Salidroside ke Eng 'me E ka U Thusa Joang?

Salidroside e boetse e tsejoa e le (4-hydroxy-phenyl) -β-D-glucopyranoside, e tsejoang hape e le salidroside le rhodiola extract. E ka ntšoa ho Rhodiola rosea kapa ea etsoa ka maiketsetso. Salidroside ke antioxidant ea tlhaho e sireletsang lisele tsa methapo ka ho senya ROS le ho thibela apoptosis ea lisele.

Rhodiola rosea ke semela sa perennial herbaceous se holang haholo libakeng tse nang le serame se phahameng, se omeletseng, anoxia, mahlaseli a matla a ultraviolet, le phapang e kholo ea mocheso lipakeng tsa mots'eare le bosiu sebakeng sa bophahamo ba limithara tse 1,600 ho isa ho tse 4,000. E na le matla a ho ikamahanya le maemo a tikoloho le matla.

Salidroside - Antioxidant

Salidroside ke antioxidant ea tlhaho e ka senyang mefuta ea oksijene e sebetsang (ROS), e thibela apoptosis, le ho sireletsa lisele tsa methapo. E ka ntlafatsa matla a ts'ireletso ea antioxidant ea letlalo ka ho kenya tšebetsong li-enzyme tsa intracellular antioxidant, joalo ka superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), joalo-joalo.

Intracellular calcium overload ke e 'ngoe ea lisosa tse kholo tsa neuronal apoptosis. Rhodiola rosea extract le salidroside e ka fokotsa ho eketseha ha maemo a khalsiamo a intracellular a bakoang ke khatello ea oxidative le ho sireletsa lisele tsa cortical tsa motho ho tloha glutamate. le apoptosis e bakoang ke hydrogen peroxide. Salidroside e ka thibela lipopolysaccharide-induced microglial activation, e thibela tlhahiso ea NO, e thibela mosebetsi oa inducible nitric oxide synthase (iNOS), le ho fokotsa TNF-α le IL-1β. , maemo a IL-6.

Salidroside e thibela NADPH oxidase 2/ROS/mitogen-activated protein kinase (MAPK) le regulator ea karabelo ea ntshetsopele le tšenyo ea DNA 1 (REDD1)/mammalian target of rapamycin (mTOR)/p70 ribosome Protheine S6 kinase signaling pathway activate the AMP-based protein kinase / silent information regulator 1, RAS homologous gene setho sa lelapa A/MAPK le PI3K/Akt litsela tsa lipontšo.

Melemo ea Salidroside

1. Phello ea mekhoa e 'meli ea ho laola: Rhodiola rosea e bokella lintlha tsohle tse ntle' meleng 'me e na le mekhoa e' meli ea ho laola phello ea ho etsa mefokolo le ho fokotsa ho feteletseng. Ka ho laola mesebetsi ea tsamaiso ea methapo, tsamaiso ea endocrine le tsamaiso ea metabolic, tsoekere ea mali, lipids ea mali, khatello ea mali le mesebetsi ea pelo le ea cerebrovascular e ka khutlisetsoa maemong a tloaelehileng.

2. Ho laola ka katleho tsamaiso ea methapo: ka katleho ho felisa tsitsipano ea batho, ho leka-lekanya tsamaiso ea methapo e bohareng, ho ntlafatsa boroko le ho teneha, thabo kapa ho tepella maikutlong; ntlafatsa tlhokomelo le ho ntlafatsa mohopolo. Hlakola boko, fokotsa litekanyetso tsa liphoso, ntlafatsa mosebetsi le katleho ea ho ithuta, le ho thibela lefu la Alzheimer.

3. Khahlanong le mokhathala: Rhodiola rosea e na le phello ea cardiotonic, e ka eketsang nako ea mesebetsi e tloaelehileng ea boko le 'mele le ho atolosa matla a mojaro a methapo ea boko le mesifa ea' mele. E na le phello e kholo ho thibela le ho phekola lefu la mokhathala le ho boloka matla a matla le matla ka nako e telele.

4. Anti-radiation le anti-tumor: Salidroside e ka eketsa ka katleho lebelo la phetoho ea T lymphocyte le mosebetsi oa phagocytes, ho matlafatsa sesole sa 'mele, ho thibela ho hōla ha hlahala, ho eketsa lisele tse tšoeu tsa mali, ho hanela mahlaseli a microwave, le ho phekola bakuli ba kankere ka mor'a radiotherapy le tse ling. E na le phello e ntle haholo ea ho thusa batho ba fokolang 'meleng ka mor'a ho kula.

