Spermidine, activator e matla ea ts'ebetso ea ho nchafatsa lisele, e nkoa e le "seliba sa bocha." Micronutrient ena ka lik'hemik'hale ke polyamine 'me e hlahisoa haholo-holo ke libaktheria tsa mala 'meleng ea rona. Ho phaella moo, spermidine e ka boela ea kenngoa ke 'mele ka ho ja lijo. Lipatlisiso li bontša hore spermidine, ebang e fanoa ka ntle kapa e hlahisoa ke microbiome ea 'mele, e sebetsa ka mokhoa o tlatsanang.
Likhakanyo tsa endogenous spermidine li ka fokotseha ka lilemo, 'me ho ka ba le kamano pakeng tsa sena le ho senyeha ho amanang le lilemo mosebetsing oa' mele. Spermidine e fumanoa lijong tse ngata, 'me grapefruit ke e' ngoe ea lijo tse ruileng ka ho fetisisa tse nang le spermidine. Liphuputso tse ling li fumane hore spermidine ha e liehe feela ho tsofala empa e ka boela ea khothalletsa bophelo bo botle le bophelo bo bolelele. Liphuputso tsena li etsa hore spermidine e be e 'ngoe ea lihlooho tse chesang tsa lipatlisiso tsa morao-rao.
Linthong tse phelang, metsoako ea lisele tsaspermidineho fokotseha ka mokhoa o itšetlehileng ka lilemo; leha ho le joalo, batho ba phetseng hantle ba 90- le centenarians ba na le maemo a spermidine a haufi le a batho ba bacha (ba lilemo tse mahareng). Phuputso ea epidemiological e tlaleha kamano e ntle pakeng tsa ho noa spermidine le bophelo bo botle ba batho. Barupeluoa ba 829 ba lilemo tse 45-84 ba ile ba lateloa ka lilemo tse 15. Ho kenngoa ha spermidine ho hakanngoa lilemo tse ling le tse ling tsa 5 ho latela lipotso tsa makhetlo a lijo. Liphuputso li fumane hore batho ba nang le spermidine e ngata ba fokotsa litekanyetso tsa kankere le lefu la pelo 'me ba amahanngoa le bophelo bo ntlafetseng.
◆ Mokhoa o thibelang botsofali
Ka 2023, "Cell" e phatlalalitse sengoloa hore ho na le matšoao a 12 a botsofali, ho kenyeletsoa ho se tsitse ha genome, telomere attrition, liphetoho tsa epigenetic, tahlehelo ea protheine homeostasis, macroautophagy ho se khonehe, mathata a ho utloa limatlafatsi, ho se sebetse ha mitochondrial, le senescence ea cellular. Ho felloa ke matla ha lisele tsa stem, puisano e fetotsoeng lipakeng tsa lisele, ho ruruha ho sa foleng, le dysbiosis.
● Induction ea autophagy
Hona joale, ho kenngoa ha autophagy ho nkoa e le mokhoa o ka sehloohong oo spermidine e liehisang botsofali. Liphuputso li fumane hore spermidine e etsa hore ho be le dephosphorylation ea protheine kinase B, e leng se etsang hore ho tsamaisoe forkhead box transcription factor O (FoxO) ho ea khubung, e leng se fellang ka ho eketseha ha mongolo oa FoxO target gene autophagy microtubule-associated protein light chain 3 (LC3). ). Khothaletsa autophagy.
Ho phaella moo, spermidine e fumanoe e thusa ho lieha ho tsofala ha lisele tsa likokoana-hloko tsa basali tse bakoang ke khatello ea oxidative le ho boloka tsoalo ea basali. Phuputso ea kliniki e nkileng selemo e fumane hore maemo a peō ea botona a matlafalitsoe ho baithaopi ba batona ba phetseng hantle ha ba ne ba fuoa spermidine; boithutong ba 2022, phuputso e shebile bakuli ba 377 ba acute myocardial infarction (AMI). ba fumane hore batho ba nang le maemo a phahameng a spermidine maling a bona ba ne ba e-na le menyetla e molemo ea ho phela ho feta bakuli ba lefu la pelo ba nang le maemo a tlaase a spermidine; Koranta ea 2021 e fumane hore ho ja lijo tse phahameng tsa spermidine Ho na le kamano pakeng tsa litekanyetso le kotsi e fokotsehileng ea bokooa ba kelello ho batho, e ruisang boko haholo ho ntlafatsa kutloisiso le ho thibela mafu a tloaelehileng a boko a amanang le lilemo.
