E le ho phehella bophelo bo botle, batho ba bangata ba lula ba batla litsela tse ncha tsa ho ntlafatsa bophelo ba bona bo botle. Urolithin B phofo ke ntho e 'ngoe e sibolotsoeng e khahlileng tlhokomelo e ngata sechabeng sa bophelo bo botle. Motsoako ona oa tlhaho o bonts'itsoe hore o na le mefuta e mengata ea melemo ea bophelo bo botle, e leng se etsang hore e be tlatsetso e thabisang bophelong ba letsatsi le letsatsi ba mang kapa mang. Ho kenyelletsa phofo ea Urolithin B kemisong ea hau ea letsatsi le letsatsi e ka ba mokhoa o bonolo empa o sebetsa oa ho ts'ehetsa bophelo bo botle le boiketlo ba hau ka kakaretso. Hore na o batla ho ntlafatsa ts'ebetso ea boikoetliso, ho ts'ehetsa botsofali bo botle, kapa ho khothaletsa bophelo bo botle ba mala, motsoako ona oa tlhaho o na le monyetla o moholo oa ho ntlafatsa bophelo ba hau ho tsoa kahare.
Urolithin ke metabolite ea bobeli ea ellagic acid, e tsoang ho ellagitannins.. 'Meleng oa motho, ellagitannins e fetoloa ellagic acid ka limela tsa mala,' me ellagic acid e fetoha urolithin A, urolithin B, urolithin C le urolithin D ka maleng a maholo.
The urolithin precursors ellagic acid le ellagitannins li hlaha ka tlhaho mehloling e meng ea lijo tse kang likharenate, guava, tee, pecans, linate le monokotsoai o kang fragole, li-raspberries tse ntšo le li-blackberries. Urolithin e teng ka plasma e le glucuronide le sulfate conjugates.
Urolithin Bke metabolite e hlahisoang ke gut microbiota ho tloha ellagitannins, polyphenols e fumanoang litholoana le linate tse itseng, tse kang likharenate, fragole, li-raspberries le walnuts. Urolithin B ke sehlahisoa sa ho qetela sa catabolism ea lintho tse ling tsohle tse tsoang ho urolithin. Urolithin B e teng morong joalo ka urolithin B glucuronide.
Mitophagy ke mofuta oa autophagy o thusang ho felisa mitochondria e senyehileng e le hore ba tsebe ho sebetsa hantle. Autophagy e bolela ts'ebetso e akaretsang eo likahare tsa cytoplasmic li senyehang ebe li sebelisoa hape, athe mitophagy ke ho senyeha le ho sebelisoa bocha ha mitochondria.
Nakong ea botsofali, ho fokotseha ha autophagy ke karolo e tlatsetsang ho fokotseha ha mosebetsi oa mitochondrial. Ntle le moo, khatello ea oxidative le eona e ka lebisa ho maemo a tlase a autophagy.
Urolithin B e na le bokhoni ba ho felisa mitochondria e senyehileng ka ho khetha autophagy. Ts'ebetso ena e thusa ho tlosa mitochondria e senyehileng liseleng. Ka ho khothaletsa mitophagy, urolithin B e thusa ho khutlisetsa le ho boloka mitochondria e phetseng hantle, ka hona e ts'ehetsa bophelo bo botle le ts'ebetso ea lisele.
Ho feta moo, khatello ea oxidative e etsahala ha ho na le ho se leka-lekane lipakeng tsa li-radicals tsa mahala le li-antioxidants 'meleng. Li-radicals tsena tse feteletseng tsa mahala hangata li amahanngoa le mafu a mangata a sa foleng, joalo ka lefu la pelo le lefu la tsoekere.
Urolithin B e bonts'a litlamorao tsa antioxidant ka bokhoni ba eona ba ho fokotsa li-radicals tsa mahala, haholo maemo a intracellular reactive oxygen species (ROS), le bokhoni ba eona ba ho thibela lipid peroxidation mefuteng e itseng ea lisele.
