Moetsi oa phofo ea Amino Tadalafil CAS No.: 385769-84-6 98% bohloeki min.bakeng sa lisebelisoa tsa tlatsetso
Lihlahisoa tsa lihlahisoa
| Lebitso la sehlahisoa | Amino Tadalafil |
| Lebitso le leng | (6R,12aR)-2-Amino-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[ 3,4-b]indole-1,4-dione;AminoTadalafil(6R,12Ar)-2-Amino-6-(1,3-Benzodioxol-5-Yl)-2,3,6,7,12,12A -Hexahydropyrazino[1',2':1,6]Pyrido[3,4-B]Indole-1,4-Dione;(6R,12aR) -2-Amino-6-(benzo[d][1,3] ]dioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-1,4-dione;(6R ,12aR) -2-amino-6-(benzo[d][1,3]dioxol-5-yl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3] ,4-b]indole-1,4(6H,7H)-dione |
| Nomoro ea CAS. | 385769-84-6 |
| Mokhoa oa limolek'hule | Setšoantšo sa C21H18N4O4 |
| Boima ba molek'hule | 390.39 |
| Bohloeki | 98.0% |
| Ponahalo | Phofo e tšoeu ho isa ho e tšoeu |
| Kopo | Tlatsetso ea Lijo tse tala |
Kenyelletso ea sehlahisoa
Amino Tadalafil ke motsoako o tšoanang le oa Tadalafil, 'me lihlopha tse ling tse sebetsang mohahong oa eona li nkeloa sebaka ke lihlopha tsa amino.Ke PDE5 inhibitor mme e na le liphello tsa pharmacological tse tšoanang le Tadalafil.E sebelisoa haholo-holo bakeng sa phekolo ea ho se sebetse ha erectile dysfunction (ED).Ha e bapisoa le Tadalafil, Amino Tadalafil e na le tekanyo e fokolang ea metabolism 'meleng, kahoo e ka ba le phello e tšoarellang nako e telele.
Sebopeho
(1) Khetho e phahameng: Amino Tadalafil e na le khetho e phahameng bakeng sa PDE5, e nang le kamano e phahameng haholo bakeng sa PDE5 ho feta tse ling tse nyenyane tsa PDE.Sena se bolela hore Amino Tadalafil e ka thibela ka katleho mosebetsi oa enzyme ea PDE5, ho khothalletsa phallo ea mali lithong tsa banna tsa ho ikatisa le ho ntlafatsa matšoao a erectile dysfunction (ED).
(2) Phello e tšoarellang nako e telele: Amino Tadalafil e na le tekanyo e fokolang ea metabolism 'meleng, e lumellang hore e hlahise phello ea nako e telele ea meriana, e tšoarellang ho fihlela lihora tsa 36.Sena se etsa hore Amino Tadalafil e be moriana oa phekolo oa ED oa nako e telele, o sa hlokeng ho nkoa khafetsa.
(3) Litla-morao tse fokolang: Amino Tadalafil e na le litla-morao tse fokolang ha li bapisoa le Tadalafil, tse kang hlooho ea hlooho, le bothata ba mala.Ka lebaka la khetho ea eona e phahameng, Amino Tadalafil e ka qoba ho sebelisana ka katleho le li-subtypes tse ling tsa PDE, ho fokotsa liketsahalo tsa litla-morao.
(4) Litebello tse pharaletseng tsa kopo: Ntle le ho phekola ED, Amino Tadalafil e ka boela ea sebelisoa ho phekola mafu a mang a kang khatello ea mali ea methapo ea mali.Sena se etsa hore Amino Tadalafil e be le tebello e pharaletseng ea ts'ebeliso nakong e tlang.
Lisebelisoa
Amino Tadalafil ke motsoako o entsoeng lilemong tsa morao tjena, o nang le mohaho o tšoanang le oa Tadalafil, empa lihlopha tse ling tsa sebopeho sa eona li nkeloa sebaka ke lihlopha tsa amino.Hona joale, Amino Tadalafil ha e e-s'o amoheloe bakeng sa tšebeliso ea meriana, kahoo kopo ea eona lefapheng la bongaka e batla e lekanyelitsoe.Leha ho le joalo, liphuputso tse ling li bontšitse hore motsoako ona o na le monyetla o moholo oa ho sebelisoa.
Amino Tadalafil ke PDE5 inhibitor, e nang le phello e tšoanang ea meriana joaloka Tadalafil.E ka ntlafatsa matšoao a erectile dysfunction (ED) ka ho khothalletsa phallo ea mali lithong tsa banna tsa ho ikatisa ka ho thibela mosebetsi oa enzyme ea PDE5.Ha e bapisoa le Tadalafil, Amino Tadalafil e na le sekhahla sa metabolism butle 'meleng, se ka bang le phello e tšoarellang.Sena se etsa hore Amino Tadalafil e be le monyetla o moholo oa ho phekola ED.
Ntle le moo, Amino Tadalafil e ka sebelisoa hape ho phekola mafu a mang, joalo ka khatello ea mali ea methapo ea mali.Liphuputso tse ling li bonts'itse hore li-inhibitors tsa PDE5 li ka alafatsa methapo ea mali ea pulmonary, ka hona ho ntlafatsa matšoao a bakuli ba nang le khatello ea mali ea methapo ea methapo.Hobane Amino Tadalafil e na le phello e ts'oanang ea pharmacological joaloka Tadalafil, e ka boela ea sebelisoa ho phekola khatello ea mali ea methapo ea mali.
Ka kakaretso, Amino Tadalafil e na le bokhoni bo boholo ba kopo, empa ho hlokahala liteko tse eketsehileng tsa kliniki ho fumana polokeho le katleho ea eona.Haeba liteko tsena li fana ka liphello tse ntle, Amino Tadalafil e ka 'na ea e-ba lithethefatsi tse ncha bakeng sa phekolo ea ED le pulmonary arterial hypertension, ho fana ka mekhoa e mengata ea phekolo bakeng sa lingaka tsa meriana le bakuli.
