Ho notlolla Liphiri tsa Spermidine: Lisebelisoa tse sebetsang ho phela nako e telele le bophelo bo botle

Lilemong tsa morao tjena, sechaba sa mahlale se tsepamisitse maikutlo haholo karolong ea autophagy ho khothaletsa bophelo bo botle le bophelo bo bolelele. Autophagy, mokhoa oa cellular o tlosang likarolo tse senyehileng le ho tsosolosa lisebelisoa tsa cellular, ke tsa bohlokoa bakeng sa ho boloka homeostasis ea cellular le mosebetsi. Motsoako o mong o hapileng tlhokomelo bakeng sa bokhoni ba ona ba ho ntlafatsa autophagy ke spermidine, polyamine ea tlhaho e fumanehang lijong tse fapaneng. Sehlooho sena se hlahloba melemo ea spermidine, mehloli ea eona ea lijo tse molemo ka ho fetisisa, le karolo ea eona e tšepisang ho thibela botsofali.

Spermidine ke eng?

Spermidine ke polyamine e bapalang karolo ea bohlokoa lits'ebetsong tsa lisele, ho kenyelletsa kholo ea lisele, ho ata le ho arola. E entsoe 'meleng ho tloha ho amino acid ornithine' me e ameha mesebetsing e fapaneng ea likokoana-hloko, tse kang ho tsitsisa DNA, gene expression, le pontšo ea lisele. Le hoja 'mele ea rona e hlahisa spermidine, ho ja lijo ho ka ama maemo a eona haholo.

Melemo eaSpermidine

Lipatlisiso li bontšitse hore spermidine e fana ka melemo e mengata ea bophelo bo botle, haholo-holo tabeng ea ho tsofala le ho phela nako e telele. Mona ke e meng ea melemo e tsebahalang haholo:

1. E khothalletsa Autophagy: Spermidine e 'nile ea bontšoa hore e etsa hore motho a se ke a hlola a e-ba teng, e leng mokhoa o thusang ho hlakola lisele le liprotheine tse senyehileng. Ka ho khothalletsa autophagy, spermidine e ka thusa ho sireletsa khahlanong le maloetse a amanang le lilemo le ho ntlafatsa bophelo bo botle ba lisele.

2. Bophelo bo botle ba pelo: Liphuputso li bontša hore spermidine e ka ba le liphello tsa pelo. E 'nile ea amahanngoa le ts'ebetso e ntlafetseng ea pelo, ho fokotsa khatello ea mali, le ho fokotsa kotsi ea mafu a pelo. Motsoako o ka thusa ho boloka elasticity ea methapo ea mali le ho fokotsa ho ruruha, ho kenya letsoho bophelong bo botle ba pelo.

3. Neuroprotection: Spermidine e bontšitse lisebelisoa tsa neuroprotective, tse ka thusang ho thibela mafu a neurodegenerative a kang Alzheimer's le Parkinson. Ka ho khothaletsa autophagy, spermidine e ka thusa ho hlakola liprotheine tse chefo tse bokellanang bokong, ka hona li ts'ehetsa ts'ebetso ea kelello le mohopolo.

4. Liphello Tse Khahlanong le Ho ruruha: Ho ruruha ho sa foleng ke letšoao la mafu a mangata a amanang le lilemo. Spermidine e bontšitsoe hore e na le liphello tse khahlanong le ho ruruha, tse ka fokotsang kotsi ea maemo a kang ramatiki, lefu la tsoekere le mefuta e meng ea kankere.

5. Bophelo bo Botle ba Metabolic: Lipatlisiso li bontša hore spermidine e ka phetha karolo ea ho laola metabolism le ho khothalletsa ho laola boima ba 'mele. E amahanngoa le ntlafatso ea kutloisiso ea insulin le metabolism ea tsoekere, tse bohlokoa bakeng sa ho thibela mathata a metabolism.

Spermidine le Anti-botsofali

Ho batla litharollo tse thibelang botsofali ho entse hore ho be le thahasello ho spermidine. Ha re ntse re tsofala, katleho ea autophagy e fokotseha, e lebisang ho bokelleng likarolo tse senyehileng tsa cellular. Ka ho matlafatsa autophagy, spermidine e ka thusa ho loantša tse ling tsa liphello tsa botsofali.

Liphuputso tse 'maloa li bontšitse hore tlatsetso ea spermidine e ka lelefatsa bophelo ba lintho tse fapaneng, ho kenyelletsa le tomoso, liboko le lintsintsi. Le hoja liphuputso tsa batho li sa ntsane li le bonyenyaneng, liphuputso tsa pele lia tšepisa. Bafuputsi ba lumela hore spermidine e ka thusa ho ntlafatsa bophelo bo botle-nako ea bophelo bo sebelisitsoeng ka bophelo bo botle-ka ho lieha ho qala ha mafu a amanang le lilemo.

