenia, mafu a neurodegenerative, jj.

Ke ka lebaka lena re hlokang li-supplement tsa NAD +. Joalo ka mofuta oa rona oa 3 collagen, e lula e lahleha.

NAD + e ka hanela botsofali. Molao-motheo oa eona ke ofe?

nad+ e kenya tšebetsong enzyme ea tokiso ea liphatsa tsa lefutso ea parp1

E thusa ho lokisa DNA E 'ngoe ea lisosa tsa botsofali ke tšenyo ea DNA. Moriri oa hau o mosoeu, mahe a bomme le litho tse ling tse fokotsehang, kaofela li amana le tšenyo ea DNA. Ho robala bosiu haholo le ho imeloa kelellong ho tla mpefatsa tšenyo ea DNA.

Liphuputso li fumane hore NAD+ e thusa ho kenya tšebetsong mofuta oa PARP1 (o sebetsang e le mohanyetsi oa pele oa ho lemoha tšenyo ea DNA, ebe o khothalletsa khetho ea litsela tsa ho lokisa. lokisa Lintlha li sebelisana le ho li fetola, ka tsela eo li ntlafatsa ts'ebetso ea ho lokisa), ka tsela eo ho lokisa tšenyo ea DNA le ho khothalletsa ho tsosoa ha liphetoho tsa metabolism.

Ka kakaretso, NAD + e ka ama ka kotloloho le ka tsela e sa tobang mesebetsi e mengata ea bohlokoa ea lisele, ho kenyelletsa le litsela tsa metabolic, tokiso ea DNA, nchafatso ea chromatin, senescence ea lisele, ts'ebetso ea lisele tsa 'mele, joalo-joalo, ka hona, e liehisa ts'ebetso ea botsofali ba motho.

NAD+ phofo5

NAD supplement e sebelisetsoa eng?

NAD+ ke khutsufatso ea Senyesemane ea Nicotinamide adenine dinucleotide. Lebitso la eona le felletseng ka Sechaena ke nicotinamide adenine dinucleotide, kapa Coenzyme I ka bokhutšoanyane. Joaloka coenzyme e fetisang li-ion tsa hydrogen, NAD + e bapala karolo likarolong tse ngata tsa metabolism ea motho, ho akarelletsa le glycolysis, Gluconeogenesis, tricarboxylic acid cycle, joalo-joalo Liphuputso tse ling li bontšitse hore ho fokotseha ha NAD + ho amana le lilemo, 'me mekhoa ea physiological e buisana. ka NAD + li amana le botsofali, mafu a metabolic, methapo ea kutlo le mofets'e, ho kenyelletsa le ho laola cell homeostasis, li-sirtuin tse tsejoang e le "liphatsa tsa lefutso tsa nako e telele", ho lokisa DNA, PARPs liprotheine tsa lelapa tse amanang le necroptosis le CD38 tse thusang ho bontša khalsiamo.

Khahlanong le Botsofali

Botsofali bo bolela mokhoa oo lisele li khaotsang ho arohana ka mokhoa o ke keng oa khutlisoa. Tšenyo e sa lokisoang ea DNA kapa khatello ea cellular e ka baka senescence. Botsofali ka kakaretso bo hlalosoa e le mokhoa oa ho senyeha butle-butle ha mesebetsi ea fisioloji ka lilemo; lipontšo tsa ka ntle ke liphetoho tsa 'mele tse bakoang ke tahlehelo ea mesifa le masapo,' me lipontšo tsa ka hare li fokotsehile metabolism ea motheo le ts'ebetso ea 'mele ea ho itšireletsa mafung.

Bo-rasaense ba ithutile batho ba phetseng nako e telele, 'me liphello tsa lipatlisiso li bontša hore ho na le liphatsa tsa lefutso tse amanang le nako e telele ho batho ba phelang nako e telele - "Sirtuins gene". Mofuta ona oa lefutso o tla kenya letsoho ts'ebetsong ea tokiso ea phepelo ea matla a 'mele le ho ikatisa ha DNA ho boloka botšepehi le botsitso ba lefutso, ho tlosa lisele tse tsofetseng, ho ntlafatsa sesole sa' mele ka litlamorao tse khahlanong le ho ruruha le antioxidant, le ho liehisa botsofali ba lisele tse tloaelehileng.