Ho feta moo, urolithin e ka thibela li-enzyme tse ling tsa oxidative, ho kenyelletsa monoamine oxidase A le tyrosinase.
Lipatlisiso li bontša hore urolithin B e ka thusa ho lelefatsa nako ea bophelo ka ho khothalletsa botsofali bo botle boemong ba lisele tsa cellular. Ka ho tšehetsa mosebetsi oa mitochondrial le bophelo bo botle ba lisele, urolithin B e na le monyetla oa ho thusa ho finyella bophelo bo bolelele, bo botle.
Kharenate: Kharenate ke e 'ngoe ea mehloli e meholo ea urolithin B. Tholoana ena e matla le e nang le phepo e ntle e na le ellagitannins, e fetoloang urolithin B ke likokoana-hloko tsa mala. Lero la kharenate, peō ea kharenate, esita le likhapetla tsa kharenate li fumanoe e le mehloli e ruileng ea motsoako ona o molemo.
Monokotšoai: Li-monokotsoai tse fapa-fapaneng tse kang fragole, li-raspberries le li-blackberries le tsona li na le ellagitannins, e leng se etsang hore e be mehloli e ka bang teng ea urolithin B. Hase feela litholoana tsena tse monate tse nang le li-antioxidants le livithamine, hape li na le molemo o eketsehileng oa ho tšehetsa tlhahiso ea urolithin B 'meleng. . 'Mele.
Linate: Linate tse ling, tse kang walnuts le pecans, li khethiloe e le mehloli ea ellagitannins, e fetoloang urolithin B ke gut microbiota. Ho kenyelletsa linate tsena lijong tsa hau ho ka thusa ho hlahisa motsoako ona o molemo 'meleng oa hau.
Lijo tse nang le acid e ngata ea ellagic: Lijo tse nang le ellagic acid, tse kang fragole, li-raspberries, li-blackberries le likharenate, li ka boela tsa sebetsa e le mehloli e sa tobang ea urolithin B. Ellagic acid, e leng selelekela sa urolithin B, e ka laoloa ke microbiota ea mala, ho hatisa bohlokoa ba ho kenyelletsa lijo tse nang le asiti e ngata ea ellagic lijong.
Ho kenyelletsa lijo tsena tse nang le urolithin B tse ngata lijong tsa hau ho ka tšehetsa tlhahiso ea motsoako ona o molemo 'meleng, ho fana ka mokhoa oa tlhaho oa ho khothalletsa bophelo bo botle ba lisele le bophelo bo bolelele.
Ho sa tsotellehe boiteko ba rona bo matla ba ho boloka lijo tse leka-lekaneng le tse fapaneng, ha se kamehla ho ka khonehang ho fumana urolithin B 'mele ea rona e hlokang lijo feela. Lintho tse kang kemiso e maphathaphathe, khetho ea lijo, le lithibelo tsa lijo li ka tlatsetsa khaellong ea urolithin B. Tabeng ena, li-supplement tsa urolithin B li ka thusa ho koala lekhalo le ho netefatsa hore 'mele ea rona e fumana limatlafatsi tse hlokahalang ho tšehetsa bophelo bo botle ka kakaretso.
Urolithins ke metabolites e hlahisoang 'meleng ka phetoho ea ellagitannins, e fumanoang litholoana le linate tse itseng. Leha ho le joalo, ha se motho e mong le e mong ea hlahisang urolithin ka katleho, e leng se lebisitseng ho nts'etsopele ea lisebelisoa tsa urolithin ho fana ka motsoako ona o molemo ho bamameli ba bangata.
E 'ngoe ea litšebeliso tsa mantlha tsa li-supplement tsa urolithin ke bokhoni ba tsona ba ho ts'ehetsa bophelo bo botle ba mesifa le ts'ebetso. Lipatlisiso li bontša hore urolithin e ka thusa ho boloka boima ba mesifa le matla, e leng se etsang hore e be tlatsetso e tšepisang bakeng sa batho ba batlang ho tšehetsa ts'ebetso ea 'mele le bophelo bo botle ba mesifa, haholo-holo ha ba ntse ba tsofala.
