Nicotinamide riboside chloride powder, eo hape e tsejoang e le NRC, ke mofuta oa vithamine B3 e tsebahalang sechabeng sa bophelo bo botle le bophelo bo botle bakeng sa melemo ea eona e ka bang teng. Motsoako ona ke selelekela sa nicotinamide adenine dinucleotide (NAD+), coenzyme e bapalang karolo ea bohlokoa lits'ebetsong tse fapaneng tsa tlhaho, ho kenyeletsoa Energy metabolism le tokiso ea DNA. Nicotinamide Riboside Chloride Powder e na le monyetla oa ho ba tlatsetso ho ts'ehetsa tlhahiso ea matla a cellular, ho khothaletsa litlamorao tse khahlanong le botsofali, le ho thusa bophelo bo botle ba pelo.
NAD (Nicotinamide Adenine Dinucleotide) ke coenzyme e fumanoang liseleng tsohle tse phelang 'me e bohlokoa bakeng sa mekhoa e fapaneng ea likokoana-hloko' meleng. E phetha karolo ea bohlokoa tlhahisong ea matla, tokiso ea DNA, le pontšo ea lisele, e leng se etsang hore e be karolo ea bohlokoa ea bophelo bo botle le bophelo bo botle.
NAD e kenya letsoho tlhahisong ea matla a cellular. Ke karolo ea bohlokoa tšebetsong ea ho fetola limatlafatsi tse kang lik'habohaedreite, mafura le liprotheine hore e be adenosine triphosphate (ATP), molek'hule eo e leng mohloli oa matla oa sele. NAD ke karolo ea bohlokoa ea ketane ea lipalangoang tsa elektronike, letoto la karabelo e etsahalang mitochondria, matla a lisele, ho hlahisa ATP. Ntle le phepelo e lekaneng ea NAD, matla a 'mele a ho hlahisa matla a senyeha, e leng se lebisang mokhathala le ho fokotsa ts'ebetso ea' mele le kelello.
Ntle le karolo ea eona ho metabolism ea matla, NAD e boetse e bapala karolo ea bohlokoa tokisong ea DNA. Hobane lisele li lula li pepesehetse khatello ea tikoloho le lintho tse ka hare tse ka bakang tšenyo ea DNA, 'mele o itšetlehile ka li-enzyme tse itšetlehileng ka NAD (tse bitsoang Sirtuins) ho lokisa le ho boloka botšepehi ba liphatsa tsa lefutso. Li-Sirtuin li ameha mekhoeng e fapaneng ea lisele, ho kenyelletsa tokiso ea DNA, polelo ea liphatsa tsa lefutso, le taolo ea metabolism. Ka ho ts'ehetsa ts'ebetso ea li-sirtuin, NAD e thusa ho boloka botsitso ba liphatsa tsa lefutso le ho fokotsa kotsi ea liphetoho tse ka lebisang mafung a kang mofetše.
Ho feta moo, NAD ke sebapali sa bohlokoa litseleng tsa lipontšo tsa lisele tse laolang mesebetsi e fapaneng ea 'mele, ho kenyelletsa metabolism, morethetho oa circadian, le likarabo tsa khatello ea maikutlo. E sebetsa e le coenzyme bakeng sa li-enzyme tse amehang litseleng tsena tsa matšoao, e li lumellang ho etsa mesebetsi ea tsona hantle. Ka mohlala, enzyme e itšetlehileng ka NAD e bitsoang PARP (poly-ADP-ribose polymerase) e ameha taolong ea tokiso ea DNA le mekhoa ea ho arabela khatello ea kelello ea lisele. Ka ho tšehetsa mosebetsi oa PARP, NAD e thusa ho boloka bophelo bo botle le ho tiea ha lisele ha ho tobane le mathata.
