7,8-Dihydroxyflavone ke motsoako oa tlhaho o fumanoang limela o fumane tlhokomelo e kholo bakeng sa melemo ea eona e ka bang teng mosebetsing oa boko le mohopolo. Motsoako ona oa flavone ke oa sehlopha sa lik'hemik'hale tse bitsoang flavonoids, tse tsejoang ka thepa ea tsona ea antioxidant le anti-inflammatory. Lipatlisiso li bonts'itse hore 7,8-dihydroxyflavone e ka ba le litlamorao tse ngata tse ntle bokong.
7,8-Dihydroxyflavone ke motsoako o matla le o feto-fetohang oa lelapa la flavonoid. Li-Flavonoids ke metsoako ea tlhaho e ajoang haholo limeleng 'me e phetha karolo ea bohlokoa lits'ebetsong tse fapaneng tsa tlhaho. E 'ngoe ea litšoaneleho tse tsotehang tsa 7,8-dihydroxyflavone ke bokhoni ba eona ba ho sebelisana le ho laola liprotheine le li-enzyme 'meleng, tse tsositseng thahasello e kholo sechabeng sa saense.
Lipatlisiso li bontšitse hore motsoako oa 7,8-dihydroxyflavone o na le melemo ea bophelo bo botle, e nang le thepa ea antioxidant, anti-inflammatory le neuroprotective. Har'a tsona, ts'ebetso e matla ea antioxidant ea 7,8-dihydroxyflavone e e nolofalletsa ho senya li-radicals tse kotsi 'meleng le ho thibela khatello ea oxidative ho baka tšenyo ea lisele le mafu a fapaneng. Lipatlisiso tse entsoeng ho fihlela joale ka 7,8-dihydroxyflavones lia khothatsa, empa lipatlisiso tse ngata lia hlokahala ho fumana katleho le polokeho ea 7,8-dihydroxyflavones bakeng sa ho sebelisoa ho batho. Leha ho le joalo, motsoako ona oa flavonoid o na le ts'episo e kholo e le tlatsetso ea lijo kapa moemeli oa lithethefatsi nakong e tlang.
7,8-Dihydroxyflavone ke motsoako oa tlhaho, oo hape o tsejoang e le 7,8-DHF, o fumaneng tlhokomelo e ngata lilemong tsa morao tjena ka melemo ea oona e ka bang teng bophelong ba batho.
Motsoako ona oa tlhaho ke oa lelapa la flavonoid 'me o fumanoa limela tse fapaneng, ho kenyelletsa le motso oa Scutellaria baikalensis.
1. Ntlafatsa ts'ebetso ea kelello
Lipatlisiso li bontša hore motsoako ona o sebetsa e le TrkB agonist, ho bolelang hore e kenya tšebetsong li-receptor tsa TrkB bokong. Li-receptor tsena li na le boikarabello ba ho khothaletsa kholo le ho phela ha li-neurone, hammoho le ho ntlafatsa polasetiki ea synaptic - bokhoni ba boko ba ho ikamahanya le maemo le ho fetoha. Ka ho susumetsa li-receptor tsa TrkB, 7,8-dihydroxyflavone e bontšitsoe ho ntlafatsa mohopolo le kutloisiso. Sena se etsa hore e be sesebelisoa sa kalafo se ka thusang ho alafa mafu a neurodegenerative joalo ka lefu la Alzheimer's.
2. Phello ea ho imeloa kelellong
Ka ho kenya tšebetsong li-receptor tsa TrkB, komporo e khothaletsa kholo ea li-neurone tse ncha ho hippocampus, sebaka sa boko se amehang taolong ea maikutlo. Boithuto ba mohlala oa liphoofolo bo bonts'itse hore 7,8-dihydroxyflavone e ka fokotsa matšoao a khatello ea maikutlo le ho matlafatsa ho hanyetsa khatello ea maikutlo. Liphuputso tsena li fana ka maikutlo a hore motsoako ona o ka sebelisoa e le mokhoa oa tlhaho ho fapana le li-antidepressants tsa setso.
3. Lintho tse khahlanong le ho ruruha le matla a antioxidant
7,8-Dihydroxyflavone ke antioxidant e matla e thusang ho sireletsa lisele khatellong ea oxidative e bakoang ke li-radicals tsa mahala. Tšireletso ena e fokotsa kotsi ea lefu le sa foleng 'me e liehisa mokhoa oa ho tsofala.
Ho ruruha ha boko ho ka tlatsetsa ho nts'etsopele le tsoelo-pele ea mafu a sa tšoaneng a methapo ea kutlo, ho akarelletsa lefu la Parkinson le multiple sclerosis. Lipatlisiso li bontša hore 7,8-DHF e na le lintho tse thibelang ho ruruha tse thusang ho fokotsa ho ruruha bokong le ho thibela neurodegeneration. Ka ho thibela tlhahiso ea limolek'hule tsa pro-inflammatory, motsoako o ka ba le monyetla oa ho fokotsa matšoao le ho liehisa tsoelo-pele ea mafu ana a fokolisang.
