Salidroside ke Eng 'me e ka u thusa joang?

Salidroside e boetse e tsejoa e le (4-hydroxy-phenyl)-β-D-glucopyranoside, e tsejoang hape e le salidroside le rhodiola extract. E ka ntšoa ho Rhodiola rosea kapa ea etsoa ka maiketsetso. Salidroside ke antioxidant ea tlhaho e sireletsang lisele tsa methapo ka ho tlosa ROS le ho thibela apoptosis ea sele.

Rhodiola rosea ke semela sa dimela se melang ka nako e telele se melang haholo-holo dibakeng tse nang le serame se phahameng, komello, anoxia, mahlaseli a matla a ultraviolet, le dipharologanyo tse kgolo tsa mocheso pakeng tsa motsheare le bosiu bophahamong ba dimithara tse 1,600 ho isa ho tse 4,000. E na le bokgoni bo matla ba ho ikamahanya le tikoloho le matla.

Salidroside--Sebolaya-oxidant

Salidroside ke antioxidant ea tlhaho e ka senyang mefuta ea oksijene e arabelang (ROS), ea thibela apoptosis, le ho sireletsa lisele tsa methapo. E ka ntlafatsa bokhoni ba ho itšireletsa khahlanong le antioxidant ea letlalo ka ho kenya tšebetsong litsamaiso tsa li-enzyme tsa antioxidant tse ka hare ho sele, tse kang superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), jj.

Ho feteletsa ha calcium ka hare ho sele ke e 'ngoe ea lisosa tse ka sehloohong tsa apoptosis ea methapo ea kutlo. Rhodiola rosea extract le salidroside li ka fokotsa keketseho ea maemo a calcium a mahala a ka hare ho sele a bakoang ke khatello ea oxidative le ho sireletsa lisele tsa cortical tsa motho ho glutamate. le apoptosis e bakoang ke hydrogen peroxide. Salidroside e ka thibela ts'ebetso ea microglial e bakoang ke lipopolysaccharide, ea thibela tlhahiso ea NO, ea thibela ts'ebetso ea inducible nitric oxide synthase (iNOS), le ho fokotsa maemo a TNF-α le IL-1β. , IL-6.

Salidroside e thibela NADPH oxidase 2/ROS/mitogen-activated protein kinase (MAPK) le regulator ea karabelo ea nts'etsopele le tšenyo ea DNA 1 (REDD1)/sepheo sa mammalian sa ribosome ea rapamycin (mTOR)/p70. Tsela ea ho supa ea protheine S6 kinase e kenya tšebetsong AMP-dependent protein kinase/silent information regulator 1, RAS homologous gene family method A/MAPK le PI3K/Akt signaling.

Melemo ea Salidroside

1. Phello ea taolo ea litsela tse peli: Rhodiola rosea e kopanya lintho tsohle tse ntle 'meleng 'me e na le phello ea taolo ea litsela tse peli ea ho lokisa mefokolo le ho fokotsa ho feteletseng. Ka ho laola mesebetsi ea tsamaiso ea methapo, tsamaiso ea endocrine le tsamaiso ea metabolism, tsoekere ea mali, mafura a mali, khatello ea mali le mesebetsi ea pelo le methapo ea mali le ea boko li ka khutlisetsoa maemong a tloaelehileng.

2. Taolo e sebetsang ea tsamaiso ea methapo: ho felisa khatello ea maikutlo ea batho ka katleho, ho leka-lekanya tsamaiso ea methapo e bohareng, ho ntlafatsa boroko le ho teneha, thabo kapa khatello ea maikutlo; ho ntlafatsa tlhokomelo le ho ntlafatsa mohopolo. Ho khatholla boko, ho fokotsa sekhahla sa liphoso, ho ntlafatsa katleho ea mosebetsi le thuto, le ho thibela lefu la Alzheimer.

3. Ho thibela mokhathala: Rhodiola rosea e na le phello ea ho fokotsa khatello ea pelo, e ka eketsang nako ea mesebetsi e tloaelehileng ea boko le 'mele le ho atolosa bokhoni ba ho jara methapo ea boko le mesifa ea 'mele. E na le phello e kholo ho thibeleng le ho phekoleng mokhathala le ho boloka matla a matla le matla ka nako e telele.