Ts'ebetso e le 'ngoe feela e lebisitsoeng ea liphatsa tsa bophelo bo bolelele "Sirtuins" -NAD+

NAD+ e bohlokoa ho boloka bophelo bo botle ba 'mele le botsitso. Metabolism, redox, tlhokomelo le tokiso ea DNA, botsitso ba liphatsa tsa lefutso, taolo ea epigenetic, joalo-joalo kaofela li hloka ho kenya letsoho ha NAD +.

NAD+ e boloka puisano ea lik'hemik'hale pakeng tsa nucleus le mitochondria, 'me puisano e fokolang ke sesosa sa bohlokoa sa botsofali ba lisele.

NAD+ e ka tlosa palo e ntseng e eketseha ea likhoutu tse fosahetseng tsa DNA nakong ea metabolism ea lisele, ea boloka polelo e tloaelehileng ea liphatsa tsa lefutso, ea boloka ts'ebetso e tloaelehileng ea lisele, le ho fokotsa botsofali ba lisele tsa motho.

Lokisa tšenyo ea DNA

NAD+ ke karolo ea bohlokoa bakeng sa enzyme ea tokiso ea DNA PARP, e nang le tšusumetso e kholo ho lokisoeng ha DNA, polelo ea liphatsa tsa lefutso, nts'etsopele ea lisele, ho phela ha lisele, kaho ea chromosome, le botsitso ba liphatsa tsa lefutso.

Kenya protheine ea bophelo bo bolelele

Li-Sirtuin hangata li bitsoa lelapa la protheine ea nako e telele 'me li bapala karolo ea bohlokoa ea taolo mesebetsing ea lisele, joalo ka ho ruruha, kholo ea lisele, morethetho oa circadian, metabolism ea matla, tšebetso ea neuronal, le ho hanyetsa khatello ea maikutlo, mme NAD + ke enzyme ea bohlokoa bakeng sa ho qaptjoa ha liprotheine tsa nako e telele. . E kenya tšebetsong liprotheine tsohle tse 7 tsa bophelo bo bolelele 'meleng oa motho, e bapala karolo ea bohlokoa ho hanyetsa khatello ea kelello ea cellular, metabolism ea matla, ho thibela phetoho ea lisele, apoptosis le botsofali.

NAD+ phofo4

Fana ka matla

E etsa hore ho be le tlhahiso ea matla a fetang 95% a hlokahalang bakeng sa mesebetsi ea bophelo. Mitochondria liseleng tsa motho ke limela tsa matla tsa lisele. NAD+ ke coenzyme ea bohlokoa ho mitochondria ho hlahisa molek'hule ea matla ATP, e fetolang limatlafatsi ho ba matla a hlokoang ke 'mele oa motho.

Khothalletsa ho nchafatsoa ha methapo ea mali le ho boloka methapo ea mali e le elasticity

Methapo ea mali ke lisele tse hlokahalang bakeng sa mesebetsi ea bophelo. Ha re ntse re hōla, butle-butle methapo ea mali e lahleheloa ke ho feto-fetoha ha eona 'me e ba thata, e teteaneng le e fokolang, e bakang "arteriosclerosis." NAD + e ka eketsa ts'ebetso ea elastin methapong ea mali, ka hona, ea boloka botsitso ba methapo ea mali le ho boloka bophelo bo botle ba methapo ea mali.

Khothalletsa metabolism

Metabolism ke kakaretso ea liphetoho tse fapaneng tsa lik'hemik'hale 'meleng. 'Mele o tla tsoela pele ho fapanyetsana taba le matla. Ha phapanyetsano ena e emisa, bophelo ba 'mele le bona bo tla fela.

Moprofesa Anthony le sehlopha sa hae sa lipatlisiso Univesithing ea California, USA, ba fumane hore NAD+ e ka ntlafatsa ka katleho ho fokotseha ha metabolism ea lisele ho amanang le botsofali, kahoo ea ntlafatsa bophelo bo botle ba batho le ho lelefatsa bophelo.

