Na u leetong la bophelo bo botle 'me u batla litlhare tse tla matlafatsa bophelo ba hau ba' mele le kelello? Se shebe hole ho feta li-supplement tsa 7,8-dihydroxyflavone. 7,8-Dihydroxyflavone ke flavonoid e fumanoang limela tse itseng 'me e ithutile melemo ea eona ea bophelo bo botle. Lipatlisiso li bontša hore 7,8-dihydroxyflavone e na le neuroprotective, anti-inflammatory, and antioxidant properties, e leng se etsang hore e be tlatsetso e kholo ea bophelo bo botle. Haeba u batla ho nka leeto la hau la bophelo bo botle ho ea boemong bo latelang, nahana ka ho kenyelletsa tlatsetso ea 7,8-dihydroxyflavone tšebetsong ea hau ea letsatsi le letsatsi.
Joale hantle-ntle ke eng7,8-dihydroxyflavone? 7,8-DHF ke flavonoid e fumanoang limela le meroho e meng. E ile ea sibolloa ha ho ntse ho batloa molek'hule e etsisang tšebetso ea boko-derived neurotrophic factor (BDNF), molek'hule e nyenyane e kenyang mokelikeli o itseng o bitsoang tropomyosin-related kinase B (TrkB) hobane peptide e sebetsa ho receptor ena, e bitsoang boko- derived neurotrophic factor (BDNF), e ke ke ea sebelisoa ka lebaka la malabsorption ke boko.
7,8-DHF e fumanoe e le setšoantšo se matla sa BDNF, se sebetsang ka mokhoa o ts'oanang ho TrkB. Sena se bolela hore 7,8-DHF e ka hlahisa litlamorao tse ts'oanang bokong joalo ka BDNF, 'me ho ka boleloa hore e ka ba molemo haholoanyane kalafong ka lebaka la ho monya ha eona hantle le bokhoni ba ho tšela mokoallo oa mali bokong.
Ka lebaka la bokhoni ba eona ba ho susumetsa li-receptor tsa TrkB, li-receptor tsa TrkB li bapala karolo ea bohlokoa kholong le ho phela ha li-neurone bokong. Ha li-receptor tsa TrkB li sebetsa, li-neurone li na le ho ba le kholo le ts'ireletso. Khōlo ena e atisa ho ama li-dendrites tsa li-neurone, tse atolohelang ho li-synapse ho buisana le li-neurone tse latelang, 'me 7,8-DHF e bontšitsoe ho khothalletsa kholo ea li-dendrite tsena hore e be li-synapses, ho thusa ho tsosolosa liphoofolo Puisano pakeng tsa methapo ea kutlo ka mohlala oa kutloisiso. fokotseha.
Liphuputso tse ngata li fana ka maikutlo a hore 7,8-DHF e ka ba le monyetla oa ho ntlafatsa ho ithuta le mohopolo, ho thibela mafu a neurodegenerative, esita le ho tšehetsa maikutlo le bophelo bo botle ba maikutlo. Liphuputso tsena li entse hore ho be le thahasello ho li-supplement tsa 7,8-dihydroxyflavone e le mekhoa e meng ea tlhaho ea ho tšehetsa bophelo bo botle ba boko.
Batho ba bangata ba fetohela ho li-supplement tsa 7,8-dihydroxyflavone ho ts'ehetsa ts'ebetso ea bona ea kelello, haholo ha ba tsofala kapa ba tobana le mathata a amanang le mohopolo le mohopolo. Khopolo eaho sebelisa metsoako ea tlhaho ho ts'ehetsa bophelo bo botle ba boko ho khahla haholo ho ba khethang mokhoa oa tlhaho, o akaretsang oa bophelo bo botle.
E 'ngoe ea mekhoa e ka sehloohong ea ts'ebetso ea 7,8-dihydroxyflavone ke bokhoni ba eona ba ho kenya tšebetsong tsela ea pontšo ea tropomyosin receptor kinase B (TrkB). TrkB ke receptor bakeng sa neurotrophic factor brain-derived neurotrophic factor (BDNF) mme e bapala karolo ea bohlokoa kholong, ho phela le ts'ebetsong ea li-neurone lits'ebetsong tsa methapo tse bohareng le tsa peripheral. Ts'ebetso ea TrkB receptor ka 7,8-dihydroxyflavone e lebisa ho phosphorylation ea sebaka sa eona sa intracellular, e leng se etsang hore ho be le letoto la liketsahalo tse bontšang matšoao a tlaase, qetellong li khothalletsa ho pholoha ha neuronal, kholo le phapang.