4. Thibelo ea mahlaseli le ho thibela hlahala: Salidroside e ka eketsa ka katleho sekhahla sa phetoho ea li-lymphocyte tsa T le ts'ebetso ea li-phagocyte, ea ntlafatsa sesole sa 'mele, ea thibela kholo ea hlahala, ea eketsa lisele tse tšoeu tsa mali, ea hanela mahlaseli a microwave, le ho phekola bakuli ba kankere kamora kalafo ea mahlaseli le tse ling. E na le phello e ntle haholo ea tsosoloso bakeng sa ba fokolang 'meleng kamora ho kula.

5. Thibelo ea hypoxia: Rhodiola rosea e ka fokotsa sekhahla sa tšebeliso ea oksijene 'meleng ka kakaretso, ea ntlafatsa mamello ea boko ho hypoxia, 'me ka nako e ts'oanang ea eketsa bokhoni ba mali ba ho jara oksijene, ea eketsa ho hanyetsa mafu 'meleng,' me ea khutlisa lisele tse kulang kapele.

6. Tšusumetso mesifa e boreleli ea motho: Asma e bakoa ke ho thibana ha mesifa e boreleli. Rhodiola rosea e ka imolla ho thibana ha mesifa e boreleli ka katleho le ho laola motsamao oa mesifa e boreleli ea mala. E na le litlamorao tse totobetseng ho asma, bronchitis, phlegm, pipitlelano, jj.

7. Phello ho ramatiki: Ramatiki e bakoa ke lintho tse tharo tse mpe tsa moea, serame le mongobo. Liteko tse ngata tsa bongaka li pakile hore Rhodiola rosea e ka leleka moea, ea hanela serame le ho felisa bohloko. Haholo-holo e na le liphello tse totobetseng ho ruruha ha manonyeletso. Ho ruruha le phello ea thibelo.

8. Thibelo ea botsofali: Rhodiola rosea e ka liehisa botsofali ba lisele, ea eketsa ts'ebetso ea SOD 'meleng,' me ea thibela ho thehoa ha lipofuscin ka hare ho sele le mefuta ea oksijene e arabelang. E ntlafatsa metabolism ea sele le tlhahiso ea eona le ho ntlafatsa matla a sele. Ho feta moo, e boetse e na le botle le litlamorao tsa tlhokomelo ea letlalo.

Tšimo ea Tlhokomelo ea Salidroside le Letlalo

Lefapheng la tlhokomelo ea letlalo, salidroside e ka hanela tšenyo ea mahlaseli a kotsi a letsatsi le ho tlosa li-free radical tse hlahisoang ke mitochondria. Litlamorao tsa eona tsa antioxidant le anti-inflammatory li ka ntlafatsa boemo ba letlalo, tsa fokotsa matheba, 'me tsa etsa hore letlalo le shebahale le le lecha.

Rhodiola rosea e ka fokotsa ts'ebetso ea acid phosphatase le lihlahisoa tsa ho qetela tsa ho bola ha lipid peroxide (LPO) ka ho eketsa ts'ebetso ea li-enzyme tse amanang le antioxidant (SOD superoxide dismutase, GSH-Px glutathione peroxidase le CAT) le litaba tsa MDA, ka hona e ntlafatsa bokhoni ba 'mele ba ho senya li-free radicals, e fokotsa tekanyo ea peroxidation ea biofilms, le ho sireletsa lisele le lisele tsa' mele tšenyong ea li-free radicals.

Thibela ho nka lifoto tsa letlalo

Salidroside e ka fokotsa ho senyeha ha matrix ea kantle ho letlalo joalo ka collagen le ho khothaletsa kholo ea li-fibroblast, ka hona e eketsa ho tenyetseha ha letlalo, e liehisa ho hlaha ha matheba a letlalo, le ho fihlela sepheo sa ho hanela ho tsofala ha letlalo ka photoaging.

Ho soeufatsa

Salidroside e ka fokotsa tlhahiso ea melanin ka ho thibela ts'ebetso ea tyrosinase. Tyrosinase ke enzyme ea bohlokoa bakeng sa tlhahiso ea melanin. Salidroside e ka tlama ho tyrosinase mme ea fokotsa ts'ebetso ea eona, ka hona ea fokotsa tlhahiso ea melanin.

Salidroside e ka boela ea thibela tlhahiso ea melanin ka ho laola litsela tsa lipontšo ho melanocyte, joalo ka tsela ea lipontšo ea MITF. MITF ke ntlha ea bohlokoa ea ho ngola li-melanocyte, e laolang tlhahiso ea li-enzyme tse amanang le tlhahiso ea melanin tse kang tyrosinase. Salidroside e ka fokotsa tlhahiso ea MITF, ka hona ea fokotsa tlhahiso ea melanin.