Maemo a NAD 'meleng a ka angoa ke lintlha tse fapaneng, ho kenyelletsa lilemo, lijo le mokhoa oa bophelo. Ha batho ba ntse ba tsofala, maemo a NAD a atisa ho fokotseha, e leng se ka bang le liphello bakeng sa bophelo bo botle ka kakaretso le mekhoa e amanang le botsofali. Ho feta moo, lintlha tse ling tsa lijo, tse kang khaello ea niacin (vithamine B3), li ka tlatsetsa khaellong ea NAD, athe mekhoa ea bophelo, joalo ka ho noa joala ho feta tekano, e ka fokotseha.Boemo ba NAD.
Nicotinamide riboside chloride (NRC ka bokhutšoanyane)ke ntho e nkiloeng ho vithamine B3 le mofuta o mocha oa bioactive ntho. E entsoe ka molek'hule ea tsoekere ea ribose le karolo ea vithamine B3 nicotinamide (eo hape e tsejoang e le nicotinic acid kapa vithamine B3). E ka jeoa ka ho ja nama, tlhapi, lijo-thollo le lijo tse ling kapa ka li-supplement tsa NRC.
Nicotinamide ribose chloride e ka fetoloa NAD+ (nicotinamide adenine dinucleotide) 'me ea sebetsa ka har'a lisele. NAD + ke coenzyme ea bohlokoa ea intracellular e kenyang letsoho mekhoeng e sa tšoaneng ea lik'hemik'hale tsa lisele, ho kenyelletsa tlhahiso ea matla, ho lokisoa ha DNA, ho ata ha lisele, joalo-joalo Nakong ea botsofali ba 'mele oa motho, litaba tsa NAD + li fokotseha butle-butle. Nicotinamide riboside chloride supplementation e ka eketsa boemo ba NAD +, e lebelletsoeng ho liehisa ho hlaha ha botsofali ba lisele le mafu a amanang.
Patlisiso ka nicotinamide riboside chloride e bonts'itse hore e na le mesebetsi e mengata ea tlhaho, joalo ka:
Ntlafatsa metabolism ea matla, eketsa mamello le ts'ebetso ea boikoetliso;
Ntlafatsa ts'ebetso ea methapo le mohopolo;
Ntlafatsa ts'ebetso ea sesole sa 'mele.
Ka kakaretso, nicotinamide riboside chloride ke motsoako o ts'episang haholo oa phepo o nang le tebello e pharalletseng ea ts'ebeliso.
Ntle le moo, nicotinamide ribose chloride e boetse e sebelisoa haholo lipatlisisong tsa mahlale. E le ntho ea pele ea NAD+, e ka sebelisoa ho ithuta biosynthesis le litsela tsa metabolic tsa NAD+ le litaba tse ling tse amanang le tsona. Ka nako e ts'oanang, nicotinamide riboside chloride e boetse e sebelisoa e le motsoako oa lihlahisoa tsa bophelo bo botle le litlolo ho khothaletsa bophelo bo botle ba lisele le ho fokotsa botsofali ba letlalo.
Nicotinamide riboside chloride ke mofuta oa kristale oa nicotinamide riboside (NR) chloride eo ka kakaretso e nkoang e bolokehile hore e ka sebelisoa lijong le litlatsetsong tsa lijo. Nicotinamide riboside ke mohloli oa vithamine B3 (nicotinic acid), e ka ntlafatsang metabolism ea oxidative le ho thibela ho se tloaelehe ha metabolism ho bakoang ke lijo tse mafura a mangata. Nicotinamide riboside ke vithamine ea NAD (NAD +) e sa tsoa sibolloa.
Nicotinamide ribosideke mofuta oa vithamine B3 e ithutoang bakeng sa karolo ea eona e ka bang teng ho ts'ehetsa tlhahiso ea matla a cellular le bophelo bo botle ba metabolism. Ke selelekela sa nicotinamide adenine dinucleotide (NAD+), coenzyme e bapalang karolo ea bohlokoa lits'ebetsong tse fapaneng tsa cellular, ho kenyelletsa metabolism ea matla le tokiso ea DNA. le polelo ea liphatsa tsa lefutso.
