Litlamorao tse khahlanong le ho ruruha tsa OEA li kenyelletsa bokhoni ba eona ba ho fokotsa tlhahiso ea limolek'hule tsa pro-inflammatory, ho thibela ts'ebetso ea lisele tsa 'mele, le ho fetola litsela tsa matšoao a bohloko.Mekhoa ena e etsa hore OEA e be sepheo se tšepisang sa phekolo bakeng sa phekolo ea ho ruruha le bohloko.
Oleoylethanolamide, kapa OEA ka bokhuts'oane, ke molek'hule ea lipid e etsahalang ka tlhaho eo e leng ea sehlopha sa metsoako e tsejoang ka hore ke fatty acid ethanolamides.’Mele ea rōna e hlahisa motsoako ona ka tekanyo e nyenyane, haholo-holo ka maleng a manyenyane, sebeteng le liseleng tse mafura.Leha ho le joalo, OEA e ka boela ea fumanoa mehloling e ka ntle, joalo ka lijo tse itseng le li-supplement tsa lijo.
OEA ho nahanoa hore e na le karolo ho metabolism ea lipid.Lipids li bohlokoa mesebetsing e mengata ea 'mele, ho kenyelletsa polokelo ea matla, ho kenya letsoho le tlhahiso ea lihormone.Metabolism e nepahetseng ea lipid e bohlokoa bakeng sa ho boloka bophelo bo botle, 'me OEA e ka thusa ho laola ts'ebetso ena. 
Lipatlisiso li fana ka maikutlo a hore OEA e ka ama khatello ea mali, molumo oa methapo ea mali, le mosebetsi oa ho qetela - lintlha tsa bohlokoa ho boloka methapo e phetseng hantle.Ka ho khothalletsa vasodilation le ho ntlafatsa phallo ea mali, OEA e ka thusa ho thibela ho phunya ha methapo e bakoang ke ho bokellana ha plaque.
OEA e kanna ea ba le thepa e thibelang ho ruruha le ho theola lipid, e ka bang le phello e ntle ho arteriosclerosis le mafu a amanang le ona.E bontšitsoe ho fokotsa sebopeho sa plaque, ho ruruha, le khatello ea oxidative mefuteng ea liphoofolo ea atherosclerosis.
Liphuputso li boetse li fumane hore OEA e ka ntlafatsa litlaleho tsa lipids tsa mali ka ho fokotsa triglycerides le low-density lipoprotein (LDL) k'holeseterole ha e ntse e eketsa k'holeseterole e phahameng-density lipoprotein (HDL).
1. Taolo ea takatso ea lijo le taolo ea boima ba 'mele
O mong oa melemo ea bophelo bo botle ea OEA ke bokhoni ba eona ba ho laola takatso ea lijo le ho khothaletsa taolo ea boima ba 'mele.Liphuputso li fumane hore OEA e ama ho lokolloa ha lihomone tsa tlala, e lebisang maikutlong a ho tlala le ho fokotsa ho ja lijo.Patlisiso e bonts'a hore OEA e thusa ho kenya li-receptor tse itseng ka har'a pampitšana ea mala, e eketsang ho khora.Ka ho laola takatso ea lijo, OEA e ka fana ka ts'ehetso ea bohlokoa bakeng sa boiteko ba ho laola boima ba 'mele.
2. Ho laola bohloko
Oleoylethanolamide (OEA) le eona e ithutoe bakeng sa karolo e ka bang teng ho mofetše.OEA e bontšitsoe ho kenya tšebetsong li-receptor tse itseng 'meleng, joalo ka peroxisome proliferator-activated receptor alpha (PPAR-α) le mofuta oa nakoana oa mofuta oa vanilloid 1 (TRPV1) receptor.Ts'ebetso ea li-receptor tsena e ka lebisa ho feto-fetoha ha matšoao a bohloko 'meleng.
OEA e fumanoe e na le litlamorao tsa analgesic mefuteng e fapaneng ea bohloko ea liphoofolo, ho kenyelletsa bohloko ba neuropathic le bohloko ba ho ruruha.Ho bontšitsoe ho fokotsa hyperalgesia (ke hore ho eketsa kutloisiso ea bohloko) le ho fokotsa boitšoaro bo amanang le bohloko.Mokhoa o mong o reriloeng oa ho nka khato ke bokhoni ba eona ba ho fokotsa ho lokolloa ha limolek'hule tsa pro-inflammatory le ho imolla ho ruruha, ka hona ho tlatsetsa maikutlong a bohloko.
