NRC CAS No.: 23111-00-4 98.0% bohloeki min.bakeng sa Anti-botsofali
Lihlahisoa tsa lihlahisoa
| Lebitso la sehlahisoa | Nicotinamide Riboside Chloride |
| Lebitso le leng | NicotinamideB-DRibosideChloride(WX900111); NicotinamideRiboside.Cl;Nicotimideribosidechloride; Pyridinium,3-(aminocarbonyl) -1-β-D-ribofuranosyl-,chloride(1:1); 3-carbamoyl-1- ((2R,3R,4S,5R) -3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-iumchloride; 3-Carbamoyl-1-(β-D-ribofuranosyl)pyridiniumchloride; 3-Carbamoyl-1-beta-D-ribofuranosylpyridiniumchloride |
| Nomoro ea CAS. | 23111-00-4 |
| Mokhoa oa limolek'hule | C11H15ClN2O5 |
| Boima ba molek'hule | 290.7 |
| Bohloeki | 98.0% |
| Ponahalo | Phofo e tšoeu ho isa ho e tšoeu |
| Kopo | Tlatsetso ea Lijo tse tala |
Kenyelletso ea sehlahisoa
Nicotinamide Riboside Chloride ke biomolecule le e nkiloeng ho vithamine B3 e ka monngoang le ho sebelisoa ke 'mele oa motho ho ba selelekela sa coenzyme NAD+ (nicotinamide adenine dinucleotide).Coenzyme NAD+ e bapala likarolo tse ngata tsa bohlokoa 'meleng oa motho, ho kenyelletsa metabolism ea matla a cellular, tokiso ea DNA, le apoptosis ea lisele.
Litlamorao tsa biological tsa Nicotinamide Riboside Chloride li ithutoe haholo.E ka khothaletsa ts'ebetso ea mitochondrial, ka hona e ntlafatsa metabolism ea matla a cellular.Keketseho ena ea metabolism ea matla e ka ba molemo bakeng sa bophelo bo botle ba pelo, mamello ea mesifa le mathata a metabolism.Ntle le moo, Nicotinamide Riboside Chloride ho lumeloa hore e khothaletsa tokiso ea DNA le apoptosis ea lisele, ka hona e thusa ho thibela ho hlaha ha mofetše le mafu a mang.
Nicotinamide Riboside Chloride e ka boela ea ntlafatsa ts'ebetso ea sesole sa 'mele sa motho, ea thusa ho hanela tšoaetso ea vaerase le baktheria.Liphuputso li bonts'itse hore Nicotinamide Riboside Chloride e ka khothaletsa ts'ebetso ea lisele tse ling tsa 'mele tsa ho itšireletsa mafung, ho kenyeletsoa lisele tse bolaeang tsa tlhaho le lisele tsa CD8 + T.Lisele tsena li phetha karolo ea bohlokoa ho loantšeng tšoaetso le lihlahala.
Ka kakaretso, lipatlisiso ka Nicotinamide Riboside Chloride e ntse e le methating ea eona ea pele mme ho hlokahala lithuto tse ling tsa bongaka ho paka ts'ebetso le polokeho ea eona.Leha ho le joalo, litlamorao tsa eona tsa tlhaho li ithutoe haholo mme ho lumeloa hore e na le melemo e mengata ea bophelo bo botle le kalafo.
Sebopeho
(1) Selelekela sa NAD +: Nicotinamide Riboside Chloride ke selelekela sa nicotinamide adenine dinucleotide (NAD+), coenzyme e bapalang karolo ea bohlokoa lits'ebetsong tse ngata tsa tlhaho, ho kenyeletsoa matla a metabolism ea cellular, tokiso ea DNA, le pontšo ea lisele.Ka ho fana ka mohloli oa NAD +, Nicotinamide Riboside Chloride e ka thusa ho ntlafatsa lits'ebetso tsena le ho khothaletsa bophelo bo botle ka kakaretso.