Boithuto bo bontšitse hore 7,8-dihydroxyflavone e bonts'a litlamorao tsa neuroprotective mefuteng e mengata ea mafu a neurodegenerative, joalo ka lefu la Alzheimer's le Parkinson's. Ka ho kenya ts'ebetsong tsela ea pontšo ea TrkB, 7,8-dihydroxyflavone e ntlafatsa bophelo ba li-neurone, e ba sireletsa khatellong ea oxidative le ho ruruha, 'me e khothalletsa ho thehoa ha likhokahano tse ncha tsa synaptic, tse ka fokotsang kapa esita le ho khutlisetsa morao ho fokotseha hona. tsoelo-pele ea lefu lena.
Ntle le litlamorao tsa neuroprotective, 7,8-dihydroxyflavone e fumanoe e na le litlamorao tse tšoenyang. Liphello tsena ho nahanoa hore li na le matla a ho matlafatsa liphello tsa BDNF bokong, ka tsela eo ho matlafatsa polasetiki ea neuronal le ho ba le botsitso ha ho tobane le khatello ea kelello le mathata a maikutlo. Ho feta moo, liphuputso tsa pele ho kliniki li bonts'itse hore 7,8-dihydroxyflavone e ka ntlafatsa ts'ebetso ea ho ithuta le mohopolo, ea phahamisa monyetla oa ts'ebeliso ea eona ho alafong mathata a kelello a amanang le maemo a joalo ka 'dementia' le kotsi e sithabetsang ea boko.
Bopaki bo bocha bo fana ka maikutlo a hore e kanna ea ba le litlamorao ho lisele le litho tse ling. Ka mohlala, 7,8-dihydroxyflavone e bontšitsoe hore e na le li-anti-inflammatory, antioxidant thepa mefuteng e sa tšoaneng ea lisele le liphoofolo, e fana ka maikutlo a bokhoni ba eona ba ho phekola mafu a sa foleng a ho ruruha.
E 'ngoe ea limela tse nang le 7-8 dihydroxyflavonoids ke Tridax procumbens, e tsejoang ka hore ke daisy kapa Tridax daisy. Semela sena se tsoa libakeng tsa tropike 'me esale se sebelisoa meriana ea Ayurvedic bakeng sa melemo ea eona e mengata ea bongaka. Bafuputsi ba fumane hore Tridax procumbens e na le 7 ho 8 dihydroxyflavonoids, e tsosang thahasello ea ho hlahloba melemo ea eona ea bophelo bo botle.
Semela se seng se nang le 7-8 dihydroxyflavone ke semela sa Godmania aesculifolia, se hlahetseng Mexico. Semela sena se sebelisoa meriana ea setso ea Mexico bakeng sa thepa ea eona e khahlanong le ho ruruha le ea analgesic. Lipatlisiso li bontša hore Godmania aesculifolia e na le 7-8 dihydroxyflavone, e leng se hlahisitseng lipatlisiso tse eketsehileng mabapi le tšebeliso ea eona ea phekolo.
Ho phaella ho Tridax procumbens le Godmania aesculifolia, limela tse ling tse 'maloa ho nahanoa hore li na le 7-8 dihydroxyflavonoids, le hoja lipatlisiso tse ling li hlokahala ho netefatsa boteng ba tsona limela tsena. Tsena li kenyelletsa fisetin le acacia shrub.
1. Ntlafatso ea Kelello: E 'ngoe ea melemo e tsebahalang haholo ea li-supplement tsa 7,8-dihydroxyflavone ke bokhoni ba eona ba ho ntlafatsa ts'ebetso ea kelello. Lipatlisiso li bontša hore 7,8-DHF e thusa ho ntlafatsa mohopolo, ho ithuta le ho sebetsa ha boko ka kakaretso. Ka ho khothaletsa kholo ea lisele tse ncha tsa boko le ho matlafatsa likhokahano lipakeng tsa li-neurone tse teng, li-supplement tsa 7,8-dihydroxyflavone li ka thusa ho ts'ehetsa bophelo bo botle ba boko ba hau le bokhoni ba kelello.
