Ha batho ba phehella bophelo bo bolelele le ho thibela botsofali, kamehla ba batla lintho tse ncha le li-supplement tsa lijo. Calcium alpha-ketoglutarate (CaAKG) ke ntho e ntseng e hapa tlhokomelo sechabeng sa bophelo bo botle le boiketlo. Motsoako ona o ithutiloe ka bokhoni ba oona ba ho lelefatsa bophelo le ho loantša liphello tsa botsofali, e leng se etsang hore e be tlatsetso e khahlisang lefatšeng la li-supplement tsa lijo. Joale, hantle-ntle calcium alpha-ketoglutarate ke eng? E sebetsa joang?
Calcium Alpha ketoglutarate (AKG) ke metabolite e mahareng ea potoloho ea tricarboxylic acid mme e nka karolo ho kopanyeng li-amino acid, livithamine, le li-acid tsa organic le metabolism ea matla. E ka sebelisoa e le tlatsetso ea lijo 'me e na le menyetla e mengata ea ts'ebeliso. Ntle le mesebetsi ea eona ea baeloji 'meleng oa motho, calcium alpha-ketoglutarate e boetse e sebelisoa haholo lefapheng la meriana 'me e fetohile karolo ea bohlokoa ea lihlahisoa tse ngata tsa bophelo bo botle le litharollo tsa bongaka.
Kamoo calcium alpha-ketoglutarate e sebetsang kateng
Ntlha ea pele,calcium alpha-ketoglutaratee bapala karolo ea bohlokoa ho metabolism ea matla. Jwalo ka sehlahisoa se mahareng sa potoloho ea tricarboxylic acid (TCA cycle), calcium α-ketoglutarate e nka karolo ts'ebetsong ea tlhahiso ea matla ka hare ho sele. Ka potoloho ea TCA, limatlafatsi tse kang lik'habohaedreite, mafura le liprotheine lia oxidized le ho bola ho hlahisa ATP (adenosine triphosphate) ho fana ka matla bakeng sa lisele. Jwalo ka karolo ea bohlokoa potolohong ea TCA, calcium α-ketoglutarate e ka khothaletsa metabolism ea matla a sele, ea eketsa boemo ba matla a 'mele, ea thusa ho eketsa matla a 'mele le mamello, le ho ntlafatsa mokhathala oa' mele.
Taba ea bobeli, calcium α-ketoglutarate e bapala karolo ea bohlokoa ho metabolism ea amino acid. Li-amino acid ke li-unit tsa motheo tsa protheine, 'me calcium α-ketoglutarate e ameha phetohong le metabolism ea li-amino acid. Ts'ebetsong ea ho fetola li-amino acid hore e be li-metabolite tse ling, calcium α-ketoglutarate e fetoha ka li-amino acid ho hlahisa li-amino acid tse ncha kapa li-α-keto acid, ka hona e laola ho leka-lekana le ts'ebeliso ea li-amino acid. Ho phaella moo, calcium α-ketoglutarate e ka boela ea sebetsa e le substrate ea oxidation bakeng sa li-amino acid, ea nka karolo metabolism ea oxidative ea li-amino acid, 'me ea hlahisa matla le carbon dioxide. Ka hona, calcium α-ketoglutarate e bohlokoa haholo ho bolokeng homeostasis ea li-amino acid le metabolism ea protheine 'meleng.
Ho phaella moo, calcium alpha-ketoglutarate e sebetsa e le antioxidant e tlosang li-free radical le ho sireletsa lisele tšenyong ea oxidative. Ka nako e ts'oanang, calcium α-ketoglutarate e ka boela ea laola ts'ebetso ea sesole sa 'mele, ea khothaletsa ts'ebetso le ho ata ha lisele tsa 'mele, le ho ntlafatsa ho hanyetsa ha' mele mafung le tšoaetsong. Ka hona, calcium α-ketoglutarate e bohlokoa haholo ho bolokeng botsitso ba 'mele ba' mele le ho hanela mafu.
