'Mele ea rona e lula e intlafatsa boemong ba sele, e nkela lisele tsa khale le tse senyehileng sebaka ka tse foreshe. Ts'ebetso ena ea ho nchafatsa lisele e bohlokoa ho boloka bophelo ba rona bo botle le matla a rona ka kakaretso. Molek'hule ea bohlokoa e bapalang karolo ea bohlokoa ts'ebetsong ena ke NAD. NAD ke coenzyme e amehang liketsong tse fapaneng tsa metabolism 'meleng, ho kenyeletsoa tlhahiso ea matla, tokiso ea DNA le tsosoloso ea lisele. Joale re kenyelletsa NAD joang kemisong ea rona ea letsatsi le letsatsi?
NADke coenzyme e fumanoang sele e 'ngoe le e 'ngoe ea 'mele ea rona 'me e bapala karolo ea bohlokoa lits'ebetsong tse fapaneng tsa baeloji 'meleng oa rona. E ameha mesebetsing e kang tlhahiso ea matla, tokiso ea DNA le tlhahiso ea liphatsa tsa lefutso. Ha re ntse re tsofala, maemo a NAD liseleng aa theoha, e leng se lebisang ho fokotseng matla a lisele le ho pepesehela mafu a amanang le botsofali haholo.
Leha ho le jwalo, ho na le ditsela tsa ho eketsa maemo a NAD ka tlhaho mmeleng ya rona, e nngwe ya tsona ke ka dijo tsa rona. Dijo tse itseng di na le dimolekhule tse ngata tsa pele ho NAD, tse fetolelwang ho NAD diseleng tsa rona. Ho kenyelletsa dijo tsena dijong tsa rona ho ka thusa ho tlatsa maemo a NAD mme mohlomong ho diehisa tshebetso ya botsofali.
Ntle le ho eketsa matla, NAD e ka boela ea thusa ho khothaletsa botsofali bo phetseng hantle, ho ntlafatsa ts'ebetso ea kelello le ho thibela lefu la pelo.
1. Ntlafatsa matla a sele:
E 'ngoe ea melemo e hlahelletseng ea NAD ke bokhoni ba eona ba ho ntlafatsa tlhahiso ea matla a sele. Ha re ntse re tsofala, maemo a NAD 'meleng ea rona a fokotseha ka tlhaho, a sitisa tlhahiso ea ATP, e leng se lebisang mokhathaleng le ho fokotseha ha mamello. Ka ho tlatsa maemo a NAD ka li-supplement tsa lijo kapa ka ho kenya tšebetsong li-enzyme tse khothalletsang tlhahiso ea NAD, re ka khutlisa maemo a matla, e leng se fellang ka matla a eketsehileng le ts'ebetso e ntlafetseng ea 'mele le ea kelello.
2. Tokiso ea DNA le botsitso ba genome:
Tšenyo e bokellaneng ea DNA ke e 'ngoe ea mabaka a bohlokoa a susumetsang ts'ebetso ea botsofali, e lebisang ho nts'etsopele ea mafu a amanang le botsofali. Karolo ea bohlokoa ea NAD joalo ka motšehetsi oa mechini ea tokiso ea DNA e netefatsa ho bolokoa ha botsitso ba genome. Ka ho susumetsa tlhahiso ea NAD, re ka ntlafatsa bokhoni ba 'mele ba ho lokisa DNA e senyehileng, ka hona ra liehisa ts'ebetso ea botsofali le ho khothaletsa bophelo bo botle ka kakaretso.
3. E Ntlafatsa Bophelo bo Botle ba Metabolism:
Ho fokotseha ha metabolism ke phello ea tlhaho ea botsofali 'me hangata ho lebisa ho eketseheng ha boima ba' mele, ho hanyetsa insulin le mathata a metabolism. Lipatlisiso tsa morao tjena li bontšitse hore NAD e bapala karolo ea bohlokoa ho laoleng metabolism, haholo-holo ka sehlopha sa li-enzyme tse bitsoang sirtuins. Ka ho eketsa maemo a NAD, re kenya tšebetsong li-sirtuins tsena, re khothaletsa bophelo bo botle ba lisele, re ntlafatsa metabolism le ho fokotsa mathata a metabolism a amanang le botsofali.
4. Tšireletso ea Methapo ea Kelello le Botsofali ba Kelello:
Ho fokotseha ha tsebo ke ntho e tšoenyang batho ba baholo. Bokhoni ba NAD ba ho ntlafatsa ts'ebetso ea mitochondrial, ho fokotsa khatello ea oxidative, le ho eketsa tlhahiso ea lintho tse sireletsang methapo tse bitsoang li-neurotrophin li na le bokhoni bo boholo ba ho loantša ho fokotseha ha tsebo ho amanang le botsofali. Lithuto tse ngata li tlaleha hore maemo a phahameng a NAD a ntlafatsa ts'ebetso ea kelello le ts'ireletso ea methapo.
5. Lelefatsa bophelo:
Mesebetsi e mengata ea NAD lits'ebetsong tsa sele le ho boloka botsitso ba genome e kenya letsoho bokhoning ba eona e lemolek'hule ea bophelo bo boleleleLithuto tse 'maloa linthong tse phelang tsa mohlala tse kang liboko le litoeba li bontšitse hore ho eketsa kapa ho kenya tšebetsong NAD ho ka eketsa bophelo ba motho haholo. Leha phetolelo ea liphuputso tsena ho batho e ntse e ntse e fuputsoa, tebello e khahlisang ea ho lelefatsa bophelo ba motho bo phetseng hantle e na le tšepiso ea mekhoa ea nakong e tlang ea ho thibela botsofali.