2.Mood Support: Ho phaella melemo ea kutloisiso, li-supplement tsa 7,8-dihydroxyflavone li bontšitsoe hore li na le phello e ntle maikutlong. Lipatlisiso li bontša hore 7,8-DHF e ka thusa ho laola li-neurotransmitters tse amanang le maikutlo bokong, tse kang dopamine le serotonin, tse phethang karolo ea bohlokoa taolong ea maikutlo. Ka ho tšehetsa li-neurotransmitters tsena, li-supplement tsa 7,8-dihydroxyflavone li ka thusa ho ntlafatsa maikutlo le bophelo bo botle ba maikutlo.
3. Liphello tsa Neuroprotective: Li-supplement tsa 7,8-dihydroxyflavone le tsona li fumanoe li na le lisebelisoa tsa neuroprotective. Sena se bolela hore li ka thusa ho sireletsa boko le tsamaiso ea methapo tšenyong e bakiloeng ke khatello ea oxidative, ho ruruha le lits'ebetso tse ling tse kotsi. Ka ho ts'ehetsa bophelo bo botle le ts'ebetso ea lisele tsa boko, li-supplement tsa 7,8-dihydroxyflavone li ka thusa ho thibela mafu a neurodegenerative le ho fokotseha ha kelello ho amanang le lilemo.
4. Tšehetso ea Antioxidant: Molemo o mong o moholo oa li-supplement tsa 7,8-dihydroxyflavone ke thepa ea eona ea antioxidant. Li-antioxidants ke metsoako e thusang ho sireletsa 'mele hore o se ke oa senyeha, e leng limolek'hule tse kotsi tse ka tlatsetsang ho mefuta e sa tšoaneng ea mafu a sa foleng le botsofali. Ka ho senya li-radicals tsa mahala le ho fokotsa khatello ea oxidative, 7,8-DHF e ka thusa ho tšehetsa bophelo bo botle le bophelo bo botle ka kakaretso.
5.Tšusumetso e khahlanong le ho ruruha: Ho ruruha ke mokhoa oa tlhaho o thusang 'mele ho loantša tšoaetso le ho folisa tšenyo. Leha ho le joalo, ho ruruha ho sa foleng ho ka baka mathata a sa tšoaneng a bophelo bo botle, ho akarelletsa lefu la pelo, lefu la tsoekere le kankere. Li-supplement tsa 7,8-Dihydroxyflavone li bontšitsoe hore li na le liphello tse khahlanong le ho ruruha, tse thusang ho fokotsa kotsi ea ho ruruha ho sa foleng le likotsi tsa eona tsa bophelo bo botle.
E 'ngoe ea lintho tsa pele tseo u lokelang ho nahana ka tsona ha u khetha tlatsetso ea 7,8-dihydroxyflavone ke boleng ba metsoako. Batla lisebelisoa tse nang le 7,8-DHF e hloekileng, ea boleng bo holimo e se nang li-filler kapa metsoako ea maiketsetso. Ho bohlokoa hape ho nahana ka mohloli oa 7,8-DHF ea hau - sheba li-supplement tse lekotsoeng ho bona bohloeki le matla.
Ntle le boleng ba metsoako, ho bohlokoa hape ho nahana ka litekanyetso le mofuta oa tlatsetso. 7,8-Dihydroxyflavone e fumaneha ka mefuta ea capsule le phofo, 'me tekanyo e ka fapana pakeng tsa lihlahisoa. Ka kopo, nahana ka likhetho tsa hau le litlhoko tsa hau ha u khetha foromo le litekanyetso tse u loketseng. Ho ka 'na ha boela ha e-ba molemo ho buisana le setsebi sa tlhokomelo ea bophelo ho fumana hore na litekanyetso li lumellana hantle le litlhoko tsa hau ka bomong.
Ntho e 'ngoe ea bohlokoa eo u ka e nahanang ha u khetha tlatsetso ea 7,8-dihydroxyflavone ke botumo ba moetsi. Batla li-supplement tse entsoeng ke k'hamphani e tsebahalang e nang le nalane ea ho hlahisa lihlahisoa tsa boleng bo holimo, tse tšepahalang. Sheba litifikeiti tse joalo ka Mekhoa e Metle ea Tlhahiso (GMP) le tlhahlobo ea motho oa boraro ho netefatsa hore li-supplement tsa hau li fihlela maemo a holimo le polokeho.
Hape ke mohopolo o motle ho bala litlhahlobo le bopaki ho tsoa ho basebelisi ba bang ho fumana mohopolo oa katleho le boleng ba tlatsetso. Batla maikutlo a batho ba sebelisitseng sehlahisoa sena bakeng sa ts'ehetso ea kelello le bophelo bo botle ba boko ka kakaretso ho utloisisa hantle hore na tlatsetso ena e sebetsa joang ho uena.