Sireletsa bophelo bo botle ba pelo

Pelo ke setho sa bohlokoahali sa batho, 'me boemo ba NAD+' meleng bo bapala karolo ea bohlokoa ho boloka tšebetso e tloaelehileng ea pelo. Phokotso ea NAD + e kanna ea amana le pathogenesis ea mafu a mangata a pelo, mme palo e kholo ea lithuto tsa mantlha le eona e netefalitse phello ea tlatsetso ea NAD + ho mafu a pelo.

Thibela mafu a pelo le cerebrovascular

Liphuputso li bontšitse hore hoo e ka bang li-subtypes tse supileng tsa li-sirtuin (SIRT1-SIRT7) li amana le ketsahalo ea lefu la pelo. Li-Sirtuin li nkoa e le liphofu tsa agonistic bakeng sa phekolo ea mafu a pelo, haholo-holo SIRT1.

NAD+ ke eona feela substrate ea Sirtuins. Tlatsetso e nakong ea NAD + 'meleng oa motho e ka kenya tšebetsong tšebetso ea mofuta o mong le o mong oa Sirtuins, ka hona e sireletsa bophelo bo botle ba pelo le ho thibela mafu a pelo.

Khothalletsa ho hola ha moriri

Sesosa se seholo sa ho lahleheloa ke moriri ke tahlehelo ea matla a sele ea 'm'a moriri, mme tahlehelo ea matla a sele ea moriri ke hobane boemo ba NAD + 'meleng oa motho boa fokotseha. Lisele tsa 'm'a tsa moriri ha li na ATP e lekaneng ho etsa protheine ea moriri, ka hona li lahleheloa ke matla le ho lebisa tahlehelong ea moriri. Ka hona, ho tlatsetsa NAD + ho ka matlafatsa potoloho ea acid le ho hlahisa ATP, e le hore lisele tsa 'mè oa moriri li be le bokhoni bo lekaneng ba ho hlahisa protheine ea moriri, kahoo e ntlafatsa ho lahleheloa ke moriri.

NAD + kalafo ea molek'hule ea lisele

Ha lilemo li ntse li eketseha, boemo ba NAD + (Coenzyme I) 'meleng bo tla theoha lefika, le lebisang ka kotloloho ts'ebetsong ea' mele le botsofali ba lisele! Kamora lilemo tse mahareng, boemo ba NAD + 'meleng oa motho bo fokotseha selemo le selemo. Ha u le lilemo li 50, boemo ba NAD + 'meleng ke halofo feela ea seo ha u le lilemo li 20. Ka lilemo tse 80, maemo a NAD + a ka bang 1% feela ea seo ba neng ba le sona ha ba le lilemo li 20.

NAD + Powder vs. Lisebelisoa tse ling: Seo U Lokelang ho se Tseba

Joale, phofshoana ea NAD+ e fapane joang le li-supplement tse ling 'marakeng? A re hlahlobeng lintlha tse ling tsa bohlokoa tseo re lokelang ho nahana ka tsona:

1. Bioavailability:

Phapang e 'ngoe ea mantlha lipakeng tsa phofo ea NAD+ le li-supplement tse ling ke bioavailability ea eona. NAD+ phofo e monngoa habonolo ke 'mele' me e sebelisa li-coenzymes hantle. Ka lehlakoreng le leng, li-supplement tse ling li kanna tsa ba le bioavailability e tlase, ho bolelang hore 'mele o kanna oa se khone ho monya le ho sebelisa metsoako e sebetsang hantle.

2. Mokhoa oa ts'ebetso:

NAD + phofo e sebetsa ka ho tlatsa maemo a NAD + 'meleng, ka hona e ts'ehetsa mesebetsi e fapaneng ea liselefouno. Li-supplement tse ling li ka ba le mekhoa e fapaneng ea ts'ebetso, e shebileng litsela tse itseng kapa litsamaiso 'meleng. Ho utloisisa mekhoa e ikhethileng ea ts'ebetso ea li-supplement tse fapaneng ho ka u thusa ho tseba hore na ke life tse loketseng litlhoko tsa hau.