●Lieha ho tsofala ha telomere
Botsofali bo baka mathata a mangata a limolek'hule, lisele le 'mele, ho kenyelletsa le ho hloleha ha pelo, neurodegeneration, maladaptation ea metabolism, telomere attrition, le tahlehelo ea moriri. Hoa thahasellisa hore boemong ba limolek'hule, bokhoni ba ho susumetsa autophagy (mochine o ka sehloohong oa ts'ebetso ea spermidine) bo fokotseha ka lilemo, ketsahalo e teng mefuteng e mengata ea likokoana-hloko 'me ho nahanoa hore e amana haufi-ufi le botsofali. .
● Antioxidant le anti-inflammatory liphello
Khatello ea oxidative ke ntho ea bohlokoa e lebisang botsofaling ba lisele le tšenyo. Spermidine e na le thepa ea antioxidant. Bafuputsi ba ile ba fepa litoeba exogenous spermidine ka likhoeli tse tharo mme ba bona liphetoho mae a bomme. Ka mor'a phekolo ea spermidine, sehlopha, palo ea li-atrophic follicles (follicles e senyehileng) e fokotsehile haholo, ts'ebetso ea antioxidant ea enzyme e ile ea eketseha, 'me maemo a malondialdehyde (MDA) a fokotseha, a ka fokotsang mefuta ea oksijene e sebetsang (ROS), e bontšang ho fokotseha ha khatello ea oxidative ho spermidine. - sehlopha sa phekolo.
Ho ruruha ho sa foleng ho bonahala ho ke ke ha qojoa ha re ntse re tsofala. Ho eketseha ha spermidine ho thusa ho susumetsa tlhahiso ea li-cytokine tse thibelang ho ruruha ha li ntse li fokotsa tlhahiso ea li-cytokine tse thibelang ho ruruha. Liphuputso tsa morao-rao li bontša hore spermidine e boetse e ntlafatsa thepa ea anti-inflammatory ea macrophages.
●Thibela ho tsofala ha lisele tsa stem
Spermidine e khothalletsa ts'ebetso ea mitochondrial le tlhahiso ea keratin liseleng tsa epithelial stem, ho netefatsa ho tsosolosoa ha mesifa le moriri.
Spermidineke motsoako oa polyamine ka tlhaho o fumanoang linthong tse phelang. Kaha ke motsoako oa polyamine, o na le lihlopha tse ngata tsa amino (-NH2). Lihlopha tsena li boetse li e fa e ikhethang le ea bohlokoa Tatso ea lebitso.
Ke hantle ka lebaka la lihlopha tsena tsa amino hore e khona ho sebelisana le mefuta e fapaneng ea li-biomolecule le ho etsa mesebetsi ea eona ea 'mele ka har'a lisele. Ka mohlala, e phetha karolo ea bohlokoa khōlong ea lisele, karohano, taolo ea liphatsa tsa lefutso, le khahlanong le botsofali.
Khahlanong le botsofali
Boemo ba spermidine ke letšoao le bontšang tekanyo ea botsofali ba 'mele. Ha 'mele o ntse o tsofala, karolo ea spermidine' meleng le eona ea fokotseha. Liphuputso li bontšitse hore spermidine e ka liehisa botsofali ba lisele tse kang lisele tsa tomoso le lisele tsa mammalian, le ho lelefatsa bophelo ba likokoana-hloko tse se nang mokokotlo tse kang Drosophila melanogaster le Caenorhabditis elegans le litoeba.