Qetellong, nahana ka litšenyehelo le boleng ba li-supplement tsa hau. Leha ho le bohlokoa ho khetha lihlahisoa tsa boleng bo holimo, ho bohlokoa hape ho nahana ka litšenyehelo le boleng ba li-supplement tsa hau. Bapisa litheko 'me u nahane ka litšenyehelo tsa ho sebeletsa ho etsa bonnete ba hore u fumana chelete ea hau.
Litlhaloso tsa likarolo tsa Suzhou Myland Pharm & Nutrition Inc. esale e sebetsa khoebong ea tlatsetso ea phepo e nepahetseng ho tloha ka 1992. Ke k'hamphani ea pele naheng ea China ho hlahisa le ho etsa khoebo moqomo oa peo ea morara.
Ka boiphihlelo ba lilemo tse 30 'me e khannoa ke theknoloji e phahameng le leano le ntlafalitsoeng la R&D, k'hamphani e thehile lihlahisoa tse ngata tsa tlholisano mme ea fetoha tlatsetso e ncha ea mahlale a bophelo, ho kopanya tloaelo le khamphani ea lits'ebeletso tsa tlhahiso.
Ntle le moo, khamphani hape ke moetsi ea ngolisitsoeng ke FDA, e netefatsang bophelo bo botle ba batho ka boleng bo tsitsitseng le kholo e tsitsitseng. Lisebelisoa tsa k'hamphani tsa R&D le lisebelisoa tsa tlhahiso le lisebelisoa tsa tlhahlobo ke tsa sejoale-joale ebile li na le mesebetsi e mengata, 'me li khona ho hlahisa lik'hemik'hale ka sekala sa milligram ho isa ho tone ho latela litekanyetso tsa ISO 9001 le mekhoa ea tlhahiso ea GMP.
Q: 7,8-Dihydroxyflavone ke eng?
A: 7,8-Dihydroxyflavone ke flavonoid ea tlhaho e ithutoang bakeng sa melemo ea eona ea bophelo bo botle, ho kenyelletsa le phello ea eona mosebetsing oa kelello le bophelo bo botle ka kakaretso.
P: Li-supplement tsa 7,8-Dihydroxyflavone li sebetsa joang?
A: Li-supplement tsa 7,8-Dihydroxyflavone li lumeloa hore li sebetsa ka ho tšehetsa mosebetsi oa protheine ea bohlokoa bokong e bitsoang TrkB, e amehang khōlong le ho phela ha methapo ea kutlo. Tšehetso ena e ka thusa ho ntlafatsa ts'ebetso ea kelello le bophelo bo botle ba kelello.
P: Melemo e ka bang teng ea ho nka li-supplement tsa 7,8-Dihydroxyflavone ke life?
A: Melemo e meng e ka bang teng ea ho nka li-supplement tsa 7,8-Dihydroxyflavone e ka kenyelletsa mohopolo o ntlafalitsoeng le ts'ebetso ea kelello, ts'ehetso ea bophelo bo botle ba boko, le litlamorao tse ka eketsang maikutlo.
P: Li-supplement tsa 7,8-Dihydroxyflavone li lokela ho nkoa joang?
A: Tekanyo e nepahetseng ea li-supplement tsa 7,8-Dihydroxyflavone e ka fapana ho itšetlehile ka lintlha tsa motho ka mong, kahoo ho molemo ho latela litekanyetso tse khothalletsoang ho label ea sehlahisoa kapa ho buisana le setsebi sa tlhokomelo ea bophelo bakeng sa tataiso.
Boitlhotlhollo: Sengoloa sena ke sa tlhaiso-leseling e akaretsang feela 'me ha ea lokela ho nkuoa e le keletso efe kapa efe ea bongaka. Tse ling tsa litaba tsa poso ea blog li tsoa Marang-rang mme ha se setsebi. Sebaka sena sa marang-rang se na le boikarabello ba ho hlophisa, ho hlophisa le ho hlophisa lingoliloeng. Sepheo sa ho fetisa boitsebiso bo bongata ha se bolele hore u lumellana le maikutlo a eona kapa u tiisa bonnete ba litaba tsa eona. Kamehla buisana le setsebi sa tlhokomelo ea bophelo pele u sebelisa li-supplement leha e le life kapa u etsa liphetoho tsamaisong ea tlhokomelo ea bophelo.
Nako ea poso: Feb-20-2024