Mehloli e Molemo ka ho Fetisisa ea Spermidine

Le hoja spermidine e fumaneha e le tlatsetso ea lijo, e ka boela ea fumanoa ka lijo tse fapa-fapaneng. Ho kenyelletsa lijo tse nang le spermidine lijong tsa hau ke mokhoa oa tlhaho oa ho matlafatsa maemo a hau a motsoako ona o molemo. Mona ke tse ling tsa mehloli e molemo ka ho fetisisa ea spermidine:

1. Lijo Tse Betseng: Lihlahisoa tse lomositsoeng tse kang natto (linaoa tse lomositsoeng tsa soya), miso, le sauerkraut ke mehloli e babatsehang ea spermidine. Ts'ebetso ea ho belisoa e ntlafatsa bioavailability ea spermidine, e nolofalletsa 'mele ho monya.

2. Lijo-thollo: Lithollo tse felletseng tse kang kokoana-hloko ea koro, oats, le raese e sootho li na le spermidine e ngata. Ho kenyelletsa lijo-thollo tsena lijong tsa hau ho ka fana ka mohloli o phetseng hantle oa lik'habohaedreite hammoho le melemo ea spermidine.

3. Li-legumes: Linaoa, lensisi le lierekisi hase feela hore li na le liprotheine tse ngata le fiber empa hape li na le tekanyo e khōlō ea spermidine. Ke lisebelisoa tse fapaneng tse ka ekeletsoang lijana tse fapaneng.

4. Meroho: Meroho e meng, haholo-holo ea lelapa la cruciferous, e kang broccoli, cauliflower le limela tsa Brussels, ke mehloli e molemo ea spermidine. Meroho e makhasi a kang spinach le khale le eona e kenya letsoho ho jeoang ke spermidine.

5. Litholoana: Litholoana tse ling, ho kopanyelletsa le lilamunu, liapole le li-avocado, li na le spermidine, le hoja e le tse nyenyane ha li bapisoa le mehloli e meng ea lijo. Ho kenyelletsa litholoana tse fapa-fapaneng lijong tsa hau ho ka u thusa ho fumana phepo e nepahetseng ea limatlafatsi.

6. Li-mushroom: Mefuta e meng ea li-mushroom, tse kang shiitake le maitake, li tsejoa hore li na le spermidine. E ka ba tlatsetso e monate ea lijo ha e ntse e fana ka melemo ea bophelo bo botle.

Myland Nutraceuticals Inc. ke moetsi ea ngolisitsoeng oa FDA ea fanang ka boleng bo phahameng, bohloeki bo phahameng ba Spermidine phofo.

Ho Myland Nutraceuticals Inc., re ikemiselitse ho fana ka lihlahisoa tsa boleng bo holimo ka litheko tse ntle. Phofo ea rona ea Spermidine e etsa liteko tse matla bakeng sa bohloeki le potency, ho netefatsa hore o fumana tlatsetso ea boleng eo u ka e tšepang. Hore na o batla ho ts'ehetsa bophelo bo botle ba lisele, ho matlafatsa sesole sa hau sa 'mele, kapa ho ntlafatsa boiketlo ba hau ka kakaretso, phofo ea rona ea Spermidine ke khetho e phethahetseng bakeng sa hau. 

Ka phihlelo ea lilemo tse 30 'me e khannoa ke thekenoloji e phahameng le maano a R&D a ntlafalitsoeng haholo, Myland Nutraceuticals Inc. e hlahisitse lihlahisoa tse ngata tsa tlholisano e le tlatsetso e ncha ea mahlale a bophelo, tlhahiso ea moetlo le k'hamphani ea lits'ebeletso tsa tlhahiso.

Ho feta moo, Myland Nutraceuticals Inc. hape ke moetsi ea ngolisitsoeng oa FDA. Lisebelisoa tsa k'hamphani tsa R&D, lisebelisoa tsa tlhahiso, le lisebelisoa tsa tlhahlobo ke tsa sejoale-joale ebile li sebetsa ka mefuta-futa, 'me li khona ho hlahisa lik'hemik'hale ka milligram ho isa ho tone le ho latela litekanyetso tsa ISO 9001 le litlhaloso tsa tlhahiso GMP.

Qetello

Spermidine e hlaha e le molekane ea matla molemong oa bophelo bo botle le bophelo bo bolelele. Bokhoni ba eona ba ho khothaletsa autophagy, ho ts'ehetsa bophelo bo botle ba pelo, le ho fana ka litlamorao tsa neuroprotective ho etsa hore e be motsoako o lokelang ho nahanoa maemong a botsofali. Ka ho kenyelletsa lijo tse nang le spermidine lijong tsa hau, ka tlhaho u ka eketsa maemo a hau a polyamine ena e molemo mme o ka ntlafatsa bophelo bo botle ba hau ka kakaretso.

 

Ha lipatlisiso li ntse li tsoela pele, bokamoso bo shebahala bo tšepisa spermidine e le mokhoa oa tlhaho oa ho khothalletsa bophelo bo bolelele le ho loantša maloetse a amanang le lilemo. Ebang ke ka mehloli ea lijo kapa tlatsetso, spermidine e ka ba le senotlolo sa ho bula bophelo bo botle le bo bolelele.