Ho feta moo, li-urolithin li 'nile tsa amahanngoa le bokhoni ba tsona ba ho khothalletsa bophelo bo botle ba mitochondrial. Hangata mitochondria e bitsoa matla a matla a sele mme e bapala karolo ea bohlokoa tlhahisong ea matla. Lipatlisiso li fumane hore urolithin e ka tšehetsa ts'ebetso ea mitochondrial, e ka bang le liphello tse tebileng ho matla a kakaretso a matla le bophelo bo botle ba lisele.
Ntle le liphello tsa eona ho bophelo bo botle ba mesifa le mitochondrial, urolithin e boetse e ithutoa bakeng sa karolo ea bona e ka bang teng ho khothalletsang bophelo bo bolelele. Boithuto ba mohlala oa liphoofolo bo fana ka maikutlo a hore urolithin e ka thusa ho kenya tšebetsong litsela tse itseng tse amanang le bophelo bo bolelele le botsofali bo botle. Le hoja lipatlisiso tse eketsehileng li hlokahala sebakeng sena, liphello tse ka bang teng li thahasellisa.
Ho feta moo, li-supplement tsa urolithin li fumane tlhokomelo bakeng sa thepa ea tsona e khahlanong le ho ruruha. Ho ruruha ho sa foleng ke sesosa sa mathata a fapaneng a bophelo bo botle, 'me bokhoni ba urolithin ba ho fetola litsela tsa ho ruruha bo ka fana ka mokhoa oa tlhaho oa ho laola ho ruruha' meleng.
Sebaka se seng se khahlang ke bokhoni ba urolithin ho ts'ehetsa bophelo bo botle ba mala. Gut microbiome e bapala karolo ea bohlokoa bophelong bo botle ka kakaretso, 'me li-urolithin li bontšitsoe ho susumetsa sebopeho sa mala a microbiota, e ka bang le litlamorao bakeng sa bophelo bo botle ba tšilo ea lijo le ts'ebetso ea 'mele ea ho itšireletsa mafung.
1. Ja lijo tse ngata tse nang le li-ellagitannins tse ngata
E 'ngoe ea litsela tse molemohali tsa ho eketsa maemo a urolithin 'meleng oa hau ke ho ja lijo tse nang le ellagitannins. Mehloli e meng e metle ea ellagitannins e kenyelletsa likharenate, fragole, li-raspberries, li-blackberries le linate tse kang walnuts le lialmonde. Ka ho kenyelletsa lijo tsena lijong tsa hau, o fa 'mele oa hau li-blocks tseo o li hlokang ho hlahisa urolithin.
2. Tšehetsa bophelo bo botle ba mala
Kaha urolithin e hlahisoa ke baktheria ea mala, ho bohlokoa ho ts'ehetsa microbiome e phetseng hantle le e fapaneng ea maleng. Ho ja lijo tse nang le probiotic tse ngata, joalo ka yoghurt, kefir le meroho e halikiloeng, ho ka thusa ho nts'etsapele kholo ea libaktheria tse molemo tsa mala, tse ntlafatsang tlhahiso ea urolithin. Ho feta moo, ho ja lijo tsa prebiotic joalo ka eiee, konofolo le libanana ho ka fana ka mafura a hlokahalang bakeng sa kholo ea libaktheria tse molemo tsa mala.
3. Nahana ka tlatsetso
Haeba u sa khone ho ja lijo tse nang le urolithin khafetsa, kapa haeba u lakatsa ho eketsa maemo a hau a urolithin, u ka nahana ho nka tlatsetso ea urolithin. Li-supplement tsena li tsoa mehloling ea tlhaho 'me li fana ka litekanyetso tse matla tsa urolithin ho tšehetsa bophelo ba hau. Leha ho le joalo, ho bohlokoa ho buisana le setsebi sa tlhokomelo ea bophelo pele u qala mofuta ofe kapa ofe o mocha oa tlatsetso.