Lipatlisiso mabapi le liphello tsa botsofali
Botsofali bo re ama kaofela 'me ke sesosa sa kotsi bakeng sa mafu a mangata, 'me ho ea ka lipalo-palo tsa indasteri ea Medicare, monyetla oa ho tšoaroa ke lefu o eketseha ha botsofali bo ntse bo hola. E le ho fokotsa botsofali le ho fokotsa kotsi ea lefu ka katleho, lipatlisiso li sibolotse ntho e sireletsehileng le e sebetsang e ka amang botsofali - calcium alpha-ketoglutarate.
Calcium alpha-ketoglutarate ke metabolite ea bohlokoa 'meleng oa rona, e tsejoang ka karolo ea sele potolohong ea Krebs, potoloho ea bohlokoa bakeng sa oxidation ea mafura a acid le amino acid, e lumellang mitochondria ho hlahisa ATP (ATP ke mohloli oa matla oa lisele).
Sena se kenyelletsa ho jarisoa ha ts'ebetso ea calcium alpha-ketoglutarate, kahoo calcium alpha-ketoglutarate e ka boela ea fetoloa glutamate ebe e fetoloa glutamine, e ka thusang ho susumetsa tlhahiso ea protheine le collagen (collagen ke protheine e nang le likhoele e etsang 1/3 ea protheine eohle 'meleng' me e thusa ho tšehetsa bophelo bo botle ba masapo, letlalo le mesifa).
Ponce De Leon Health, Inc., k'hamphani ea lipatlisiso tsa bophelo bo bolelele e shebaneng le ho fokotsa botsofali ba liphatsa tsa lefutso, e entse phuputso e laoloang ea lilemo tse ngata ea calcium alpha-ketoglutarate ho litoeba tse lilemong tse mahareng 'me ea fumana hore nako ea bophelo ba litoeba sehlopheng sa liteko e eketsehile ka 12%. Habohlokoa le ho feta, bofokoli bo fokotsehile ka 46% 'me nako ea bophelo bo botle e eketsehile ka 41%. Bopaki bo bontša hore tlatsetso ea alpha-ketoglutarate e kanna ea se ke ea eketsa nako ea bophelo feela empa hape ea eketsa nako ea bophelo bo botle ka bophara.
Calcium α-ketoglutarate, e le tlatsetso ea phepo e sebetsang ka mesebetsi e mengata, e na le menyetla e mengata ea ts'ebeliso lihlahisoa tsa tlhokomelo ea bophelo bo botle. Mesebetsi ea eona e fapaneng ea baeloji e kang antioxidant, anti-botsofali, taolo ea 'mele ea ho itšireletsa mafung le metabolism ea amino acid e etsa hore e be sesebelisoa se matla sa ho ntlafatsa bophelo bo botle ba batho. Ka temoho e ntseng e eketseha ea tlhokomelo ea bophelo bo botle le ho teba ha lipatlisiso tsa mahlale, ho lumeloa hore ts'ebeliso ea calcium ea α-ketoglutarate lefapheng la lihlahisoa tsa tlhokomelo ea bophelo bo botle e tla fumana tlhokomelo le nts'etsopele e eketsehileng.
Tlhokomeliso: Sengoloa sena ke sa tlhahisoleseding e akaretsang feela mme ha sea lokela ho nkuwa e le keletso efe kapa efe ya bongaka. Tse ding tsa tlhahisoleseding ya poso ya blog di tswa Inthaneteng mme ha se tsa botsebi. Webosaete ena e ikarabella feela bakeng sa ho hlophisa, ho hlophisa le ho hlophisa dihlooho. Morero wa ho fetisa tlhahisoleseding e eketsehileng ha o bolele hore o dumellana le maikutlo a yona kapa o tiisa bonnete ba dikahare tsa yona. Kamehla buisana le setsebi sa tlhokomelo ya bophelo pele o sebedisa ditlatsetso dife kapa dife kapa o etsa diphetoho tsamaisong ya hao ya tlhokomelo ya bophelo.
Nako ea poso: Phato-20-2024