(2) Liphello tse khahlanong le botsofali: Nicotinamide Riboside Chloride e bontšitsoe hore e na le liphello tse ka 'nang tsa e-ba khahlanong le botsofali, haholo-holo mabapi le mosebetsi oa mitochondrial.Boithuto bo fana ka maikutlo a hore tlatsetso ea Nicotinamide Riboside Chloride e ka eketsa maemo a NAD + le ho ntlafatsa biogenesis ea mitochondrial, e ka thusang ho loants'a ho fokotseha ho amanang le botsofali ts'ebetsong ea cellular.
(3) Liphello tsa Neuroprotective: Nicotinamide Riboside Chloride e boetse e bontšitsoe hore e na le liphello tsa neuroprotective, 'me lithuto tse ling li fana ka maikutlo a hore e ka thusa ho ntlafatsa ts'ebetso ea kelello le ho sireletsa khahlanong le mafu a methapo a kang Alzheimer's le Parkinson.
(4) Litla-morao tse fokolang: Nicotinamide Riboside Chloride e fumanoe e sireletsehile ebile e mamelloa hantle, e nang le litla-morao tse seng kae tse tlalehiloeng.E boetse e etsahala ka tlhaho lijong tse ling, joalo ka lebese le tomoso, e ts'ehetsa boemo ba eona ba polokeho.
Lisebelisoa
Nicotinamide Riboside Chloride ke biomolecule e ithutoang haholo e nkiloeng ho vithamine B3 mme e sebetsa e le selelekela sa coenzyme NAD+ 'meleng, e bapala karolo ea bohlokoa ea tlhaho.Hajoale, libaka tsa mantlha tsa ts'ebeliso ea Nicotinamide Riboside Chloride li kenyelletsa mafu a pelo le cerebrovascular, mafu a neurodegenerative, mafu a metabolic le anti-botsofali.Mohlala, Nicotinamide Riboside Chloride e ka thusa ho ntlafatsa mafu a amanang le metabolism a kang lefu la pelo le cerebrovascular, lefu la tsoekere le botenya ka ho eketsa metabolism ea matla a cellular le ho ntlafatsa ts'ebetso ea mitochondrial.Ho feta moo, Nicotinamide Riboside Chloride ho lumeloa hore e na le monyetla oa ho loants'a mafu a neurodegenerative le anti-botsofali.Boithuto bo bonts'itse hore Nicotinamide Riboside Chloride e ka ntlafatsa bokhoni ba kelello le ts'ebetso ea tsamaiso ea methapo ho likhoto tse tsofetseng.
Ntle le moo, Nicotinamide Riboside Chloride e 'nile ea sebelisoa ho phekola mathata a metabolism ea uracil, e leng bothata bo sa tloaelehang ba tlhaho ba tlhaho.
Ha lipatlisiso tsa Nicotinamide Riboside Chloride li ntse li tsoela pele ho teba, menyetla ea ts'ebeliso ea eona e ntse e eketseha le ho feta.Mohlala, Nicotinamide Riboside Chloride e ka sebelisoa e le mothusi oa lithethefatsi ho phekola mofetše.Lipatlisiso li bonts'itse hore Nicotinamide Riboside Chloride e ka khothaletsa tokiso ea DNA le apoptosis ea lisele, ka hona e thusa ho thibela ho hlaha ha mofets'e le mafu a mang.Ntle le moo, Nicotinamide Riboside Chloride e ka ntlafatsa ts'ebetso ea sesole sa 'mele sa motho, e thusa ho hanela tšoaetso ea vaerase le baktheria.Lisebelisoa tsena tse ka bang teng li etsa Nicotinamide Riboside Chloride e 'ngoe ea libaka tsa morao-rao tsa lipatlisiso.
Ho feta moo, mokhoa oa ho kopanya lik'hemik'hale oa Nicotinamide Riboside Chloride o lula o ntlafala, 'me litšenyehelo tsa eona tsa tlhahiso lia fokotseha, e leng se fanang ka menyetla e mengata ea ts'ebeliso ea eona lefapheng la bongaka.Ka hona, Nicotinamide Riboside Chloride e lebelletsoe ho fetoha biomolecule e nang le tebello e pharaletseng ea ts'ebeliso nakong e tlang.