Hona joale, ho kenngoa ha autophagy ho ipakile e le e 'ngoe ea mekhoa e ka sehloohong eo spermidine e liehisang botsofali le ho lelefatsa nako ea bophelo. Liphuputso li bontšitse hore ka mor'a ho tlosa liphatsa tsa lefutso tse hlokahalang bakeng sa autophagy tomosong ea botsofali, Drosophila le lisele tsa mammalian tse hōlileng, liphoofolo tsena tsa mohlala ha lia ka tsa phela nako e telele ka mor'a phekolo ea spermidine. Ho phaella moo, spermidine e boetse e sebetsa ka mekhoa e kang ho fokotsa histone acetylation.
Antioxidant
Spermidine e na le mesebetsi ea bohlokoa ea li-antioxidant, 'me e ka ba le litlamorao tse ngata tse thibelang botsofali ka thepa ea eona ea antioxidant. Liphuputso li bontšitse hore spermidine e ka fokotsa haholo maemo a oxidant malondialdehyde le ho eketsa maemo a antioxidant a fokotsehileng glutathione bokong ba likhoto.
Tlatsetso ea Spermidine e boetse e ntlafalitse ts'ebetso ea li-elektronike tsa ketane ea lipalangoang ho mitochondria ea boko bo tsofetseng, e bonts'ang matla a eona a antioxidant maemong a mitochondrial. Spermidine e fokotsa tšenyo ea methapo e bakoang ke botsofali bo bakoang ke khatello ea oxidative ka ho laola autophagy, litekanyetso tsa antioxidant le ho fokotsa neuroinflammation.
Liphuputso li fumane hore spermidine e sireletsa tšenyo ea lisele tse bakoang ke H2O2 ka ho thibela keketseho ea Ca2 + liseleng tsa epithelial tsa retinal pigment.
Anti-inflammatory
Spermidine e na le phello e ntle ea ho thibela ho ruruha, 'me mochine oa eona o amana le ho thibela tlhahiso ea lintho tse thibelang ho ruruha, ho khothalletsa tlhahiso ea lintho tse thibelang ho ruruha, le ho ama polarization ea macrophages.
Boithuto bo fumane hore spermidine e ka fokotsa maemo a pro-inflammatory factor joalo ka interleukin 6 le tumor necrosis factor serum ea litoeba tse nang le collagen-induced ramatiki, ea eketsa boemo ba IL-10, e thibela polarization ea M1 macrophages ka har'a lisele tsa synovial. , le ho fokotsa kotsi ea ho tšoaroa ke ramatiki. Lisele tsa synovial tsa mouse li ile tsa ata 'me lisele tsa ho ruruha li kenngoa, li bontša liphello tse ntle tse khahlanong le ho ruruha.
Ntlafatsa temoho
Ha palo ea batho e ntse e hōla, mathata a kelello a amanang le lilemo a ntse a eketseha. Spermidine, joalo ka e inducer autophagy, e bontšitsoe hore e na le phello e matlafatsang ho fokotseha ha kelello.
Lipatlisiso li bontša hore lintsintsing tse tsofalang tsa litholoana, maemo a spermidine a fokotseha, e leng se tsamaeang le ho fokotseha ha bokhoni ba ho hopola. Tlatsetso ea Spermidine e feptjoang ho lintsintsi e fokotsa ho senyeha ha mohopolo ho lintsintsi tse tsofalang ka ho thibela liphetoho tsa sebopeho le ts'ebetso ts'ebetsong ea presynaptic e bakoang ke maemo a phahameng a liprotheine tsa synaptic le liprotheine tse tlamang.
Spermidine ka lijong e ka feta mokoallong oa mali le boko ba litoeba, ea eketsa phefumoloho ea mitochondrial ka har'a lisele tsa neuron ea mouse, le ho ntlafatsa ts'ebetso ea kelello ea litoeba. Motheong oa liteko tsa liphoofolo, liphuputso tse ling tsa batho li boetse li pakile hore spermidine e amana haufi-ufi le tsebo.
