Evodiamine ke motsoako oa tlhaho o fumanoang litholoana tsa semela sa Evodiamine, se tsoaletsoeng Chaena le linaheng tse ling tsa Asia. E 'nile ea sebelisoa meriana ea setso ea Chaena ka lilemo tse makholo ka lebaka la melemo ea eona ea bophelo bo botle. Har'a bona, evodiamine e na le bokhoni bo boholo ba ho laola ho ruruha le ho thusa ho theola boima ba 'mele. Lintho tsa eona tse khahlanong le ho ruruha li etsa hore e be mokhethoa oa bohlokoa bakeng sa ho phekola maloetse a sa tšoaneng a ho ruruha, ha bokhoni ba eona ba ho eketsa thermogenesis le ho khothalletsa lipolysis ho ka thusa ho laola boima ba 'mele.
Na u kile ua kopana le lentsoe "evodiamine" 'me ua ipotsa hore na ha e le hantle le bolela'ng? Evodiamine, e nkiloeng ho semela sa Evodiamine, ke motsoako oa tlhaho oa China le linaheng tse ling tsa Asia. Evodiamine ke ea sehlopha sa li-alkaloids tse tsejoang e le "quinazole alkaloids," metsoako e ntšitsoeng litholoana tse sa butsoang tsa semela mme e tsejoa ka thepa ea bona ea bongaka. Ka lilemo tse makholo, meriana ea setso ea Sechaena e sebelisitse matla a evodiamine ho imolla maloetse a sa tšoaneng.
Evodiamine e tsejoa ka thepa ea eona ea thermogenic, mokhoa oo 'mele o hlahisang mocheso, o ka ntlafatsang lebelo la metabolism le ho khothalletsa ho chesoa ha lik'halori. Ka ho eketsa thermogenesis, evodiamine e ka thusa ho chesa mafura le ho laola boima ba 'mele.
Ho ruruha ke karabelo ea tlhaho ea 'mele ho kotsi kapa tšoaetso. Leha ho le joalo, ho ruruha ho sa foleng ho ka lebisa mafung a sa tšoaneng. Ka ho fokotsa ho ruruha, evodiamine e ka thusa ho ntlafatsa bophelo bo botle ka kakaretso le ho fokotsa kotsi ea mafu a itseng.
Evodiamine e tsejoa ka thepa ea eona ea thermogenic. Thermogenesis e bolela mokhoa oa ho hlahisa mocheso 'meleng. Joale evodiamine e hlahisa mocheso joang ka ho khetheha?
E 'ngoe ea litsela tseo evodiamine e nang le liphello tsa eona tsa thermogenic ke ka ho kenya protheine e bitsoang transient receptor potential vanilloid subtype 1 (TRPV1). TRPV1 ke receptor e fumanoang haholo-holo tsamaisong ea methapo 'me e ameha ho laola mocheso oa' mele le metabolism. Ha evodiamine e tlama ho TRPV1, e baka letoto la likarabo tsa 'mele, ho kenyelletsa le ho eketseha ha litšenyehelo tsa matla le thermogenesis.
Evodiamine e fumanoe e susumetsa litšoelesa tsa adrenal ho lokolla li-catecholamine tse kang epinephrine le norepinephrine. Li-catecholamine li bapala karolo ea bohlokoa ho eketseheng ha lipolysis, ho aroloa ha mafura a bolokiloeng hore e be mafura a mahala a ka sebelisoang e le mohloli oa matla. Ts'ebetso ena e tsoela pele ho khothaletsa litlamorao tsa thermogenic tsa evodiamine.
Ho phaella moo, evodiamine e bontšitsoe ho thibela mosebetsi oa li-enzyme tse itseng tse amehang ho thehoa le ho boloka lisele tsa mafura. Ka mohlala, e thibela polelo ea peroxisome proliferator-activated receptor gamma (PPARγ), e leng ntho e ngotsoeng e khothalletsang ho bokella mafura ho adipocytes. Ka ho thibela mosebetsi oa PPARγ, evodiamine e ka thusa ho thibela ho thehoa ha lisele tse ncha tsa mafura le ho fokotsa ho boloka mafura.