Nicotinamide riboside chloride, ka lehlakoreng le leng, ke mofuta oa letsoai oa nicotinamide riboside mme o sebelisoa hangata ho li-supplement tsa lijo. Sepheo sa ho eketsa chloride ho nicotinamide riboside ke ho matlafatsa botsitso le bioavailability ea eona, ho nolofalletsa 'mele ho monya le ho o sebelisa. Mofuta ona oa NR o ile oa ntlafatsoa ho sebetsana le tse ling tsa mefokolo ea nicotinamide riboside e tloaelehileng, joalo ka ho se tsitse ha eona ho ka bang teng tlasa maemo a itseng le bioavailability e tlase.
Phapang e 'ngoe ea mantlha lipakeng tsa nicotinamide riboside le nicotinamide riboside chloride ke sebopeho sa tsona sa lik'hemik'hale. Nicotinamide riboside ke molek'hule e bonolo e entsoeng ka setsi sa nicotinamide le ribose, ha nicotinamide riboside chloride e le molek'hule e tšoanang le li-ion tsa chloride. Phapang ena ea sebopeho e ama tsela eo 'mele o sebetsang le ho sebelisa metsoako ena, e ka amang katleho ea eona le bioavailability.
Mabapi le melemo ea bona ea bophelo bo botle, nicotinamide riboside le nicotinamide riboside chloride ho nahanoa hore li tšehetsa maemo a NAD+ 'meleng, e leng se bakang litlamorao tse atileng tšebetsong ea lisele le bophelo bo botle ka kakaretso. NAD+ e bohlokoa bakeng sa ts'ebetso e nepahetseng ea li-sirtuin, li-enzyme tse bapalang karolo ea bohlokoa ho laola metabolism ea lisele, tokiso ea DNA, le karabelo ea 'mele khatellong ea maikutlo. Ka ho ts'ehetsa maemo a NAD +, mefuta e 'meli ea NR e ka thusa ho khothaletsa botsofali bo botle, ho ntlafatsa ts'ebetso ea mitochondrial, le ho eketsa matla a liselefouno.
Leha ho le joalo, tlatsetso ea chloride ho nicotinamide riboside e ka fana ka melemo e itseng mabapi le botsitso le bioavailability. Ho ba teng ha chloride ho thusa ho sireletsa molek'hule ho senyeha, ho etsa bonnete ba hore e lula e tiile ebile e sebetsa ha e sebelisoa e le tlatsetso. Ntle le moo, li-ion tsa chloride li ka ntlafatsa ho qhibiliha ha nicotinamide riboside, ho nolofalletsa 'mele ho monya le ho o sebelisa.
Nicotinamide riboside e kentse letsoho ho eketseheng ha methapo ea NAD le ho susumetsa kutloisiso ea insulin hammoho le ho ntlafatsa ts'ebetso ea sirtuin. Bokhoni ba eona ba ho eketsa tlhahiso ea NAD bo fana ka maikutlo a hore nicotinamide riboside e ka boela ea ntlafatsa bophelo bo botle ba mitochondrial, ea susumetsa ts'ebetso ea mitochondrial le ho susumetsa tlhahiso ea mitochondria e ncha. Lithuto tse ling tse sebelisang nicotinamide riboside mefuteng ea lefu la Alzheimer's li bonts'itse hore molek'hule e fumaneha bokong 'me e ka fana ka tšireletso ea methapo ka ho susumetsa boko ba NAD synthesis.
1. Metabolism ea matla: E 'ngoe ea litšebeliso tsa mantlha tsa nicotinamide riboside chloride ke karolo ea eona ho metabolism ea matla. NAD+ e bohlokoa bakeng sa tlhahiso ea adenosine triphosphate (ATP), chelete ea mantlha ea matla ea sele. Ka ho ts'ehetsa maemo a NAD +, Nicotinamide Riboside Chloride e ka thusa ho ntlafatsa tlhahiso ea matla a cellular, ka hona ea matlafatsa matla le bophelo bo botle ka kakaretso.