Sireletsa pelo le methapo
Spermidine e ka sireletsa bophelo bo botle ba pelo 'me e na le liphello tse ngata tse kang ho thibela botsofali ba pelo, ho fokotsa khatello e phahameng ea mali le ho liehisa ho hloleha ha pelo. Liphuputso li bontšitse hore tlatsetso ea spermidine e ka matlafatsa autophagy ea pelo le mitophagy ho litoeba, ea ba le phello ea pelo le ho liehisa botsofali ba pelo.
Ho litoeba tse tsofetseng, tlatsetso ea spermidine ea lijo e ntlafatsa boleng ba mochini le lisebelisoa tsa metabolic tsa cardiomyocyte, ka hona, e lelefatsa bophelo le ho thibela hypertrophy ea pelo e bakoang ke lilemo le ho satalla. Lithuto tsa Epidemiological ho batho li fana ka maikutlo a hore spermidine e na le ts'ireletso e ts'oanang le bophelo bo botle ba pelo ea motho. Ho kenngoa ha spermidine lijong tsa batho ho amana ka tsela e fapaneng le lefu la pelo. Lintho tsena tsa spermidine li bula mekhoa e mecha ea ho phekola mafu a pelo.
Boemo ba hona joale ba nts'etsopele le ts'ebeliso ea spermidine
Spermidine ke polyamine e hlahang ka tlhaho. Lintho tsa 'mele tsa spermidine ke tsa tlhaho, li sebetsa hantle, li bolokehile ebile ha li na chefo. Ka boithuto bo tebileng ba litlamorao tsa 'mele oa spermidine, e bonts'itse boleng ba ts'ebeliso ea bohlokoa mafapheng a mangata joalo ka meriana, lijo tsa bophelo bo botle, temo, litlolo joalo-joalo.
Moriana
Spermidine e na le litlamorao tse fapaneng tsa 'mele joalo ka anti-botsofali, anti-inflammatory, anti-cancer, le ho ntlafatsa temoho. E ka sebelisoa bakeng sa thibelo le kalafo ea osteoarthritis, tšenyo ea lisele tsa methapo, lefu la pelo le mafu a mang. Spermidine e sebelisoa lits'ebetsong tsa bongaka. Kalafo ea mafu e na le menyetla e metle ea tsoelo-pele.
Lijo tsa bophelo bo botle
Ho sebelisa "spermidine" le "lisebelisoa tse sebetsang tsa lijo" e le mantsoe a bohlokoa ho etsa lipatlisiso tsa data ho li-database tse ngata, liphetho li bontša hore "spermidine" kapa "spermine" e hlalosoa e le lisebelisoa tse sebetsang tsa lijo, 'me spermidine e rekisitsoe' marakeng ka spermidine. . Sejo sa bophelo bo botle se nang le amine joalo ka ntho e ka sehloohong e tala.
Lihlahisoa tsa bophelo bo botle tse amanang le Spermidine li na le mesebetsi e fapaneng 'me li sebelisoa haholo ka mefuta e sa tšoaneng, ho akarelletsa matlapa, phofo le mefuta e meng ea litekanyetso. E na le mesebetsi ea ho thibela botsofali, ho ntlafatsa boroko, le ho ntlafatsa tšireletso ea 'mele; phofo ea tlhaho ea spermidine e ntšitsoeng kokoana ea koro e tiisa bohloeki bo phahameng le mosebetsi o phahameng oa spermidine.
