Moetsi oa phofo ea 7,8-Dihydroxyflavone (7,8-DHF) Nomoro ea CAS: 38183-03-8 Bohloeki ba 98.0% bonyane bakeng sa metsoako ea tlatsetso
Video ea Sehlahisoa
Liparamente tsa Sehlahisoa
| Lebitso la sehlahisoa | 7,8-Dihydroxyflavone |
| Lebitso le leng | 7,8-DIHYDROXYFLAVONE; 7,8-dihydroxy-2-phenyl-4-benzopyrone; DIHYDROXYFLAVONE, 7,8-(RG); 7,8-Dihydroxyflavone hydrate; 7,8-dihydroxy-2-phenyl-1-benzopyran-4-e le 'ngoe |
| Nomoro ea CAS | 38183-03-8 |
| Foromo ea limolek'hule | C15H10O4 |
| Boima ba limolek'hule | 254.24 |
| Bohloeki | 98.0% |
| Ponahalo | Phofo e mosehla |
| Kopo | Lisebelisoa tse Tala tsa Tlatsetso ea Lijo |
Selelekela sa sehlahisoa
7,8-Dihydroxyflavone, e tsejoang hape e le 7,8-DHF, ke flavonoid e hlahang ka tlhaho e fumanoang limela tse fapaneng, ho kenyeletsoa le Tridacna tridacna. E tsebahala ka thepa ea eona ea antioxidant le neurotrophic, e 'ngoe ea likarolo tse khahlisang ka ho fetisisa tsa 7,8-dihydroxyflavone ke bokhoni ba eona ba ho tšehetsa bophelo bo botle ba boko le ho ntlafatsa ts'ebetso ea kelello. Lipatlisiso li bontša hore motsoako ona o sebetsa e le neurotrophin e matla, o susumetsa kholo le ho phela ha li-neuron bokong. Lithuto liphoofolong tsa laboratori li bontšitse hore 7,8-DHF e ntlafatsa haholo bokhoni ba ho hopola le ho ithuta. Ka ho khothaletsa ho thehoa ha likhokahano tse ncha tsa synaptic le ho ntlafatsa puisano lipakeng tsa lisele tsa boko, motsoako ona o tšepisa ho notlolla bokhoni ba rona ba kelello. Ho feta moo, 7,8-dihydroxyflavone e sebelisana le li-receptor tsa serotonin tsa boko, tse amehang taolong ea maikutlo. Ka ho fetola li-receptor tsena, e ka khona ho fokotsa matšoao a matšoenyeho le khatello ea maikutlo.
Tšobotsi
(1) Bohloeki bo phahameng: 7,8-Dihydroxyflavone e ka fumana dihlahiswa tse hlwekileng haholo ka ho ntsha dintho tsa tlhaho le tshebetso ya tlhahiso e ntle. Bohloeki bo phahameng bo bolela ho fumaneha ha dihlahiswa hantle le dikarabelo tse fokolang tse mpe.
(2) Polokeho: 7,8-Dihydroxyflavone ke sehlahisoa sa tlhaho se pakiloeng hore se bolokehile ho batho. Ka har'a tekanyo ea tekanyo, ha e na chefo kapa litla-morao.
(3) Botsitso: 7,8-Dihydroxyflavone e na le botsitso bo botle mme e ka boloka ts'ebetso le phello ea eona tlas'a maemo a fapaneng a tikoloho le polokelo.
(4) Ho bonolo ho monya: 7,8-Dihydroxyflavone e ka monngoa kapele ke 'mele oa motho, ea kena ka har'a potoloho ea mali ka har'a mala, 'me ea ajoa liseleng le lithong tse fapaneng.
Likopo
7, 8-DHF, e le sesebelisoa se sebetsang hantle sa ho matlafatsa lisele tse nyane tsa TrkB receptor, e ka bapala karolo ea tšireletso ea li-neuron, tsosoloso ea li-neuron, taolo ea polasetiki ea synaptic, jj. ka ho etsisa tlamo e itseng ea BDNF ho TrkB le ho kenya tšebetsong litsela tsa matšoao a tlase, e le ho ntlafatsa haholo matšoao a ho ithuta maikutlong le ho fokotseha ha mohopolo oa sebaka, ho fokotseha ha bokhoni ba kelello, ho fokotseha ha ts'ebetso ea 'mele le matšoao a mang a lefu la tsamaiso ea methapo joalo ka lefu la Alzheimer kapa mehlala ea liphoofolo tse tsofalang, le ho fokotsa mefuta e amanang le lefu la kelello le liphoofolo tse nonneng. Ho sa le joalo, ho fihlela joale, ha ho na litla-morao tse kotsi tse kholo tsa 7,8-DHF tse fumanoeng liphoofolong tsa liteko. 7,8-DHF e na le bokhoni bo boholo le bohlokoa ho thibelong le kalafong ea mathata a amanang le BDNF/TrkB.
