N-Boc-O-Benzyl-D-serine moetsi oa phofo CAS No.: 47173-80-8 98% bohloeki min. bakeng sa ba Mahareng
Lihlahisoa tsa lihlahisoa
| Lebitso la sehlahisoa | N-Boc-O-Benzyl-D-serine |
| Lebitso le leng | N-Boc-O-benzyl-D-serine; Boc-O-benzyl-D-serine; O-Benzyl-N-(tert-butoxycarbonyl)-D-serine; Boc-(R) -2-amino-3-benzyloxypropionic acid; Boc-D-Ser(Bzl)-OH;Nat.-Boc-O-benzyl-D-serine; N-tert-butyloxycarbonyl-O-benzyl-D-serine; Nalpha-t-butoxycarbonyl-O-benzyl-D-serine; |
| Nomoro ea CAS. | 47173-80-8 |
| Mokhoa oa limolek'hule | C15H21NO5 |
| Boima ba molek'hule | 295.33 |
| Bohloeki | 98% |
| Ho paka | 1kg / mokotla; 25kg / moropa |
| Kopo | Batsehare |
Kenyelletso ea sehlahisoa
N-Boc-O-Benzyl-D-serine ke motsoako o fumaneng tlhokomelo e kholo lefapheng la chemistry ea tlhaho le lipatlisiso tsa meriana. Motsoako ona, oo hape o tsejoang e le Boc-D-serine, o tsoa ho amino acid D-serine mme o sebelisoa haholo ha ho etsoa litlhare tse fapaneng le limolek'hule tsa bioactive. N-Boc-O-Benzyl-D-serine ke phofo ea kristale e tšoeu ho isa ho bosoeu e qhibilihang hanyenyane metsing 'me e qhibiliha ka har'a metsoako ea tlhaho e kang methanol le ethanol. Ke motsoako oa D-serine, e leng amino acid e seng proteinogenic e bapalang karolo ea bohlokoa tsamaisong ea methapo e bohareng e le co-agonist ea N-methyl-D-aspartate (NMDA) receptor. Lihlopha tsa N-Boc (tert-butoxycarbonyl) le O-Benzyl ka har'a motsoako li sebetsa e le lihlopha tse sireletsang, tse lumellang hore ho khethoe ka mokhoa o ikhethileng oa amino acid nakong ea motsoako oa lik'hemik'hale.N-Boc-O-Benzyl-D-serine e sebelisoa haholo-holo e le moaho oa motsoako oa li-peptide le li-peptidomimetics. Li-peptide ke liketane tse khutšoane tsa li-amino acid tse bapalang likarolo tse fapaneng ts'ebetsong ea tlhaho mme li na le thahasello e kholo ho sibolloeng le nts'etsopele ea lithethefatsi. Ka ho kenyelletsa N-Boc-O-Benzyl-D-serine tatellanong ea peptide, litsebi tsa k'hemistri li ka fetola thepa le mesebetsi ea li-peptide tse hlahisitsoeng, tsa e etsa sesebelisoa sa bohlokoa moralong oa li-agent tse ncha tsa meriana. Ho feta moo, N-Boc-O-Benzyl-D-serine e sebelisoa ha ho etsoa li-intermediate tsa meriana le metsoako e sebetsang ea meriana (APIs). Reactivity ea eona e feto-fetohang le ho lumellana le mekhoa e fapaneng ea lik'hemik'hale e etsa hore e be karolo e batloang ka har'a motsoako oa limolek'hule tse rarahaneng tse nang le matla a phekolo.
Sebopeho
(1) Bohloeki bo phahameng: N-Boc-O-Benzyl-D-serine e ka fumana lihlahisoa tse hloekileng ka ho hloekisa mekhoa ea tlhahiso. Bohloeki bo phahameng bo bolela bioavailability e betere le ho fokotseha ho hoholo ha maikutlo.
(2) Tšireletseho: Tšireletseho e phahameng, liketso tse seng kae tse mpe.
(3) Botsitso: N-Boc-O-Benzyl-D-serine e na le botsitso bo botle 'me e ka boloka mosebetsi oa eona le phello tlas'a maemo a fapaneng le maemo a polokelo.
Lisebelisoa
Ho kenyelletsoa ha N-Boc-O-Benzyl-D-serine limolek'huleng tsa lithethefatsi ho bontšitsoe ho fana ka thepa e lakatsehang ea pharmacokinetic le pharmacodynamic. Peptidomimetics e nkiloeng ho N-Boc-O-Benzyl-D-serine e bontšitse botsitso bo ntlafetseng, bioavailability, le sepheo sa sepheo, e leng se etsang hore e be batho ba tšepisang bakeng sa phekolo ea maloetse a fapa-fapaneng, ho akarelletsa le mofetše, mafu a tšoaetsanoang le mafu a methapo ea kutlo. ho fetola ka mokhoa o ikhethileng karolo ea N-Boc-O-Benzyl-D-serine e lumella ho hlophisoa hantle ha batho ba sebelisang lithethefatsi, ho ntlafatsa ts'ebetso ea bona ea ts'ebetso le polokeho ea bona.