Temothuo
Joalo ka taolo ea kholo ea semela, ts'ebeliso ea kantle ea spermidine e ka fokotsa tšenyo ea limela e bakiloeng ke khatello ea maikutlo joalo ka mocheso o phahameng oa oxidation, mocheso o tlase le serame, hypoxia, letsoai le phahameng, komello, likhohola le ho kenella, 'me e phetha karolo ea bohlokoa kholong ea semela. . Karolo ea eona ea bohlokoa temong e hohetse tlhokomelo butle-butle. Exogenous spermidine e ka fokotsa phello e thibelang ea khatello ea komello kholong ea mabele a monate le ho matlafatsa mamello ea komello ea lipeo tse monate tsa mabele. Ho ipapisitsoe le karolo ea bohlokoa ea spermidine kholong ea semela, e na le litokelo tse ngata tsa boqapi tšimong ea temo. Ho etsa lipatlisiso le ho nts'etsapele lihlahisoa tsa temo tsa spermidine le ho khothaletsa tšebeliso ea spermidine tšimong ea temo ke tsa bohlokoa haholo ntlafatsong ea temo.
Cosmetic
Spermidine e na le antioxidant, anti-botsofali, le ho khothaletsa litlamorao tsa autophagy, hape ke thepa e tala ea litlolo. Hajoale, ho na le lihlahisoa tsa tlhokomelo ea letlalo joalo ka tranelate e thibelang botsofali ea spermidine le lebese la spermidine essence 'marakeng. Ho feta moo, spermidine e na le litokelo tse ngata tsa lipatlisiso lefapheng la litlolo ho pota lefatše, tse kenyelletsang ho soeufala, ho thibela botsofali ba letlalo, le ntlafatso ea masoba a sefahleho. Lipatlisiso tse tebileng mabapi le mokhoa oa ts'ebetso ea spermidine, ho ntlafatsa liforomo tsa eona tsa kopo, le ho hlahloba tšireletseho le litla-morao li lebeletsoe ho fa bareki mekhoa e sireletsehileng le e sebetsang haholoanyane ea tlhokomelo ea letlalo.
Ho batho, maemo a potolohang aspermidine hangata li maemong a tlase a micromolar, haholo-holo ka lebaka la litlamorao tsa lijo tse amanang le spermidine ka kakaretso. Leha li bontša liphapang tse matla lipakeng tsa batho. Leha ho le joalo, ha re ntse re hōla, palo ea spermidine liseleng tsa 'mele ea rona ea fokotseha. Exogenous spermidine supplementation e fetola liphetoho tse mpe tse amanang le lilemo le ho liehisa botsofali.
● Prescine / spermine metabolism
Liseleng tsa mammalian, spermidine e hlahisoa ho tsoa ho precursor putrescine (ka boeona e hlahisoa ho tsoa ho ornithine) kapa ka ho senyeha ha oxidative ea spermine.
● Gut microbiota
Intestinal microbiota ke mohloli oa bohlokoa oa motsoako oa spermidine. Ho litoeba, khatello ea spermidine ka har'a lumen ea mala e bontšitsoe hore e itšetlehile ka ho toba ho colonic microbiota.
●Mehloli ea lijo
Spermidine e kenngoa lijong e ka kenngoa ka potlako ho tloha mala 'me ea ajoa' meleng, kahoo ho ja lijo tse nang le spermidine ho ka thusa ho eketsa maemo a spermidine 'meleng.
●Spermidine supplements
Lihlahisoa tsa bophelo bo botle tse amanang le Spermidine li na le mesebetsi e fapaneng 'me li sebelisoa haholo ka mefuta e sa tšoaneng, ho akarelletsa matlapa, phofo le mefuta e meng ea litekanyetso. E na le mesebetsi ea ho thibela botsofali, ho ntlafatsa boroko, le ho ntlafatsa tšireletso ea 'mele; phofo ea tlhaho ea spermidine e ntšitsoeng kokoana ea koro e tiisa bohloeki bo phahameng le mosebetsi o phahameng oa spermidine.
Bohloeki le Boleng
Ha u reka phofo ea spermidine, ke habohlokoa ho etelletsa pele bohloeki le boleng. Batla lihlahisoa tse entsoeng ka metsoako ea boleng bo holimo 'me li lekoa ka matla bakeng sa ho hloeka le ho sebetsa hantle. Ka nepo, khetha lihlahisoa tse entsoeng lifemeng tse latelang Mekhoa e Metle ea Tlhahiso (GMP) ho netefatsa boleng le polokeho.