Anti-ho ruruha

Salidroside e ka fokotsa karabelo ea ho ruruha e bakoang ke mahlaseli a ultraviolet, ea lokisa lisele tsa letlalo tse senyehileng, le ho khothaletsa tsosoloso le tokiso ea letlalo.

Boemo ba hona joale ba tlhahiso ea salidroside

1) Itšetlehile haholo ka ho ntša limela

Rhodiola rosea ke thepa e tala ea salidroside. Jwalo ka mofuta oa semela sa litlama se sa feleng, Rhodiola rosea e hola haholo libakeng tse nang le serame se phahameng, anoxia, komello le phapang e kholo ea mocheso pakeng tsa motšehare le bosiu bophahamong ba limithara tse 1600-4000. Ke e 'ngoe ea limela tsa naha tse sabaletseng. Chaena ke e 'ngoe ea libaka tse ka sehloohong tse hlahisang Rhodiola rosea lefatšeng, empa mekhoa ea ho phela ea Rhodiola rosea e ikhetha haholo. Hase feela hore ho thata ho lema ka maiketsetso, empa chai ea mefuta ea naha e tlase haholo. Hona joale, sekheo sa tlhoko ea selemo le selemo sa Rhodiola rosea se holimo ho fihla ho lithane tse 2,200.

2) Ho kopanngoa ha lik'hemik'hale le ho belisoa ha baeloji

Ka lebaka la dikahare tse tlase le ditjeo tse phahameng tsa tlhahiso dimeleng, ho phaella mekgweng ya tlhaho ya ho ntsha dimela, mekgwa ya tlhahiso ya salidroside e boetse e kenyeletsa mekgwa ya ho kopanya dikhemikhale, mekgwa ya ho bela baeloji, jj. Har'a tsona, ha theknoloji e ntse e tswela pele ho hola, ho bela baeloji e se e le tsela e ka sehloohong ya theknoloji bakeng sa dipatlisiso le ntshetsopele le tlhahiso ya salidroside. Hona jwale, Suzhou Mailun e fihletse diphetho tsa dipatlisiso le ntshetsopele mme e fihletse kgolo ya diindasteri.

Mahlasedi ke karolo e ke keng ea qojoa ea bophelo ba rona ba letsatsi le letsatsi 'me a sebelisoa khafetsa ho hlahlobeng le kalafong ea bongaka. Leha ho le joalo, tšenyo e bakoang ke mahlaseli liseleng tsa batho e ke ke ea hlokomolohuoa. Ka hona, ho fumana lisebelisoa tse sireletsang mahlaseli tse sebetsang hantle, tse se nang chefo e ngata kapa tse se nang chefo esale e le sebaka se seholo sa lipatlisiso.

Suzhou Myland Nutraceuticals Inc. ke moetsi ea ngolisitsoeng ke FDA ea fanang ka phofo ea Salidroside ea boleng bo holimo le e hloekileng haholo.

Ho Suzhou Myland re ikemiselitse ho fana ka lihlahisoa tsa boleng bo holimo ka litheko tse ntle ka ho fetisisa. Phofo ea rona ea Salidroside e lekoa ka thata bakeng sa bohloeki le matla, ho netefatsa hore u fumana tlatsetso ea boleng bo holimo eo u ka e tšepang. Hore na u batla ho tšehetsa bophelo bo botle ba lisele, ho matlafatsa sesole sa hau sa 'mele kapa ho ntlafatsa bophelo bo botle ka kakaretso, phofo ea rona ea Salidroside ke khetho e phethahetseng.

Ka boiphihlelo ba lilemo tse 30 le ho khannoa ke theknoloji e phahameng le maano a R&D a ntlafalitsoeng haholo, Suzhou Myland e hlahisitse mefuta e fapaneng ea lihlahisoa tse hlōlisanang 'me e fetohile khamphani e ncha ea tlatsetso ea mahlale a bophelo, tlhahiso ea lintho tse ikhethileng le lits'ebeletso tsa tlhahiso.

Ho phaella moo, Suzhou Myland le yona ke moetsi ya ngodisitsweng ke FDA. Mehlodi ya R&D ya khamphani, dibaka tsa tlhahiso, le disebediswa tsa tlhahlobo ke tsa sejwalejwale mme di sebetsa ka bongata, mme di ka hlahisa dikhemikhale ho tloha ho dimiligrama ho isa ho ditone ka boholo, mme di latela maemo a ISO 9001 le ditlhaloso tsa tlhahiso GMP.