Galantamine Hydrobromide phofo moetsi CAS No.: 1953-04-4 98% bohloeki min.bakeng sa lisebelisoa tsa tlatsetso
Lihlahisoa tsa lihlahisoa
| Lebitso la sehlahisoa | Galantamine Hydrobromide |
| Lebitso le leng | galanthamine hydrobromide; Galantamine HBr; Galanthamine HBr;(4aS,6R,8aS)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-Benzofuro[3a,3,2-ef][2]benzazepin- 6-ol, Hydrobromide |
| Nomoro ea CAS. | 1953-04-4 |
| Mokhoa oa limolek'hule | C17H21NO3.HBr |
| Boima ba molek'hule | 368.27 |
| Bohloeki | 98.0% |
| Ponahalo | phofo e tshweu ho isa ho bosweu |
| Ho paka | 1kg / mokotla 10kgs, 25kgs / moqomo |
| Kopo | lithethefatsi tsa nootropic |
Kenyelletso ea sehlahisoa
Galantamine hydrobromide ke mofuta oa benzozepine e nkiloeng ho bulbs le lipalesa tsa narcissus, osmanthus, kapa canna.Hape ke inhibitor ea molomo ea cholinesterase.Joaloka ligand ea nicotinic acetylcholine receptor, e 'nile ea sebelisoa haholo ho ntlafatsa ts'ebetso ea methapo ea kutlo.Karolo ea eona ke ho thibela acetylcholinesterase ka tlholisano le ka mokhoa o feto-fetohang, ka hona e eketsa bongata ba acetylcholine.
Ha e kenngoa maling, galanthamine hydrobromide e kenngoa habonolo likarolong tsohle tsa 'mele, ho akarelletsa le boko.E tlama ho nicotinic acetylcholine receptor, e bakang liphetoho tsa conformational le ho eketsa ho lokolloa ha acetylcholine.E boetse e sebetsa ka ho hlōlisana le ho khutlisetsa morao liphello tsa li-inhibitors tsa cholinesterase.Ka ho thibela cholinesterase, e thibela ho bola ha acetylcholine, kahoo e eketsa boemo le nako ea neurotransmitter ena e matla.Galanthamine e boetse e ntlafatsa bokhoni ba ho ithuta le ho hopola, e thibela ho ruruha ha boko le ho boloka maemo a phahameng a li-neurotransmitters ka ho boloka botšepehi ba li-neurone le li-synapses.
Sebopeho
(1) Phello e 'ngoe ea bohlokoa ea galanthamine hydrobromide ntlafatsong ea mohopolo ke bokhoni ba eona ba ho ntlafatsa ts'ebetso ea mohopolo.E eketsa lebelo la ho theha mohopolo mme e ntlafatsa ho boloka lintlha le lintlha.
(2) Bokhoni ba ho ithuta bo ntlafatsoa ka ho eketsa polasetiki ea synaptic le neuroplasticity.Galanthamine hydrobromide e ama ka ho toba kapa ka tsela e sa tobang neuroplasticity.E susumetsa polasetiki ea synaptic ka ho kenya tšebetsong microglia le astrocyte.
(3) E thusa ho robala le ho eketsa phomolo.Galanthamine e ka eketsa bothata ba ho robala ka ho tsosa boroko bo potlakileng ba mahlo, kahoo e ntlafatsa boleng ba boroko.
(4) Ntlafatsa tšireletso ea antioxidant, Galantamine e fana ka tšireletso ea antioxidant ho loantša khatello ea oxidative e bakoang ke li-radicals tsa mahala.E ka sireletsa lisele tsa boko ho senyeha ha oxidative ho boloka ts'ebetso e nepahetseng ea boko.
Lisebelisoa
Galantamine hydrobromide e ka ntlafatsa mohopolo, kelello, le bokhoni ba ho etsa mesebetsi ea letsatsi le letsatsi.E sebetsa ka ho khutlisetsa botsitso ba lintho tse itseng tsa tlhaho (li-neurotransmitters) bokong.
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