3. Bophelo bo botle ba pelo
Bopaki bo hlahang bo bontša hore OEA e ka boela ea thusa bophelo bo botle ba pelo.OEA e bontšitsoe ho fokotsa ho ruruha, ho ntlafatsa kutloisiso ea insulin le ho laola maemo a k'holeseterole.Lintlha tsena li bohlokoa ho boloka bophelo bo botle ba pelo le ho fokotsa kotsi ea maemo a kang lefu la pelo le stroke.Bokhoni ba OEA joalo ka moemeli oa ts'ireletso ea pelo bo e etsa sepheo se ts'episang bakeng sa lipatlisiso tse ling tsa bongaka ba pelo.
4. Neuroprotection le Bophelo bo Botle ba Kelello
Liphello tsa OEA li fetela ka nģ'ane ho bophelo bo botle ba 'mele, kaha ho bontšitsoe hore e na le thepa ea neuroprotective.Boithuto bo bonts'itse hore OEA e ka thusa ho sireletsa lisele tsa boko khatellong ea oxidative le ho ruruha, e leng lintlha tsa bohlokoa mafung a fapaneng a neurodegenerative.Ho feta moo, OEA e hokahane le ho feto-fetoha ha li-neurotransmitters tse laolang maikutlo joalo ka serotonin.Ka hona, OEA e ka bapala karolo ho ts'ehetsa bophelo bo botle ba kelello le ho loants'a mathata a kang ho tšoenyeha le khatello ea maikutlo.
5. Lintho tse khahlanong le ho ruruha le ho fokotsa lipid
OEA e boetse e fumanoe e na le litlamorao tsa ho theola lipid, haholoholo ho triglyceride le maemo a cholesterol.E matlafatsa ho senyeha le ho felisoa ha triglycerides maling, kahoo e fokotsa maemo a triglyceride.OEA e boetse e bonts'itsoe ho fokotsa sebopeho sa k'holeseterole le ho monya, ka hona ho thusa ho theola maemo a cholesterol ea LDL.
Ntle le moo, OEA e bontšitsoe ho fokotsa ho ruruha ka ho fetola ts'ebetso ea matšoao a ho ruruha le li-cytokine liseleng tse fapaneng.E ka thusa ho thibela ho lokolloa ha limolek'hule tsa pro-inflammatory tse kang tumor necrosis factor-alpha (TNF-α) le interleukin-1 beta (IL-1β).
Oleoylethanolamide (OEA) ke ntho e tsoang ka tlhaho ea mafura a acid e sebetsang e le molek'hule e bontšang 'mele.E hlahisoa haholo ka maleng a manyane mme e thusa ho laola tekano ea matla, takatso ea lijo le metabolism ea lipid.
Moamoheli oa mantlha oa ketso ea OEA e bitsoa peroxisome proliferator-activated receptor alpha (PPAR-α).PPAR-α e hlahisoa haholo-holo lithong tse kang sebete, mala a manyenyane le lisele tsa adipose.Ha OEA e tlama PPAR-α, e kenya tšebetsong lets'oao la karabelo ea lik'hemik'hale tse nang le litlamorao tse ngata ho metabolism le taolo ea takatso ea lijo, e qetellang e lebisa ho fokotseng ho ja lijo le ho eketseha ha tšebeliso ea matla.
Ho feta moo, OEA e bontšitsoe ho hlohlelletsa ho senyeha, kapa lipolysis, ea mafura a bolokiloeng liseleng tsa adipose.Sena se finyelloa ka ho kenya li-enzyme tse thusang ho aroha ha triglycerides hore e be mafura a acid, a ka sebelisoang ke 'mele e le mohloli oa matla.OEA e boetse e eketsa polelo ea liphatsa tsa lefutso tse amehang ho mafura a acid oxidation, e leng ho eketsang tšebeliso ea matla le ho chesa mafura.
