Nefiracetam moetsi oa phofo CAS No.: 77191-36-7 99% bohloeki min. bakeng sa lisebelisoa tsa tlatsetso
Video ea Sehlahisoa
Lihlahisoa tsa lihlahisoa
| Lebitso la sehlahisoa | Nefiracetam |
| Lebitso le leng | n-(2,6-dimethylphenyl) -2-oxo-1-pyrrolidineacetamide;NEFIRACETAM; 2-oxo-1-pyrrolidinylaceticacid, 2,6-dimethylanilide; dm9384; n-(2,6-dimethylphenyl) -2-oxo-1-pyrrolidineacetamid;DM-9384,(2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide); DMMPA |
| Nomoro ea CAS. | 77191-36-7 |
| Mokhoa oa limolek'hule | C14H18N2O2 |
| Boima ba molek'hule | 246.3 |
| Bohloeki | 99.0% |
| Ponahalo | Phofo e tšoeu |
| Ho paka | 25kg/barrel |
| Kopo | nootropic |
Kenyelletso ea sehlahisoa
Nefiracetam ke ea lelapa la piracetam, sehlopha sa lithethefatsi tse tsejoang ka thepa ea tsona ea ho ntlafatsa tsebo. Nefiracetam e ile ea qaptjoa ka lekhetlo la pele lilemong tsa pele tsa 1980 'me ka potlako e ile ea khahla tlhokomelo ka lebaka la mokhoa o ikhethang oa ts'ebetso le mekhoa ea phekolo e ka' nang ea e-ba teng. Motsoako ona oa morabe ho nahanoa hore o ama li-neurotransmitters le li-receptor bokong, qetellong o khothaletsa bokhoni bo ntlafetseng ba kelello. Nefiracetam e ama haholo-holo maemo a boko ba acetylcholine, neurotransmitter ea bohlokoa e ikarabellang bakeng sa mohopolo, ho ithuta le ts'ebetso ea kelello. Ka ho fetola li-receptor tsa acetylcholine, nefiracetam e khothalletsa puisano e eketsehileng pakeng tsa li-neurone, kahoo e ntlafatsa polasetiki ea synaptic le ho ntlafatsa ho boloka mohopolo. Ho phaella moo, nefiracetam e sebelisana le li-receptor tsa gamma-aminobutyric acid (GABA) ho thusa ho leka-lekanya boemo ba li-neurotransmitter. Ka ho ama li-neurotransmitters tse hlasimollang le tse thibelang, nefiracetam e thusa ho boloka ts'ebetso e nepahetseng ea boko, kahoo e ntlafatsa ho tsepamisa maikutlo, tlhokomelo le ts'ebetso ea kelello ka kakaretso.
Sebopeho
(1) Bohloeki bo phahameng: Nefiracetam e ka fumana lihlahisoa tse hloekileng ka ho hloekisa mekhoa ea tlhahiso. Bohloeki bo phahameng bo bolela bioavailability e betere le ho fokotseha ho hoholo ha maikutlo.
(2) Tšireletseho: Tšireletseho e phahameng, liketso tse seng kae tse mpe.
(3) Botsitso: Nefiracetam e na le botsitso bo botle 'me e ka boloka ts'ebetso ea eona le phello tlas'a maemo a fapaneng le maemo a polokelo.
Lisebelisoa
Nefiracetam ke hydrophobic derivative ea piracetam, eo ka kakaretso e nkoang e le ntho e ikarabellang bakeng sa ho sibolloa ha liteishene tsa calcium 'meleng le ho fetisoa ka tsela e sa tobang ea lintho tse bontšang thabo e le karolo ea agonist ea li-channel tsa calcium ion. Sebaka se tlamang sa Glycine sa NDMA receptor. Ka phello ea eona ho cerebral cortex, nefiracetam e ka ntlafatsa bokhoni ba kelello le ho thibela ho senyeha ha thuto le mohopolo. Ha e na thepa ea muscarinic receptor agonist kapa antagonist, ebile ha e thibele ts'ebetso ea acetylcholinease. Ka hona, liphello tsa eona tse khahlanong le amnestic le ho ntlafatsa mohopolo li finyelloa ka ho ntlafatsa ho lokolloa ha acetylcholine ka har'a cerebral cortex.