3. Lipatlisiso le bopaki:

Ha ho nahanoa ka tlatsetso efe kapa efe, ho bohlokoa ho hlahloba lipatlisiso tse teng le bopaki bo tšehetsang katleho le polokeho ea eona. NAD + phofo e bile taba ea lithuto tse ngata, e totobatsang melemo ea eona bakeng sa bophelo bo botle ba cellular le bophelo bo bolelele. Ka lehlakoreng le leng, litlatsetso tse ling li ka ba le lipatlisiso tse fokolang ho tšehetsa liqoso tsa bona. Ho utloisisa bopaki ba mahlale ba tlatsetso ho ka u thusa ho etsa liqeto tse nang le tsebo mabapi le tšebeliso ea eona.

4. Litlhoko le lipakane tsa botho:

Qetellong, qeto ea ho sebelisa phofo ea NAD + kapa litlatsetso tse ling e lokela ho ipapisa le litlhoko tsa hau le lipheo tsa bophelo bo botle. Nahana ka ho buisana le setsebi sa bophelo bo botle kapa setsebi sa phepo e nepahetseng ho fumana hore na ke li-supplement life tse ka u tsoelang molemo haholo. Lintlha tse kang lilemo, mokhoa oa bophelo, le maemo a teng a bophelo bo botle li ka bapala karolo ea ho khetholla mofuta o nepahetseng oa tlatsetso.

NAD + Nalane ea Lipatlisiso

NAD+, bo-rasaense ba ntse ba e ithuta ka lilemo tse 100. NAD+ ha se tšibollo e ncha, empa ke ntho e ithutoang ka lilemo tse fetang 100.

NAD+ e qalile ho fumanoa ka 1904 ke setsebi sa biochemist sa Borithane Sir Arthur Harden, eo hamorao a ileng a hapa Khau ea Nobel ho Chemistry ka 1929.

Ka 1920, Hans von Euler-Chelpin o ile a arola le ho hloekisa NAD+ ka lekhetlo la pele mme a sibolla sebopeho sa eona sa dinucleotide, mme a hapa Khau ea Nobel ho Chemistry ka 1929.

Ka 1930, Otto Warburg o ile a qala ho sibolla karolo ea bohlokoa ea NAD+ e le coenzyme ho metabolism ea matla le matla, mme hamorao a hapa Khau ea Nobel ea Bongaka ka 1931.

Ka 1980, George Birkmayer, moprofesa Lefapheng la Khemistri ea Bongaka Univesithing ea Graz e Austria, o ile a qala ho sebelisa ho fokotsa NAD + ho phekola mafu.

Ka 2012, sehlopha sa lipatlisiso sa Leonard Guarente, sehlopha sa lipatlisiso sa setsebi sa k'hemistri se tummeng lefatšeng Stephen L. Helfand, le sehlopha sa lipatlisiso sa Haim Y. Cohen ka ho latellana se fumane hore NAD + e ka lelefatsa melamu ea Caenorhabditis elegans. Nako ea bophelo ea li-nematode e batla e le 50%, e ka atolosa bophelo ba lintsintsi tsa litholoana ka hoo e ka bang 10% -20%, 'me e ka atolosa bophelo ba litoeba tse tona ka ho feta 10%.

Liphuputso le liphuputso tsa bo-ramahlale ka bophelo li 'nile tsa ntlafatsoa khafetsa le ho phetoa. Ka December 2013, David Sinclair, moprofesa oa liphatsa tsa lefutso Univesithing ea Harvard, o ile a hatisa "Supplementing NAD with NAD" koranteng e phahameng ea thuto ea lefats'e "Cell". "Ka mor'a beke e le 'ngoe ea ho eketseha ha NAD le moemeli, nako ea bophelo ea litoeba e ile ea eketsoa ka 30%. Liphetho tsa lipatlisiso li senotse lekhetlo la pele hore li-supplement tsa NAD+ li ka khutlisa botsofali haholo le ho lelefatsa nako ea bophelo. Patlisiso ena e ile ea tšosa lefats'e mme ea bula tsela ea botumo bakeng sa li-supplement tsa NAD e le lintho tse thibelang botsofali. .