5. Anti-hypoxia: Rhodiola rosea e ka fokotsa tekanyo ea ’mele ea ho sebelisa oksijene ka kakaretso, ea ntlafatsa ho mamella ha boko bokong ba hypoxia, ’me ka nako e tšoanang ea eketsa matla a ho tsamaisa oksijene ea mali, ea eketsa matla a ’mele a ho hanyetsa maloetse, ’me ea hlaphoheloa kapele lisele tse kulang. .

6. Phello ho mesifa e boreleli ea motho: Asma e bakoa ke ho hohla ha mesifa e boreleli. Rhodiola rosea e khona ho imolla mesifa e boreleli le ho laola ho sisinyeha ha mesifa ea mala. E na le litlamorao tse hlakileng ho asthma, bronchitis, phlegm, pipitlelano, joalo-joalo.

7. Phello ho ramatiki ea ramatiki: Ramatiki e bakoa ke lintho tse tharo tse mpe tsa moea, serame le mongobo. Palo e kholo ea liteko tsa meriana e pakile hore Rhodiola rosea e ka leleka moea, ea hanela serame, le ho felisa bohloko. Haholo-holo e na le liphello tse totobetseng ho ruruha ha manonyeletso. Ho ruruha le phello e thibelang.

8. Anti-botsofali: Rhodiola rosea e ka liehisa botsofali ba lisele, ea eketsa mosebetsi oa SOD 'meleng,' me ea thibela ho thehoa ha intracellular lipofuscin le mefuta ea oksijene e sebetsang. Ntlafatsa metabolism ea lisele le synthesis le ho ntlafatsa matla a lisele. Ho phaella moo, e boetse e na le liphello tsa botle le tlhokomelo ea letlalo.

Salidroside & Skin Care Field

Lefapheng la tlhokomelo ea letlalo, salidroside e ka hanela tšenyo ea ultraviolet le ho tlosa li-radicals tsa mahala tse hlahisoang ke mitochondria. Litlamorao tsa eona tsa antioxidant le anti-inflammatory li ka ntlafatsa boemo ba letlalo, tsa fokotsa masoba, 'me tsa etsa hore letlalo le shebahale le le le le lenyane.

Rhodiola rosea e ka fokotsa ts'ebetso ea acid phosphatase le lihlahisoa tsa ho qetela tsa ho bola tsa lipid peroxide (LPO) ka ho eketsa ts'ebetso ea li-enzyme tse amanang le antioxidant (SOD superoxide dismutase, GSH-Px glutathione peroxidase le CAT) le litaba tsa MDA, ka hona li matlafatsa bokhoni ba 'mele. ho qhekella li-radicals tsa mahala, ho fokotsa tekanyo ea peroxidation ea biofilm, le ho sireletsa lisele tsa 'mele le lisele ho tsoa tšenyo ea mahala.

Thibela ho phophoma ha letlalo

Salidroside e ka fokotsa ho senyeha ha matrix a extracellular joalo ka collagen le ho khothaletsa kholo ea fibroblasts, ka hona e matlafatsa letlalo, e liehisa ho hlaha ha makhopho a letlalo, le ho fihlela sepheo sa ho hanela ho thunya ha foto.

Ho soeufala

Salidroside e ka fokotsa motsoako oa melanin ka ho thibela ts'ebetso ea tyrosinase. Tyrosinase ke enzyme ea bohlokoa bakeng sa motsoako oa melanin. Salidroside e ka tlama tyrosinase mme ea fokotsa ts'ebetso ea eona, ka hona e fokotsa tlhahiso ea melanin.

Salidroside e ka boela ea thibela motsoako oa melanin ka ho laola litsela tsa lipontšo tsa melanocyte, tse kang tsela ea MITF ea ho bontša. MITF ke ntlha ea bohlokoa ea ho ngoloa ho melanocyte, e laolang polelo ea li-enzyme tse amanang le melanin tse kang tyrosinase. Salidroside e ka fokotsa polelo ea MITF, kahoo e fokotsa motsoako oa melanin.

Anti-inflammatory

Salidroside e ka fokotsa karabelo ea ho ruruha e bakoang ke mahlaseli a ultraviolet, ho lokisa lisele tsa letlalo tse senyehileng, le ho khothaletsa nchafatso ea letlalo le ho lokisoa.