4. E na le Monyetla oa ho Phekola Matšoenyeho a Matšoenyeho
Liphuputso tsa liphoofolo li bontšitse hore motsoako o ka fokotsa boitšoaro bo kang ba ho tšoenyeha ka ho kenya tšebetsong li-receptor tsa TrkB ho amygdala, sebaka sa boko se amehang karabelong ea tšabo le matšoenyeho. Ka ho fetola mosebetsi oa li-receptor tsena, 7,8-dihydroxyflavones e ka fana ka mokhoa oa tlhaho le o sebetsang oa ho laola matšoenyeho ntle le litla-morao tse amanang le meriana ea setso e khahlanong le ho tšoenyeha.
Pele re kenella mehloling ea lijo, ha re utloisise hore na 7,8-dihydroxyflavone ke eng. Ke flavonoid ea tlhaho ea tlhaho eo e leng ea sehlopha sa flavonoids. Li-Flavonoids ke metsoako ea limela e tsejoang ka thepa ea eona ea antioxidant, e thusang ho sireletsa lisele ho li-radicals tsa mahala tse kotsi.
Joale, ha re hlahlobeng lijo tse ling tse nang le palo e phahameng ea 7,8-dihydroxyflavone:
1. Litholoana tsa Citrus
E 'ngoe ea mehloli e metle ka ho fetisisa ea 7,8-dihydroxyflavones ke litholoana tsa lamunu tse kang lilamunu, lisirilamunu, li-grapefruit le lime. Litholoana tsena ha li na vithamine C feela e ngata, empa hape li na le mefuta e mengata ea flavonoids, ho akarelletsa le 7,8-dihydroxyflavone.
2. monokotsoai
Monokotšoai o kang blueberries, fragole, raspberries le blackberries li tsebahala ka li-antioxidant tse ngata. Litholoana tsena tse monate le tsona ke mohloli o motle oa 7,8-dihydroxyflavone, tse u fang melemo ea bophelo bo botle habeli.
3. Tsokolate e Lefifi
Litaba tse monate ho barati ba chokolete! Chokolete e lefifi, haholo-holo e nang le cocoa e ngata, e na le palo e phahameng ea 7,8-dihydroxyflavonoids. Leha ho le joalo, khetha mefuta e nang le tekanyo e fokolang ea tsoekere e ekelitsoeng ho fumana melemo e feletseng.
4. Tee e tala
Ntle le ho ba seno se tsebahalang, tee e tala e boetse e na le li-flavonoids tse ngata, ho kenyelletsa le 7,8-dihydroxyflavone. Tšebeliso ea kamehla ea tee e tala e ka thusa ho eketsa tlhahiso ea hau ea antioxidant le ho tšehetsa bophelo bo botle ka kakaretso.
5. Soya
Haeba u batla mohloli oa semela oa 7,8-dihydroxyflavone, soya ke khetho e ntle haholo. Hase feela hore li na le protheine e ngata, empa li boetse li na le li-flavonoids tse sa tšoaneng tse tlatsetsang thepa ea tsona e molemo.
6. Meroho e makhasi a matala
Meroho e kang khale, spinach le broccoli ha e na lik'hilojule tse fokolang feela, empa hape e na le li-antioxidants tse ngata. Meroho ena e mahlaku ke mohloli o babatsehang oa 7,8-dihydroxyflavone, hammoho le limatlafatsi tse ling tsa bohlokoa.
7. Veine e khubelu
Thabang! Ho noa veine e khubelu ka mokhoa o itekanetseng ho na le mofuta oa flavonoid o bitsoang resveratrol, o kenyelletsang 7,8-dihydroxyflavone. Ho nahanoa hore motsoako ona o tlatsetsa melemo ea pelo e amanang le tšebeliso ea veine e khubelu e itekanetseng.
Ho kenyelletsa lijo tsena lijong tsa hau ho ka u fa melemo e mengata e amanang le 7,8-dihydroxyflavone.
7,8-Dihydroxyflavone, e tsejoang hape e le DHF kapa baicalein, ke flavonoid ea tlhaho e fumanehang limela tse fapaneng, ho kenyeletsoa motso oa Scutellaria baikalensis. Motsoako ona o fumane tlhokomelo e ngata lilemong tsa morao tjena bakeng sa melemo ea eona ea bophelo bo botle le thepa ea phekolo. Leha ho le joalo, ha ho nahanoa ka polokeho ea ntho leha e le efe, ke habohlokoa ho hlahloba bopaki bo teng ba saense. Joale, na 7,8-dihydroxyflavone e bolokehile?