Ka tšibollo ena e makatsang, NAD+ e thehile khokahano e ke keng ea arohana le anti-botsofali. Lilemong tsa morao tjena, lipatlisiso tse mabapi le NAD+ li se li batla li laola likoranta tse phahameng tsa thuto tsa SCI tse kang Science, Nature, le Cell, 'me e se e le tšibollo e makatsang sechabeng sa bongaka. Ho boleloa hore sena Ke mohato oa histori o nkuoeng ke moloko oa batho leetong la ho loantša botsofali le ho lelefatsa bophelo.

NAD+ phofo2

Ho Khetha Letšoao le nepahetseng la NAD + Powder bakeng sa Boleng le Bohloeki

1. Batlisisa ka setumo le ponaletso ea mofuta ona

Ha u nahana ka mofuta o itseng oa phofo oa NAD+, ho bohlokoa ho etsa lipatlisiso ka botumo ba k'hamphani le pepeneneng. Batla mefuta e etelletsang pele pepeneneng lits'ebetsong tsa bona tsa ho fumana le ho etsa. Lihlahisoa tse tsebahalang li tla fana ka leseli le felletseng mabapi le ho fumana phofo ea NAD+, ho kenyeletsoa boleng ba thepa e tala le litekanyetso tsa tlhahiso tseo ba li khomarelang. Ho feta moo, batla maikutlo a bareki le bopaki ho lekanya khotsofalo le boiphihlelo ba basebelisi ba bang ka lihlahisoa tsa cha.

2. Lekola bohloeki ba NAD + phofo

Bohloeki ke ntlha ea bohlokoa ha u khetha mofuta oa phofo oa NAD +. Phofo ea boleng bo holimo ea NAD+ ha ea lokela ho ba le litšila le li-filler, ho netefatsa hore o fumana sehlahisoa se hloekileng le se sebetsang. Batla lihlahisoa tse etsang liteko tsa motho oa boraro ho netefatsa bohloeki ba phofo ea bona ea NAD+. Teko ea batho ba bang e fana ka tiisetso e eketsehileng ea hore lihlahisoa li finyella litekanyetso tse phahameng ka ho fetisisa tsa bohloeki 'me ha li na lintho tse kotsi.

NAD+ phofo1

3. Nahana ka mekhoa ea tlhahiso le litekanyetso tsa boleng

Ts'ebetso ea tlhahiso e phetha karolo ea bohlokoa ho boleng ba NAD + phofo. Khetha mefuta e latelang mehato e tiileng ea taolo ea boleng 'me u khomarele Mekhoa e Metle ea Tlhahiso (GMP). Setifikeiti sa GMP se netefatsa hore lihlahisoa li hlahisoa sebakeng se hloekileng le se laoloang, ho fokotsa kotsi ea tšoaetso le ho netefatsa boleng bo tsitsitseng. Ho feta moo, botsa ka boitlamo ba khoebo ho ts'ebetsong le mekhoa e metle ea ho fumana chelete, kaha lintlha tsena li ka bonts'a boleng ba sehlahisoa ka kakaretso.

4. Lekola bioavailability le ho monya ha NAD + phofo

Bioavailability e bolela bokhoni ba 'mele ba ho monya le ho sebelisa metsoako e sebetsang ea tlatsetso. Ha u khetha mofuta oa phofo ea NAD +, nahana ka bioavailability ea sehlahisoa. Batla mefuta e sebelisang lits'ebetso kapa mahlale a tsoetseng pele a ho tsamaisa thepa ho eketsa NAD+ bioavailability. Sena se ka kenyelletsa likarolo tse joalo ka micronization kapa encapsulation, e ka ntlafatsang ho monya ha NAD + 'meleng, qetellong ea eketsa katleho ea eona.