4. Ikoetlise kamehla
Lipatlisiso li bontša hore boikoetliso bo ka boela ba eketsa maemo a urolithin 'meleng. Ho etsa boikoetliso bo tloaelehileng ba 'mele, haholo-holo ho ikoetlisa ka matla a phahameng, ho susumetsa tlhahiso ea urolithin le ho ntlafatsa liphello tsa eona tse molemo mosebetsing oa mesifa le bophelo bo botle ka kakaretso. Ka hona, ho kenyelletsa boikoetliso bo tloaelehileng mosebetsing oa hau oa letsatsi le letsatsi e ka ba mokhoa oa tlhaho oa ho eketsa maemo a urolithin.
5. Boloka lijo tse leka-lekaneng
Ntle le ho ja lijo tse nang le urolithin, ho boloka lijo tse nang le phepo e nepahetseng le tse matlafatsang ho bohlokoa ho tšehetsa bophelo bo botle le bophelo bo botle ka kakaretso. Ho ja litholoana tse fapa-fapaneng, meroho, lijo-thollo, liprotheine tse mafura le mafura a phetseng hantle li fana ka limatlafatsi tse hlokahalang le li-antioxidants tse tšehetsang mekhoa ea tlhaho ea 'mele, ho akarelletsa le tlhahiso ea urolithin.
1. Tlatsetso ea phofo ea Urolithin B
E 'ngoe ea litsela tse bonolo tsa ho kenyelletsa urolithin B ts'ebetsong ea hau ea letsatsi le letsatsi ke ho nkaurolithin Btlatsetso ea phofo. Li-supplement tsena li fumaneha ka mokhoa oa phofo 'me li ka tsoakoa habonolo ho seno seo u se ratang kapa lijong. Ho sa tsotellehe hore na u rata ho e eketsa ho smoothie ea hau ea hoseng, yogurt, kapa feela ho e kopanya le metsi, metsoako ea phofo ea urolithin B e fana ka tsela e bonolo le e sebetsang ea ho etsa bonnete ba hore u fumana tekanyo e tsitsitseng ea metsoako ena ea Molemo.
2. Lijo tse tšetsoeng urolithin B
Tsela e 'ngoe ea ho kenyelletsa urolithin B kemisong ea hau ea letsatsi le letsatsi ke ho ja lijo tse nang le urolithin B. Baetsi ba bang ba lijo ba qalile ho eketsa urolithin B ho lihlahisoa tsa bona, tse kang matla a matla, protheine powders le lino tse tahang. Ka ho kenyelletsa lijo tsena tse kentsoeng urolithin B lijong tsa hau, u ka fumana melemo ea motsoako ona o matla habonolo ntle le ho etsa liphetoho tse kholo mekhoeng ea hau ea ho ja.
3. Lihlahisoa tsa tlhokomelo ea letlalo tse nang le urolithin B e ngata
Ntle le melemo ea eona ea bophelo bo botle ba kahare, urolithin B e boetse e bonts'a ts'episo tšimong ea tlhokomelo ea letlalo. Lik'hamphani tse ling tsa tlhokomelo ea letlalo li se li qalile ho kenya urolithin B lihlahisoa tsa tsona, tse kang li-serum, litlolo le litlolo. Lihlahisoa tsena li etselitsoe ho sebelisa thepa ea antioxidant le anti-inflammatory ea urolithin B ho khothaletsa bophelo bo botle ba letlalo le ho loantša litlamorao tsa botsofali. Ka ho kenyelletsa lihlahisoa tsa tlhokomelo ea letlalo tse nang le urolithin B tse ngata bophelong ba hau ba letsatsi le letsatsi ba tlhokomelo ea letlalo, u ka nka monyetla ka melemo ea eona e ka bang teng bakeng sa letlalo la hau.
4. Urolithin B e tšetseng lino-mapholi
Haeba u natefeloa ke ho noa lino tse khathollang letsatsi lohle, nahana ka ho kenyelletsa lino tse nang le urolithin B kemisong ea hau ea letsatsi le letsatsi. Lik'hamphani tse 'maloa li hlahisitse lino tse tšetsoeng urolithin B, tse kang tee, lero le lino tsa lipapali. Lino tsena li fana ka mokhoa o bonolo le o monate oa ho sebelisa urolithin B ha u ntse u lula u le metsi 'me u khatholohile letsatsi lohle.