1. Ho laola boima ba 'mele
E 'ngoe ea melemo e tsebahalang haholo ea evodiamine ke bokhoni ba eona e le thuso ea tlhaho ea ho laola boima ba' mele. Lipatlisiso li bontša hore evodiamine e ka susumetsa li-receptor tsa "mocheso" 'meleng ea rona, tse tsejoang e le li-receptor tsa nakoana tsa vanilloid 1 (TRPV1). Ka ho kenya li-receptor tsena, evodiamine e ka thusa ho eketsa thermogenesis le oxidation ea mafura, ka hona ho matlafatsa metabolism le ho lahleheloa ke boima ba 'mele. Ho phaella moo, e thibela ho hōla ha lisele tse ncha tsa mafura, ho tsoela pele ho tšehetsa thepa ea eona ea ho laola boima ba 'mele.
2. Lintho tse khahlanong le ho ruruha
Ho ruruha ho sa foleng ho amahanngoa le mathata a fapaneng a bophelo bo botle, ho kenyelletsa lefu la pelo, lefu la tsoekere, le tse ling. Evodiamine e nkoa e le ntho e ka thibelang ho ruruha ka lebaka la bokhoni ba eona ba ho thibela tlhahiso ea limolek'hule tsa pro-inflammatory. Liphuputso tse 'maloa li bontšitse hore evodiamine e ka thibela mosebetsi oa nuclear factor-κB (NF-κB), ntho e ka sehloohong e ngotsoeng e laolang polelo ea liphatsa tsa lefutso tsa pro-inflammatory. Ka ho thibela NF-κB, evodiamine e fokotsa ho ruruha ka ho fokotsa tlhahiso ea li-cytokine tsa ho ruruha tse kang interleukin-1β (IL-1β) le tumor necrosis factor-α (TNF-α).
3. Analgesic le thepa ea analgesic
Bohloko, hangata bo amahanngoa le ho ruruha, ke letšoao le leng la bohlokoa le ka amang boleng ba bophelo haholo. Lintho tsa analgesic tsa evodiamine li ithutile haholo, 'me li na le liphello tse khothatsang. Lipatlisiso li bontša hore evodiamine e ka kenya mocha oa nakoana oa ho amohela monyetla oa vanilloid 1 (TRPV1), o amehang phetisong ea matšoao a bohloko. Ka ho kenya likanale tsena, evodiamine e ka thibela maikutlo a bohloko le ho fana ka phomolo ho batho ba nang le mefuta eohle ea bohloko, ho akarelletsa le bohloko ba neuropathic le ho ruruha.
4. Bophelo bo botle ba pelo
Ho boloka tsamaiso ea pelo e phetseng hantle ke ea bohlokoa bakeng sa bophelo bo botle ka kakaretso. Evodiamine e bontšitsoe hore e na le litlamorao tse ntle tsa pelo, joalo ka ho fokotsa khatello ea mali le ho thibela ho bokellana ha liplatelete. Ka ho khatholla methapo ea mali le ho thibela mali hore a se ke a thehoa, evodiamine e ka thusa ho ntlafatsa phallo ea mali le ho fokotsa kotsi ea lefu la pelo, ho akarelletsa le lefu la pelo le stroke.
5. Bophelo bo Botle ba Malapeng
Evodiamine e ka ba le phello e ntle ho bophelo bo botle ba mala ka ho khothaletsa tšebetso ea tšilo ea lijo le ho fokotsa mathata a mala. Liphuputso li bontša hore evodiamine e ka susumetsa tlhahiso ea li-enzyme tsa tšilo ea lijo le ho ntlafatsa motility ea mala, 'me qetellong ea thusa tšilo ea lijo le ho imolla mathata a tšilo ea lijo. Ho feta moo, thepa ea evodiamine ea antimicrobial e ka thusang ho loants'a libaktheria tse kotsi le ho khothaletsa microbiome e phetseng hantle ea mala.
Evodiamine e rehelletsoe ka o mong oa mehloli ea eona ea mantlha ea limela, Evodia rutaecarpa, eo hangata e tsejoang e le Evodia fruit kapa Evodia rutaecarpa. Semela sena se tsoa Asia Bochabela 'me esale se sebelisoa meriana ea setso ea Machaena ka lilemo tse makholo. Litholoana tse sa butsoang tsa semela sa Evodia carota ke mohloli o ka sehloohong oa evodiamine. Mohlolo ona oa botanical o na le li-alkaloids tse 'maloa, ho akarelletsa le evodiamine, tse bontšitseng liphello tse molemo bophelong bo botle.