NAD ke coenzyme e teng liseleng tsohle tse phelang, ehlile limolek'hule tsa NAD ha li teng ka ho toba lijong, empa lintho tse etellang pele NAD li teng ka tlhaho lijong, ho kenyeletsoa limela le liphoofolo.
Lisele tse 'meleng oa rona li hloka li-design tse itseng, tse bitsoang li-precursor tsa NAD, ho etsa NAD. Ha li kena 'meleng oa rona, li-precursor tsena li feta liphetohong tsa lik'hemik'hale liseleng ho etsa NAD. Li-precursor tsa tsona ke niacinamide, niacin, le tryptophan li ka fumanoa mehloling e fapaneng ea lijo. Lijo tse kang nama, tlhapi, lebese, linaoa, lijo-thollo, linate le peo li na le li-precursor tsena, tseo 'mele o ka li sebelisang ho etsa NAD.
Mehloli e meholo ea lijo tsa NAD e kenyelletsa nama, likhoho, litlhapi le lijo tse ling tsa limela.
1. Lijo tsa liphoofolo tse kang sebete sa nama ea khomo, khoho, nama ea khomo le nama ea kolobe:
Ntle le ho ba mohloli o motle oa niacin, sebete sa nama ea khomo se boetse se na le tšepe e ngata, vithamine B12 le zinki.
2. Khoho
Ntle le tekanyo ea eona ea niacin, khoho le eona ke khetho e ntle bakeng sa ho ntlafatsa bophelo bo botle ba mesifa le bophelo bo botle ka kakaretso ka lebaka la tekanyo ea eona e phahameng ea protheine.
3. Litlhapi
Hase feela hore e na le niacin, tlhapi e tsebahala ka ho ba le mafura a mangata a omega-3, a thusang ho ntlafatsa bophelo bo botle ba pelo.
4. Raese
Reise e sootho le e tšoeu ke lijo tsa bohlokoa tse fanang ka limatlafatsi tsa bohlokoa lijong tsa rona. Ntle le niacin, reise e sootho e ruile ka livithamine le liminerale tsa bohlokoa 'me e tsebahala haholo ka faeba ea eona e ngata ho feta reise e tšoeu.
5. Meroho e tala e kang ditamati, broccoli, spinach le asparagus
Ke li-supplement tse monate le tse nang le phepo. Hase feela hore li na le niacin, tamati hape ke mohloli o motle oa li-antioxidants, vithamine C le riboflavin. Ho kenyelletsa meroho ena lijong tsa hau ho netefatsa hore u fumana lintho tse tlang pele tseo u li hlokang bakeng sa tlhahiso ea NAD.
6. Lebese, chisi le yogurt
Khalase ea lebese la 1% e fana ka 0.2 mg ea niacin ka karolo e le 'ngoe. Ho phaella moo, lebese le boetse le na le protheine, calcium, zinki le riboflavin, e leng molemo bakeng sa bophelo bo botle ba masapo le ho thibela osteoporosis ho batho ba baholo.
Ho ja lijo tse nang le li-precursor tsa NAD ho ka thusa ho tšehetsa maemo a NAD 'meleng, empa ho ka 'na ha se ke ha lekana ka bohona ho tlatsa NAD ka botlalo. Li-precursor tsa NAD, tse kang nicotinamide riboside (NR) le nicotinamide mononucleotide (NMN), li fetoloa ho ba NAD 'meleng. Leha ho le joalo, ts'ebetso ea phetoho e ka ba e rarahaneng, 'me bokhoni ba' mele ba ho monya le ho sebelisa li-precursor tsena bo ka fapana.
Mabaka a mang, a kang lilemo, khatello ea maikutlo, meriana e itseng, le maemo a fapaneng a bophelo bo botle le 'ona a ka ama maemo a NAD. Kahoo ho phaella ho karolo ea bohlokoa ea ho boloka maemo a NAD ka lijo tse phetseng hantle, lintlha tse ling tsa mokhoa oa bophelo le tsona li hloka ho nahanoa. Lithuto li bontšitse hore boikoetliso ba kamehla bo ka eketsa maemo a NAD liseleng le lithong tse fapaneng, e leng se tlatsetsang botsofaling bo phetseng hantle. Ho robala ka ho lekaneng le ho laola maemo a khatello ea maikutlo le hona ho bohlokoa bakeng sa tlhahiso e ntle ea NAD le bophelo bo botle ka kakaretso.
Ho phaella moo, bakeng sa batho ba bang ba jang meroho feela kapa ba nang le lithibelo tsa lijo, li-supplement tsa NAD tse ka sebelisoang pele ho lijo li ka nahanoa, e leng se ka thusang batho ho fumana 'mele o phetseng hantle le ho liehisa ts'ebetso ea botsofali.
Tlhokomeliso: Sengoloa sena ke sa merero ea tlhahisoleseling feela 'me ha sea lokela ho nkoa e le keletso ea bongaka. Kamehla buisana le setsebi sa tlhokomelo ea bophelo pele u sebelisa li-supplement kapa u fetola mokhoa oa hau oa tlhokomelo ea bophelo.
Nako ea poso: Phato-31-2023