2. Botsofali bo Botle: Joalokaha ho boletsoe pejana, maemo a NAD + a fokotseha ka lilemo, 'me ho fokotseha hona ho amahanngoa le mefuta e sa tšoaneng ea mathata a bophelo bo amanang le lilemo, ho kenyelletsa le ho fokotseha ha kelello, ho se sebetse ha metabolism, le ho fokotsa ts'ebetso ea lisele. Nicotinamide Riboside Chloride ho nahanoa hore e ts'ehetsa maemo a NAD +, e ka khothaletsang botsofali bo botle le ho fokotsa mathata a bophelo bo amanang le botsofali.
3. Tokiso ea DNA: NAD + e ameha ts'ebetsong ea ho lokisa DNA, e leng ea bohlokoa bakeng sa ho boloka botsitso ba genome le ho thibela ho bokellana ha tšenyo ea DNA. Ka ho ts'ehetsa maemo a NAD+, nicotinamide riboside chloride e ka thusa ho ntlafatsa mekhoa ea tokiso ea DNA, e ka fokotsang kotsi ea mafu a amanang le botsofali le ho khothaletsa bophelo bo botle ba liselefouno.
4. Bophelo bo Botle ba Metabolic: Nicotinamide riboside chloride e ithutoe bakeng sa karolo ea eona e ka bang teng ho ts'ehetsa bophelo bo botle ba metabolism. Lipatlisiso li fana ka maikutlo a hore e ka thusa ho ntlafatsa kutloisiso ea insulin, ho laola maemo a tsoekere ea mali le ho ts'ehetsa metabolism e phetseng hantle ea lipid, ho e etsa sesebelisoa se ka bang teng taolong ea mafu a metabolism a kang lefu la tsoekere le botenya.
Melemo ea Nicotinamide Riboside Chloride
1. E Ntlafatsa Mosebetsi oa Lisele: Ka ho tšehetsa maemo a NAD+, nicotinamide riboside chloride e ka thusa ho ntlafatsa tšebetso ea lisele, kahoo ea ntlafatsa bophelo bo botle le matla ka kakaretso.
2. Tšehetso ea Kelello: Liphuputso tse ling li bontša hore nicotinamide riboside chloride e ka tšehetsa ts'ebetso ea kelello le bophelo bo botle ba boko, e leng se etsang hore e be sesebelisoa se ka khonehang sa ho khothalletsa ho hlaka kelellong le ho sebetsa hantle.
3. Bophelo bo Botle ba Mitochondrial: NAD + e phetha karolo ea bohlokoa mosebetsing oa mitochondrial, matla a matla a sele. Ka ho ts'ehetsa maemo a NAD+, nicotinamide riboside chloride e ka thusa ho ntlafatsa bophelo bo botle ba mitochondrial, kahoo ea eketsa tlhahiso ea matla le ts'ebetso ea liselefouno ka kakaretso.
4. Ts'ebetso ea Liatleletiki: Liphuputso tse ling li fana ka maikutlo a hore nicotinamide riboside chloride e ka tšehetsa ts'ebetso ea lipapali le ho hlaphoheloa ka ho matlafatsa tlhahiso ea matla a cellular le ho fokotsa khatello ea oxidative.
5.Letlalo la Bophelo bo Botle: NAD + e ameha mekhoeng e sa tšoaneng ea bophelo bo botle ba letlalo, ho kenyeletsa ho lokisoa ha DNA le ho tsosolosoa ha lisele. Niacinamide riboside chloride e ka thusa ho ts'ehetsa lits'ebetso tsena, e leng monyetla oa ho khothaletsa letlalo le phetseng hantle le le lecha.
Na u nahana ho eketsa phofo ea nicotinamide riboside chloride (NRC) ho tlatsetso ea hau ea letsatsi le letsatsi? Leha ho le joalo, ha se li-powders tsohle tsa NRC tse tšoanang 'me ke habohlokoa ho tseba seo u lokelang ho se sheba ha u reka. teng
Bohloeki le Boleng
Bohloeki le boleng e lokela ho ba lintlha tsa hau tse ka sehloohong ha u reka phofo ea NRC. Batla lihlahisoa tse lekiloeng ke motho oa boraro bakeng sa bohloeki le matla. Sena se tiisa hore phofo ha e na litšila 'me e na le palo e behiloeng ea nicotinamide riboside chloride. Ho feta moo, nahana ka ho khetha li-powders tse hlahisoang lifekthering tse latelang Mekhoa e Metle ea Tlhahiso (GMP) ho netefatsa boleng le polokeho.