Mehloli e meng ea limela
Ho phaella ho Evodiamine, evodiamine e fumanoa mehloling e meng e mengata ea limela. Tsena li kenyelletsa Alstonia macrophylla, Evodia lepta le Euodia lepta, har'a tse ling. Limela tsena li hlaha libakeng tse fapaneng tsa Asia, ho kenyeletsoa Chaena, Japane le Thailand.
Hoa thahasellisa hore mehloli ena ea botanical ha e felle feela likarolong tse ikemetseng tsa semela. Le hoja litholoana tse sa butsoang e le tsona mohloli o ka sehloohong, evodiamine e ka boela ea ntšoa makhasi, likutu le metso ea limela tsena. Mehloli ena e mengata e fapaneng e fa bafuputsi le bo-rasaense menyetla e mengata ea ho hlahloba melemo e fapaneng ea bophelo bo botle le ts'ebeliso ea evodiamine.
●Tekanyetso e nepahetseng: Tekanyetso e nepahetseng ea evodiamine e itšetlehile ka lintlha tse 'maloa tse kang lilemo tsa mosebedisi, bophelo bo botle le maemo a mang a mangata. Hopola hore lihlahisoa tsa tlhaho ha li bolokehe kamehla, 'me litekanyetso li bohlokoa. Ho bohlokoa ho bala lileibole tsa lihlahisoa ka hloko 'me u buisane le setsebi sa tlhokomelo ea bophelo ho fumana hore na tekanyo e loketseng litlhoko tsa hau ke efe.
●Mehopolo ea Bophelo ba Botho: Ha u etsa qeto ea ho sebelisa tlatsetso efe kapa efe, ho kenyeletsoa evodiamine, ho bohlokoa ho nahana ka bophelo bo botle ba motho ka kakaretso, nalane ea bongaka le mamello ea motho. Ho feta moo, ela hloko litšebelisano tse ka bang teng tsa lithethefatsi 'me u nahane ka lintlha tsa bophelo bo botle ba motho ho eketsa melemo ea evodiamine ha u ntse u fokotsa likotsi tse amanang le tsona.
P: Evodiamine e laola ho ruruha joang?
A: Evodiamine e fumanoe e na le thepa e thibelang ho ruruha. E thibela tšebetso ea limolek'hule tse ling tsa ho ruruha, joalo ka nuclear factor-kappa B (NF-kB) le cyclooxygenase-2 (COX-2), tse phethang karolo ea bohlokoa ho ruruheng. Ka ho fokotsa tlhahiso ea limolek'hule tsena, evodiamine e thusa ho fokotsa ho ruruha 'meleng.
P: Na evodiamine e ka sebelisoa ho theola boima ba 'mele?
A: Evodiamine e 'nile ea batlisisoa bakeng sa liphello tsa eona tse ka bang teng ho theola boima ba' mele. Ho lumeloa hore e kenya tšebetsong tšebetso e bitsoang thermogenesis, e eketsang mocheso oa mantlha oa 'mele le sekhahla sa metabolism. Sena, ka lehlakoreng le leng, se ka eketsa litšenyehelo tsa khalori le ho thusa ho theola boima ba 'mele. Leha ho le joalo, ho hlokahala lipatlisiso tse eketsehileng ho theha katleho le polokeho ea evodiamine bakeng sa tahlehelo ea boima ba 'mele.
Boitlhotlhollo: Sengoloa sena ke sa tlhaiso-leseling e akaretsang feela 'me ha ea lokela ho nkuoa e le keletso efe kapa efe ea bongaka. Tse ling tsa litaba tsa poso ea blog li tsoa Marang-rang mme ha se setsebi. Sebaka sena sa marang-rang se na le boikarabello ba ho hlophisa, ho hlophisa le ho hlophisa lingoliloeng. Sepheo sa ho fetisa boitsebiso bo bongata ha se bolele hore u lumellana le maikutlo a eona kapa u tiisa bonnete ba litaba tsa eona. Kamehla buisana le setsebi sa tlhokomelo ea bophelo pele u sebelisa li-supplement leha e le life kapa u etsa liphetoho tsamaisong ea tlhokomelo ea bophelo.
Nako ea poso: Sep-26-2023