5. Urolithin B e matlafatsang phepo e nepahetseng
Bakeng sa ba seng ba ntse ba noa li-supplement tsa phepo e nepahetseng, nahana ka ho batla likhetho tse nang le urolithin B joalo ka motsoako. Ebang ke multivitamin, protein powder, kapa tse ling tse tlatsetsang lijong, ho khetha sehlahisoa se nang le urolithin B ho ka matlafatsa bophelo ba hau ka kakaretso le mekhoa ea bophelo bo botle.
1. Boleng le Bohloeki: Boleng le bohloeki li bohlokoa ha ho tluoa tabeng ea lijo tse tlatsetsang lijong. Batla bahlahisi ba khomarelang litekanyetso tse thata tsa taolo ea boleng le ho sebelisa lisebelisoa tsa boleng bo phahameng ho hlahisa phofo ea Urolithin B. Bahlahisi ba tsebahalang ba tla fana ka litifikeiti tsa tlhahlobo ea mokha oa boraro ho netefatsa bohloeki le matla a lihlahisoa tsa bona.
2. Mokhoa oa tlhahiso: Botsa moetsi ka mokhoa oa ho etsa o sebelisitsoeng. Baetsi ba Powder ba Urolithin B ba molemo ka ho fetisisa ba sebelisa theknoloji e tsoetseng pele ea ho ntša le ho hloekisa ho netefatsa sehlahisoa sa boleng bo phahameng ka ho fetisisa. Hape ba lokela ho latela Mekhoa e Metle ea Tlhahiso (GMP) ho netefatsa polokeho le katleho ea lihlahisoa tsa bona.
3. Lipatlisiso le Ntšetso-pele: Khetha moetsi ea tsetelang lipatlisiso le nts'etsopele hore a lule a le mothating oa ho fokotsa theknoloji ea urolithin B. Baetsi ba ikemiselitseng ho nchafatsa le ntlafatso e tsoelang pele ba na le monyetla oa ho hlahisa phofo ea Urolithin B ea boleng bo holimo le e sebetsang.
4. Tumellano ea Taolo: Netefatsa hore bahlahisi ba latela melao le litekanyetso tsohle tse amehang bakeng sa lijo. Batla litifikeiti tse joalo ka ngoliso ea NSF International, USP, kapa FDA, tse bonts'ang boitlamo ba moetsi ho boleng le polokeho.
5. Maikutlo a Bareki le Bopaki: Batlisisa botumo ba moetsi ka ho bala maikutlo a bareki le bopaki. Bahlahisi ba hlomphehang ba tla ba le maikutlo a matle ho tsoa ho bareki ba khotsofetseng ba boneng melemo ea Urolithin B Powder.
6. Ho Itloaetsa le ho Fetolana: Haeba u na le litlhoko tse khethehileng kapa u hloka foromo e iketselitsoeng, khetha moetsi ea fanang ka likhetho tsa ho feto-fetoha le maemo. Baetsi ba khonang ho iketsetsa phofo ea Urolithin B ho finyella litlhoko tsa hau tse ikhethang ba bontša boitlamo ba ho khotsofatsa bareki.
7. Theko le Bonyane Bonyane Bongata ba Taelo: Le hoja theko e le ntlha ea bohlokoa, ha ea lokela ho ba eona feela ho nahanoa ha u khetha moetsi oa phofo ea Urolithin B. Nahana ka boleng ka kakaretso, ho kenyeletsoa boleng, botšepehi le tšebeletso ea bareki. Hape, botsa ka palo e tlase ea odara mme o netefatse hore e fihlela litlhoko tsa khoebo ea hau.
8. Tšebeletso ea Bareki le Tšehetso: Batla bahlahisi ba fanang ka litšebeletso tse ntle tsa bareki le tšehetso. Sehlopha sa litšebeletso tsa bareki se arabelang le se nang le tsebo se teng ho araba lipotso leha e le life kapa mathata ao u ka bang le 'ona le ho fana ka thuso nakong eohle ea ho reka le ho etsa thepa.