Bioavailability
The bioavailability ea phofo ea NRC, kapa bokhoni ba 'mele ba ho monya le ho sebelisa motsoako, ke ntlha ea bohlokoa e lokelang ho nahanoa. Batla phofo e entsoeng ka ho khetheha ho matlafatsa bioavailability, joalo ka e nang le metsoako e tšehetsang ho monya, joalo ka piperine kapa resveratrol. Bioavailability e ntlafetseng e thusa ho netefatsa hore 'mele oa hau o ka sebelisa nicotinamide riboside chloride hantle ho eketsa melemo ea eona.
Tekanyo le boholo ba ho sebeletsa
Ka kopo, nahana ka tekanyo le boholo ba tšebeletso ha u khetha phofo ea NRC. Li-powders tse ling li ka hloka boholo bo boholo ba ho sebeletsa ho fihlela tekanyo e lakatsehang ea nicotinamide riboside, ha li-powders tse ling li ka fana ka mofuta o tsitsitseng haholoanyane. Ela hloko litekanyetso tse khothaletsoang le boholo ba litšebeletso ho netefatsa hore li fihlela litlhoko tsa hau le likhetho tsa hau.
Recipe le lisebelisoa tse eketsehileng
Ntle le nicotinamide riboside chloride, phofo e 'ngoe ea NRC e kanna ea ba le lisebelisoa tse ling ho ts'ehetsa bophelo bo botle ka kakaretso. Ka mohlala, lihlahisoa tse ling li ka ba le li-antioxidants kapa metsoako e meng e tlatsetsang liphello tsa NRC. Nahana hore na u khetha phofo e bonolo, e hloekileng ea NR, kapa e nang le lisebelisoa tse eketsehileng ho fana ka mokhoa o pharaletseng haholoanyane oa bophelo bo botle ba cellular.
Botumo ba Brand le Ponaletso
Ha u reka tlatsetso efe kapa efe, ho bohlokoa ho nahana ka botumo ba lebitso le pepeneneng. Batla k'hamphani e nang le rekoto e netefalitsoeng ea ho hlahisa li-supplement tsa boleng bo holimo le ho fana ka leseli la sehlahisoa se pepeneneng. Sena se ka kenyelletsa lintlha tse mabapi le ho fumana, lits'ebetso tsa tlhahiso le tlhahlobo ea motho oa boraro. Ho khetha lebitso le tsebahalang le le pepeneneng ho ka u fa khotso ea kelello le kholiseho ho sehlahisoa seo u se rekang.
Maikutlo a bareki le maikutlo
Pele o reka, ka kopo iphe nako ea ho bala maikutlo a bareki le maikutlo mabapi le phofo ea NRC eo u e nahanang. Tsepamisa maikutlo ho boiphihlelo bo amanang le boleng ba sehlahisoa, katleho, le khotsofalo ka kakaretso. Leha liphihlelo tsa motho ka mong li ka fapana, maikutlo a bareki a ka fana ka leseli la bohlokoa mabapi le ts'ebetso ea sehlahisoa le ho u thusa ho etsa qeto u na le tsebo.
Theko khahlano le boleng
Qetellong, nahana ka theko le boleng ba phofo ea NRC. Leha ho le bohlokoa ho beha boleng pele, ho bohlokoa hape ho bapisa litheko le ho nahana ka boleng ba sehlahisoa ka kakaretso. Hopola hore lihlahisoa tsa theko e phahameng li ka fana ka boleng bo holimo kapa melemo ea tlatsetso, empa ho bohlokoa ho fumana tekano lipakeng tsa boleng le theko e lumellanang le tekanyetso ea hau le lintho tse tlang pele.