Bioavailability
Bioavailability e bolela bokhoni ba 'mele ba ho monya le ho sebelisa ntho. Ha u khetha phofo ea spermidine, nahana ka bioavailability ea sehlahisoa. Batla foromo e etselitsoeng ho monya hantle, kaha sena se tla etsa bonnete ba hore 'mele oa hau o ka sebelisa spermidine ka nepo ho fana ka melemo ea eona ea bophelo bo botle.
Tlhahlobo ea ponaletso le ea motho oa boraro
Mokhoa oa ho fumana le ho hlahisa phofo ea spermidine e tsebahalang e lokela ho ba pepeneneng. Batla lihlahisoa tse fanang ka lintlha tse qaqileng mabapi le ho fumana metsoako ea tsona le ho etsoa ha lihlahisoa tsa tsona. Ntle le moo, tlhahlobo ea motho oa boraro ke lilaboratori tse ikemetseng e netefatsa boleng ba sehlahisoa le bohloeki. Batla lihlahisoa tse lekiloeng ke mekhatlo ea batho ba bang ho netefatsa ts'ebetso le polokeho ea tsona.
Tekanyo le boholo ba ho sebeletsa
Ha u reka phofo ea spermidine, nahana ka litekanyetso le boholo ba ho sebeletsa tse lumellanang hantle le litlhoko tsa hau. Lihlahisoa tse ling li ka fana ka tekanyo e phahameng ea spermidine ka ho sebeletsa, ha lihlahisoa tse ling li ka fana ka tekanyo e tlaase. Ke habohlokoa ho fumana tekanyo e nepahetseng ho latela lipakane tsa hau tsa bophelo bo botle le ho buisana le setsebi sa tlhokomelo ea bophelo ha ho hlokahala.
Recipe le lisebelisoa tse eketsehileng
Spermidine phofo e fumaneha ka mefuta e fapaneng ea litekanyetso, ho kenyelletsa capsule, phofo kapa foromo ea metsi. Nahana hore na ke sebopeho sefe se lumellanang hantle le mokhoa oa hau oa bophelo le likhetho tsa hau. Ho phaella moo, lihlahisoa tse ling li ka 'na tsa e-na le lisebelisoa tse eketsehileng ho ntlafatsa liphello tsa spermidine kapa ho ntlafatsa tatso ea eona. Ela hloko lisebelisoa life kapa life tse ekelitsoeng 'me u netefatse hore li kopana le khetho ea hau ea lijo le lithibelo.
Maikutlo a bareki le botumo
Pele o reka, iphe nako ea ho etsa lipatlisiso ka botumo ba mofuta ona le ho bala maikutlo a bareki. Batla maikutlo a batho ba sebelisitseng sehlahisoa sena ho fumana leseli mabapi le katleho ea sona le litla-morao life kapa life tse ka bang teng. Lihlahisoa tse nang le botumo bo botle le litlhahlobo tse ntle tsa bareki li ka fana ka phofo ea spermidine e tšepahalang le ea boleng bo holimo.
Theko khahlano le boleng
Le hoja theko e sa lokela ho ba eona feela ntho e etsang qeto, ho bohlokoa ho nahana ka boleng ba sehlahisoa mabapi le theko ea sona. Bapisa litšenyehelo tsa phofo e fapaneng ea spermidine 'me u nahane ka boleng, bohloeki le melemo e meng ea sehlahisoa ka seng. Ho kenya chelete ka phofo ea boleng bo phahameng ea spermidine ho ka fana ka melemo e mengata ea bophelo bo botle.