Myland Pharm & Nutrition Inc. esale e sebetsa khoebong ea tlatsetso ea phepo e nepahetseng ho tloha ka 1992. Ke k'hamphani ea pele naheng ea China ho nts'etsapele le ho rekisa sekhechana sa peo ea morara.
Ka boiphihlelo ba lilemo tse 30 'me e khannoa ke theknoloji e phahameng le leano le ntlafalitsoeng la R&D, k'hamphani e thehile lihlahisoa tse ngata tsa tlholisano mme ea fetoha tlatsetso e ncha ea mahlale a bophelo, ho kopanya tloaelo le khamphani ea lits'ebeletso tsa tlhahiso.
Ho feta moo, Myland Pharm & Nutrition Inc. hape ke moetsi ea ngolisitsoeng ke FDA. Lisebelisoa tsa R&D tsa k'hamphani, lisebelisoa tsa tlhahiso, le lisebelisoa tsa tlhahlobo ke tsa sejoale-joale ebile li na le mesebetsi e mengata, 'me li ka hlahisa lik'hemik'hale ho tloha ho limiligrama ho isa ho lithane ka tekanyo,' me li latela litekanyetso tsa ISO 9001 le litlhaloso tsa tlhahiso ea GMP.
P: Urolithin B Powder ke eng le melemo ea eona ea bophelo bo botle?
A: Urolithin B ke motsoako oa tlhaho o tsoang ho ellagic acid, e fumanoang litholoana le linate tse itseng. E 'nile ea ithutoa bakeng sa melemo ea eona e ka' nang ea e-ba teng ho khothalletsa bophelo bo botle ba mitochondrial, ts'ebetso ea mesifa, le ho tsosolosoa ha lisele ka kakaretso.
P: Urolithin B Powder e ka kopanngoa joang le mokhoa oa letsatsi le letsatsi bakeng sa bophelo bo botle?
A: Urolithin B Powder e ka kopanngoa habonolo ka mokhoa oa letsatsi le letsatsi ka ho e kopanya le metsi, smoothies, kapa lino tse ling. Ho bohlokoa ho latela litekanyetso tse khothaletsoang tse fanoeng ke sehlahisoa 'me u buisane le setsebi sa tlhokomelo ea bophelo ha ho hlokahala.
P: Ke lintlha life tse lokelang ho nahanoa ha u khetha Urolithin B Powder?
A: Ha u khetha Urolithin B Powder, ho bohlokoa ho nahana ka lintlha tse kang boleng le bohloeki ba sehlahisoa, litlhahiso tsa litekanyetso, lisebelisoa tse eketsehileng, le botumo ba sehlahisoa.
P: Nka etsa bonnete ba hore boleng le bohloeki ba Urolithin B Powder?
A: Ho netefatsa boleng le bohloeki, sheba lihlahisoa tsa Urolithin B Powder tse lekotsoeng ke motho oa boraro bakeng sa potency le bohloeki, 'me li etsoa mehahong e latelang Mekhoa e Metle ea Tlhahiso (GMP).
Boitlhotlhollo: Sengoloa sena ke sa tlhaiso-leseling e akaretsang feela 'me ha ea lokela ho nkuoa e le keletso efe kapa efe ea bongaka. Tse ling tsa litaba tsa poso ea blog li tsoa Marang-rang mme ha se setsebi. Sebaka sena sa marang-rang se na le boikarabello ba ho hlophisa, ho hlophisa le ho hlophisa lingoliloeng. Sepheo sa ho fetisa boitsebiso bo bongata ha se bolele hore u lumellana le maikutlo a eona kapa u tiisa bonnete ba litaba tsa eona. Kamehla buisana le setsebi sa tlhokomelo ea bophelo pele u sebelisa li-supplement leha e le life kapa u etsa liphetoho tsamaisong ea tlhokomelo ea bophelo.
Nako ea poso: May-10-2024