Mabapi le polokeho ea eona, lipatlisiso tse fokolang li entsoe mabapi le tšebeliso e tobileng ea batho ea 7,8-dihydroxyflavone. Ka hona, ho bua mantsoe a tiileng mabapi le polokeho ea eona ho thata. Leha ho le joalo, lithuto tsa liphoofolo li fane ka temohisiso ea bohlokoa mabapi le chefo e ka bang teng. Mefuta e fapaneng ea liphoofolo ha e tlalehe hore ha ho litla-morao tse bohlokoa kamora tsamaiso ea DHF, leha e le litekanyetso tse phahameng haholo. Sena se fana ka maikutlo a hore 7,8-dihydroxyflavone e ka mamelloa hantle, bonyane ka har'a litekanyetso tse ithutoang.
Leha ho le joalo, tlhokomeliso e tlameha ho sebelisoa ha ho etsoa liqeto tse thehiloeng lithutong tsa liphoofolo feela. Liphello tsa lintho li ka 'na tsa fapana haholo pakeng tsa mefuta ea liphoofolo, ka hona, ho hlokahala hore ho be hlokolosi ha ho fetisetsa liphello ho batho. Ho feta moo, khaello ea lithuto tse felletseng tsa nako e telele tsa batho li thibetse tlhahlobo e hlakileng ea polokeho ea eona.
7,8-Dihydroxyflavone (7,8-DHF) ke flavonoid ea tlhaho e fumaneng tlhokomelo e ngata bakeng sa melemo ea eona ea bophelo bo botle, leha ho le joalo, ho bohlokoa haholo ho tseba litekanyetso le likhothaletso tse khothaletsoang ha u sebelisa 7,8-DHF. bohlokoa.
Ke habohlokoa ho buisana le setsebi sa tlhokomelo ea bophelo ha ho tluoa tabeng ea litekanyetso tsa 7,8-DHF, kaha litekanyetso tse loketseng li ka fapana ho latela lintlha tse ngata tse kang lilemo, boima ba 'mele le maemo a itseng a bophelo bo botle. Boithuto ba hajoale bo fana ka maikutlo a mefuta e mengata ea litekanyetso tsa litekanyetso, hangata 20 ho isa ho 60 mg ka letsatsi. Leha ho le joalo, ho lokela ho hlokomeloa hore litlhahiso tsena ha lia behoa ka majoe 'me li ka fetoha ha bopaki bo bongata ba saense bo bokelloa.
Ha u reka li-supplement tsa lijo tse 7,8-DHF, ho bohlokoa ho khetha moetsi ea tšepahalang le ea tšepahalang ho netefatsa polokeho le katleho ea sehlahisoa. Ho bala maikutlo a bareki le ho hlahloba liteko tsa laboratori tsa motho oa boraro le hona ho ka thusa ho tseba ho tšepahala ha sehlahisoa. Ho bohlokoa haholo ho latela keletso ea setsebi sa tlhokomelo ea bophelo. Ba tla khona ho fana ka tataiso ea motho ka mong ho latela nalane ea hau ea bongaka le maemo a hajoale a bophelo bo botle. Kamehla ho kgothaletswa ho qala ka tekanyo e tlaase ka ho fetisisa e sebetsang mme butle-butle e eketsehe kamoo ho hlokahalang tlas'a tlhokomelo ea setsebi sa tlhokomelo ea bophelo.
Pele o kenyelletsa 7,8-DHF lenaneong la hau la letsatsi le letsatsi, ho bohlokoa ho ela hloko litla-morao life kapa life tse ka bang teng kapa litšebelisano tsa lithethefatsi. Le hoja 7,8-DHF ka kakaretso e mamelloa hantle, batho ba bang ba ka ’na ba e-ba le bothata bo fokolang ba mala kapa ba hanana le bona. Hape, etsa bonnete ba hore u tsebisa setsebi sa tlhokomelo ea bophelo ka meriana leha e le efe kapa li-supplement tseo u li noang hona joale ho qoba tšebelisano leha e le efe e ka bang teng. Hopola hore ho nka li-supplement leha e le life ho lokela ho lula ho le tlas'a tataiso ea setsebi sa bophelo bo botle ho ntlafatsa bophelo ba hau.
P: Ho nka nako e kae hore 7,8-dihydroxyflavoneor e sebetse?
A: Lebelo leo 7,8-dihydroxyflavone (7,8-DHF) e sebetsang ka lona le ka fapana ho latela lintlha tse 'maloa. Lithutong tsa mahlale, 7,8-DHF e bonts'itse hore e na le litlamorao tse fapaneng, joalo ka ho khothaletsa tokollo ea "neurotrophic factor" le "neuroprotection". Nako eo e e nkang hore litlamorao tsena li hlahe e ka tloha ho lihora ho isa ho matsatsi kapa ho feta, ho latela mokhoa o ikhethileng oa ts'ebetso le sepheo sa motsoako.
Boitlhotlhollo: Sengoliloeng sena ke sa merero ea tlhahisoleseling feela mme ha sea lokela ho nkuoa e le keletso ea bongaka. Kamehla buisana le setsebi sa tlhokomelo ea bophelo pele u sebelisa li-supplement kapa ho fetola mokhoa oa hau oa tlhokomelo ea bophelo.
Nako ea poso: Jul-04-2023