Suzhou Myland Pharm's Spermidine Powder—Setlatsi sa lijo tsa boleng bo holimo
Ho Suzhou Myland Pharm, re ikemiselitse ho fana ka lihlahisoa tsa boleng bo holimo ka litheko tse ntle. Phofo ea rona ea spermidine e lekoa ka matla bakeng sa bohloeki le potency, ho netefatsa hore u fumana tlatsetso ea boleng bo phahameng eo u ka e tšepang. Hore na o batla ho ts'ehetsa bophelo bo botle ba lisele, ho matlafatsa sesole sa hau sa 'mele kapa ho ntlafatsa bophelo bo botle ka kakaretso, phofo ea rona ea spermidine ke khetho e phethahetseng.
Ka boiphihlelo ba lilemo tse 30 'me e khannoa ke thekenoloji e phahameng le maano a R&D a ntlafalitsoeng haholo, Suzhou Myland Pharm e hlahisitse lihlahisoa tse ngata tsa tlholisano mme e fetohile tlatsetso e ncha ea mahlale a bophelo, tlhahiso ea moetlo le khamphani ea lits'ebeletso tsa tlhahiso.
Ntle le moo, Suzhou Myland Pharm le eona ke moetsi ea ngolisitsoeng ke FDA. Lisebelisoa tsa R&D tsa k'hamphani, lisebelisoa tsa tlhahiso, le lisebelisoa tsa tlhahlobo ke tsa sejoale-joale ebile li na le mesebetsi e mengata, 'me li ka hlahisa lik'hemik'hale ho tloha ho limiligrama ho isa ho lithane ka tekanyo,' me li latela litekanyetso tsa ISO 9001 le litlhaloso tsa tlhahiso ea GMP.
P: Phofo ea spermidine ke eng hona e amana joang le botsofali?
A: Spermidine ke motsoako oa tlhaho oa polyamine o fumanoang lijong tse fapa-fapaneng le 'mele oa motho. Lipatlisiso li fana ka maikutlo a hore spermidine e ka ba le liphello tse khahlanong le botsofali ka ho khothalletsa bophelo bo botle ba lisele le bophelo bo bolelele.
P: Phofo ea spermidine e sebetsa joang ho loantša botsofali?
A: Ho lumeloa hore Spermidine e kenya tšebetsong tšebetso ea cellular e bitsoang autophagy, e thusang ho tlosa lisele tse senyehileng le ho khothaletsa nchafatso ea lisele tse phetseng hantle. Ho nahanoa hore mokhoa ona o phetha karolo ea bohlokoa ho fokotsa ho tsofala.
P: Ke melemo efe e ka bang teng ea ho nka phofo ea spermidine bakeng sa botsofali?
A: Liphuputso tse ling li bontšitse hore tlatsetso ea spermidine e ka thusa ho ntlafatsa bophelo bo botle ba pelo, ts'ebetso ea boko le bophelo bo bolelele ka kakaretso. E kanna ea ba le melemo e ka bang teng bakeng sa bophelo bo botle ba letlalo le ts'ebetso ea 'mele ea ho itšireletsa mafung.
P: Nka etsa bonnete ba hore boleng ba phofo ea spermidine ha ke e reka Inthaneteng?
A: Batla morekisi ea nang le botumo bo botle le ea ikemetseng ea nang le rekoto ea ho fana ka lijo tsa boleng bo holimo. Sheba maikutlo a bareki le lintlha ho lekanya ho tšepahala ha mofani oa thepa.
Boitlhotlhollo: Sengoloa sena ke sa tlhaiso-leseling e akaretsang feela 'me ha ea lokela ho nkuoa e le keletso efe kapa efe ea bongaka. Tse ling tsa litaba tsa poso ea blog li tsoa Marang-rang mme ha se setsebi. Sebaka sena sa marang-rang se na le boikarabello ba ho hlophisa, ho hlophisa le ho hlophisa lingoliloeng. Sepheo sa ho fetisa boitsebiso bo bongata ha se bolele hore u lumellana le maikutlo a eona kapa u tiisa bonnete ba litaba tsa eona. Kamehla buisana le setsebi sa tlhokomelo ea bophelo pele u sebelisa li-supplement leha e le life kapa u etsa liphetoho tsamaisong ea tlhokomelo ea bophelo.
Nako ea poso: Aug-28-2024