5. Batla lipatlisiso tsa saense le lipatlisiso tsa bongaka

Mefuta e tsebahalang ea phofo ea NAD+ hangata e fana ka lithuto tsa mahlale le tsa bongaka ho ts'ehetsa katleho le polokeho ea lihlahisoa tsa bona. Batla mefuta e tsetelang lipatlisisong le nts'etsopele, kaha sena se bontša boitlamo ba ho hlahisa lihlahisoa tsa boleng bo holimo le tse thehiloeng bopaking. Netefatso ea mahlale e netefatsa hore phofshoana ea NAD+ e entsoe liteko le tlhahlobo e matla, e tiisang boleng ba eona le bohloeki.

Suzhou Myland Pharm & Nutrition Inc. esale e sebetsa khoebong ea tlatsetso ea phepo e nepahetseng ho tloha ka 1992. Ke k'hamphani ea pele naheng ea China ho nts'etsapele le ho rekisa sekhechana sa peo ea morara.

Ka boiphihlelo ba lilemo tse 30 'me e khannoa ke theknoloji e phahameng le leano le ntlafalitsoeng la R&D, k'hamphani e thehile lihlahisoa tse ngata tsa tlholisano mme ea fetoha tlatsetso e ncha ea mahlale a bophelo, ho kopanya tloaelo le khamphani ea lits'ebeletso tsa tlhahiso.

Ho feta moo, Suzhou Myland Pharm & Nutrition Inc. hape ke moetsi ea ngolisitsoeng ke FDA. Lisebelisoa tsa R&D tsa k'hamphani, lisebelisoa tsa tlhahiso, le lisebelisoa tsa tlhahlobo ke tsa sejoale-joale ebile li sebetsa ka bongata mme li ka hlahisa lik'hemik'hale ho tloha ho limiligrama ho isa ho lithane ka sekala, 'me li latela litekanyetso tsa ISO 9001 le litlhaloso tsa tlhahiso ea GMP.

 

P: Li-supplement tsa NAD + li sebelisetsoa eng?
A: tlatsetso ea NAD+ ke tlatsetso ea phepo e nepahetseng e tlatsetsang coenzyme NAD+ (nicotinamide adenine dinucleotide). NAD+ e bapala karolo ea bohlokoa ho metabolism ea matla le tokiso ea lisele ka har'a lisele.
P: Na li-supplement tsa NAD + li hlile lia sebetsa?
A: Lipatlisiso tse ling li fana ka maikutlo a hore li-supplement tsa NAD + li ka thusa ho ntlafatsa metabolism ea matla a cellular le ho liehisa ts'ebetso ea botsofali.
P: Mehloli ea lijo ea NAD + ke efe?
A: Mehloli ea lijo ea NAD+ e kenyelletsa nama, tlhapi, lihlahisoa tsa lebese, linaoa, linate le meroho. Lijo tsena li na le niacinamide le niacin e ngata, tse ka fetoloang NAD + 'meleng.
P: Nka khetha tlatsetso ea NAD + joang?
A: Ha u khetha li-supplement tsa NAD +, ho khothalletsoa hore u qale ho batla keletso ho ngaka kapa setsebi sa phepo e nepahetseng ho utloisisa litlhoko tsa hau tsa phepo le boemo ba bophelo bo botle. Ho feta moo, khetha mofuta o nang le botumo bo botle, hlahloba metsoako ea sehlahisoa le litekanyetso, 'me u latele tataiso ea litekanyetso ho kenyelletsong ea sehlahisoa.

Boitlhotlhollo: Sengoloa sena ke sa tlhaiso-leseling e akaretsang feela 'me ha ea lokela ho nkuoa e le keletso efe kapa efe ea bongaka. Tse ling tsa litaba tsa poso ea blog li tsoa Marang-rang mme ha se setsebi. Sebaka sena sa marang-rang se na le boikarabello ba ho hlophisa, ho hlophisa le ho hlophisa lingoliloeng. Sepheo sa ho fetisa boitsebiso bo bongata ha se bolele hore u lumellana le maikutlo a eona kapa u tiisa bonnete ba litaba tsa eona. Kamehla buisana le setsebi sa tlhokomelo ea bophelo pele u sebelisa li-supplement leha e le life kapa u etsa liphetoho tsamaisong ea tlhokomelo ea bophelo.


Nako ea poso: Aug-05-2024