Boemo ba hona joale ba tlhahiso ea salidroside

1) Haholo-holo itšetlehe ka ho ntšoa ha limela

Rhodiola rosea ke thepa e tala ea salidroside. Joalo ka mofuta oa semela sa herbaceous se sa feleng, Rhodiola rosea e hola haholo libakeng tse nang le serame se phahameng, anoxia, ho omella le phapang e kholo ea mocheso lipakeng tsa mots'eare le bosiu sebakeng sa bophahamo ba limithara tse 1600-4000. Ke se seng sa limela tse hlaha tsa sehlabeng. China ke e 'ngoe ea libaka tse ka sehloohong tse hlahisang Rhodiola rosea lefatšeng, empa mekhoa ea ho phela ea Rhodiola rosea e ikhethile haholo. Hase feela hore ho thata ho lema ka mokhoa oa maiketsetso, empa lihlahisoa tsa mefuta e sa tšoaneng ea hlaha li tlaase haholo. Hajoale, lekhalo la selemo le selemo la tlhokeho ea Rhodiola rosea le ka holimo ho lithane tse 2,200.

2) Kemiso ea lik'hemik'hale le ho belisoa ha likokoana-hloko

Ka lebaka la lihlahisoa tse tlaase le litšenyehelo tse phahameng tsa tlhahiso ea limela, ntle le mekhoa ea tlhaho ea tlhaho, mekhoa ea tlhahiso ea salidroside e boetse e kenyelletsa mekhoa ea ho kopanya lik'hemik'hale, mekhoa ea ho belisoa ha likokoana-hloko, joalo-joalo Har'a bona, ha theknoloji e ntse e tsoela pele ho hōla, ho belisoa ha likokoana-hloko ho fetohile ntho e tloaelehileng. tsela ea theknoloji bakeng sa lipatlisiso le nts'etsopele le tlhahiso ea salidroside. Hajoale, Suzhou Mailun e fihletse liphetho tsa lipatlisiso le nts'etsopele mme e fihletse kholo ea indasteri.

Mahlaseli ke karolo e ke keng ea qojoa ea bophelo ba rona ba letsatsi le letsatsi 'me e sebelisoa khafetsa tlhahlobong ea bongaka le kalafo. Leha ho le joalo, tšenyo e bakoang ke mahlaseli liseleng tsa motho le liseleng e ke ke ea hlokomolohuoa. Ka hona, ho fumana lisebelisoa tse sireletsang mahlaseli a kotsi tse sebetsang hantle, tse nang le chefo e tlase kapa tse seng chefo esale e le sebaka sa lipatlisiso.

Suzhou Myland Nutraceuticals Inc. ke moetsi ea ngolisitsoeng ke FDA ea fanang ka phofo ea Salidroside ea boleng bo holimo le bo hloekileng.

Suzhou Myland re ikemiselitse ho fana ka lihlahisoa tsa boleng bo holimo ka litheko tse ntle. Salidroside phofo ea rona e lekoa ka matla bakeng sa bohloeki le matla, ho netefatsa hore o fumana tlatsetso ea boleng bo phahameng eo u ka e tšepang. Hore na o batla ho ts'ehetsa bophelo bo botle ba cellular, ho matlafatsa sesole sa hau sa 'mele kapa ho ntlafatsa bophelo bo botle ka kakaretso, phofo ea rona ea Salidroside ke khetho e phethahetseng.

Ka boiphihlelo ba lilemo tse 30 'me e khannoa ke thekenoloji e phahameng le maano a R&D a ntlafalitsoeng haholo, Suzhou Myland e thehile lihlahisoa tse ngata tsa tlholisano mme e fetohile tlatsetso e ncha ea mahlale a bophelo, khamphani ea ho kopanya moetlo le lits'ebeletso tsa tlhahiso.

Ntle le moo, Suzhou Myland le eona ke moetsi ea ngolisitsoeng ke FDA. Lisebelisoa tsa R&D tsa k'hamphani, lisebelisoa tsa tlhahiso, le lisebelisoa tsa tlhahlobo ke tsa sejoale-joale ebile li na le mesebetsi e mengata, 'me li ka hlahisa lik'hemik'hale ho tloha ho limiligrama ho isa ho lithane ka tekanyo,' me li lumellana le litekanyetso tsa ISO 9001 le litlhaloso tsa tlhahiso ea GMP.