Suzhou Myland Pharm & Nutrition Inc. ke moetsi ea ngolisitsoeng ke FDA ea fanang ka phofo ea boleng bo phahameng le bo hloekileng ba Nicotinamide Riboside Chloride (NRC).
Ho Suzhou Myland Pharm re ikemiselitse ho fana ka lihlahisoa tsa boleng bo holimo ka litheko tse ntle. Phofo ea rona ea Nicotinamide Riboside Chloride (NRC) e lekoa ka thata bakeng sa bohloeki le potency, ho netefatsa hore o fumana tlatsetso ea boleng bo holimo eo u ka e tšepang. Ho sa tsotellehe hore na u batla ho tšehetsa bophelo bo botle ba lisele, ho matlafatsa sesole sa hau sa 'mele kapa ho ntlafatsa bophelo bo botle ka kakaretso, phofo ea rona ea Nicotinamide Riboside Chloride (NRC) ke khetho e phethahetseng.
P: Nicotinamide Riboside Chloride Powder ke eng?
A:Nicotinamide riboside chloride (NRC) ke mofuta oa vithamine B3 o fumaneng botumo bakeng sa melemo ea eona ea bophelo bo botle, haholo-holo ho ts'ehetsa tlhahiso ea matla a cellular le metabolism. Hangata NRC e rekisoa ka foromo ea phofo, e etsa hore e be bonolo ho ba ratang ho etsa litekanyetso tsa bona.
Q; Melemo ea Nicotinamide Riboside Chloride Powder ke Efe?
A: NRC e ithutoe ka bokhoni ba eona ba ho ts'ehetsa botsofali bo botle, ho ntlafatsa ts'ebetso ea mitochondrial, le ho matlafatsa mamello le ts'ebetso. E boetse e lumeloa hore e khothalletsa bophelo bo botle ba pelo le ts'ebetso ea kelello. Basebelisi ba bangata ba tlaleha ho eketseha ha maemo a matla le boiketlo ka kakaretso ka mor'a ho kenyelletsa NRC mekhoeng ea bona ea letsatsi le letsatsi.
Q; Nka Khetha Phofo ea boleng bo holimo ea Nicotinamide Riboside Chloride?
A: Ha u reka phofo ea NRC, ho bohlokoa ho etelletsa boleng le bohloeki pele. Batla morekisi ea nang le botumo bo botle ea fanang ka tlhahlobo ea mokha oa boraro ho netefatsa hore sehlahisoa ha se na litšila ebile se kopana le litekanyetso tsa matla. Ho feta moo, nahana ka lintlha tse kang ho fumana, lits'ebetso tsa tlhahiso, le maikutlo a bareki ho lekanya boleng ba sehlahisoa.
P: Nka Reka Hokae Nicotinamide Riboside Chloride Powder?
A: Phofo ea NRC e fumaneha habonolo ho tsoa ho barekisi ba fapaneng ba marang-rang, mabenkeleng a lijo tsa bophelo bo botle, le mabenkele a tlatselletsang a khethehileng. Ha u reka NRC, etelletsa pele barekisi ba tšepahalang ba fanang ka leseli le pepeneneng ka lihlahisoa tsa bona, ho kenyeletsoa ho fumana, liteko, le tšehetso ea bareki.
Boitlhotlhollo: Sengoloa sena ke sa tlhaiso-leseling e akaretsang feela 'me ha ea lokela ho nkuoa e le keletso efe kapa efe ea bongaka. Tse ling tsa litaba tsa poso ea blog li tsoa Marang-rang mme ha se setsebi. Sebaka sena sa marang-rang se na le boikarabello ba ho hlophisa, ho hlophisa le ho hlophisa lingoliloeng. Sepheo sa ho fetisa boitsebiso bo bongata ha se bolele hore u lumellana le maikutlo a eona kapa u tiisa bonnete ba litaba tsa eona. Kamehla buisana le setsebi sa tlhokomelo ea bophelo pele u sebelisa li-supplement leha e le life kapa u etsa liphetoho tsamaisong ea tlhokomelo ea bophelo.
Nako ea poso: Sep-13-2024