Ka kakaretso, mokhoa oa ts'ebetso oa OEA o kenyelletsa tšebelisano ea eona le li-receptor tse itseng 'meleng, haholo-holo PPAR-α, ho laola tekano ea matla, takatso ea lijo le metabolism ea lipid.Ka ho kenya li-receptor tsena tšebetsong, OEA e ka khothaletsa ho khora, ho ntlafatsa lipolysis, le ho ba le litlamorao tse khahlanong le ho ruruha.
●Litlhahiso tsa litekanyetso:
Ha ho tluoa tabeng ea litekanyetso tsa OEA, ho bohlokoa ho hlokomela hore lipatlisiso tse pharaletseng ho batho li ntse li tsoela pele.Leha ho le joalo, ho ipapisitsoe le liphuputso tse teng le bopaki ba nalane, litekanyetso tse sebetsang tsa letsatsi le letsatsi bakeng sa OEA li hloka ho qala ka litekanyetso tse nyane.
Ho bohlokoa ho buisana le setsebi sa tlhokomelo ea bophelo pele u qala tlatsetso efe kapa efe e ncha, ho kenyeletsoa OEA.Ba ka fana ka likeletso tsa motho ka mong ho latela litlhoko tsa hau tse ikhethileng le boemo ba bophelo bo botle, ho u thusa ho fumana litekanyetso tse nepahetseng bakeng sa boemo ba hau bo ikhethang.
●Litlamorao le Tšireletseho:
Le hoja ka kakaretso OEA e nkoa e sireletsehile bakeng sa tšebeliso, ho bohlokoa ho ela hloko litla-morao tse ka bang teng:
1.Mathata a ka mpeng: Maemong a mang, tlatsetso ea OEA e ka baka bohloko bo bobebe ba mala, joalo ka ho nyekeloa ke pelo kapa ho teneha ke mala.Hangata phello ena e itšetlehile ka litekanyetso 'me e fokotseha ha nako e ntse e ea.
2.Litšebelisano le Lithethefatsi: OEA e ka sebelisana le meriana e itseng, ho kenyeletsoa le e sebelisetsoang ho laola khatello ea mali kapa taolo ea k'holeseterole.Ka hona, ho bohlokoa ho tsebisa mofani oa hao oa tlhokomelo ea bophelo ka li-supplement leha e le life tseo u li noang ho qoba tšebelisano efe kapa efe e ka bang teng ea lithethefatsi.
3.Maemo a Allergic: Joalo ka tlatsetso efe kapa efe, batho ba bang ba kanna ba ba le kutloelo-bohloko kapa ba hana ho OEA.Haeba u e-ba le lintho tse ling tse bohloko tse kang lekhopho, ho hlohlona, kapa ho hema ka thata, khaotsa ho e sebelisa 'me u ee ngakeng hang-hang.
P: Ho nka nako e kae ho fumana melemo ea Oleoylethanolamide?
A: Nako e hlokahalang ho fumana melemo ea Oleoylethanolamide e ka fapana ho ea ka motho ka mong.Le hoja batho ba bang ba ka lemoha ntlafatso ea ho ruruha le bohloko ka potlako, ho ka nka nako e telele hore ba bang ba utloe liphello tsena.Ho bohlokoa ho lumellana le ho nka Oleoylethanolamide le ho latela litekanyetso tse khothalletsoang.
P: Nka fumana li-supplement tsa Oleoylethanolamide hokae?
A: Li-supplement tsa Oleoylethanolamide li ka fumanoa mabenkeleng a lijo tsa bophelo bo botle, li-pharmacy le barekisi ba marang-rang.Ha u reka li-supplement, etsa bonnete ba hore u khetha lihlahisoa ho tsoa ho li-brand tse tsebahalang tse khomarelang litekanyetso tsa boleng 'me li entse liteko tsa batho ba bang.
Boitlhotlhollo: Sengoliloeng sena ke sa merero ea tlhahisoleseling feela mme ha sea lokela ho nkuoa e le keletso ea bongaka.Kamehla buisana le setsebi sa tlhokomelo ea bophelo pele u sebelisa li-supplement kapa ho fetola mokhoa oa hau oa tlhokomelo ea bophelo.
Nako ea poso: Jul-24-2023
