Moetsi oa phofo ea Oleoylethanolamide (OEA) Nomoro ea CAS: 111-58-0 98%,85% bohloeki ba metsotso bakeng sa metsoako ea tlatsetso
Liparamente tsa Sehlahisoa
| Lebitso la sehlahisoa | Oleoyl ethanolamide |
| Lebitso le leng | N-oleoyl ethanolamine; N-(2-hydroxyethyl)-,(Z)-9-Octadecenamide |
| Nomoro ea CAS | 111-58-0 |
| Foromo ea limolek'hule | C20H39NO2 |
| Boima ba limolek'hule | 325.53 |
| Bohloeki | 98.0% ，85.0% |
| Ponahalo | Phofo e ntle ea kristale e tšoeu |
| Ho paka | 1kg/mokotla, 25kg/moropa |
| Kopo | Phomolo ea bohloko, e thibelang ho ruruha |
Selelekela sa sehlahisoa
Oleoylethanolamide ke motsoako oa bobeli oa amide o entsoeng ka lipophilic oleic acid le hydrophilic ethanolamine. Oleoylethanolamide hape ke molek'hule ea lipid e hlahang ka tlhaho liseleng tse ling tsa liphoofolo le limela. E fumaneha haholo liseleng tsa liphoofolo le limela tse kang phofo ea cocoa, soya le linate, empa litaba tsa eona li tlase haholo. Ke feela ha tikoloho ea kantle e fetoha kapa lijo li hlohlelletsoa, lisele tsa lisele tsa 'mele Ke ka nako eo feela ntho ena e tla hlahisoa.
Mochesong oa kamore, Oleoylethanolamide ke solid e tšoeu e nang le ntlha ea ho qhibiliha ea hoo e ka bang 50°C. E qhibiliha habonolo ka har'a metsoako e tahang e kang methanol le ethanol, e qhibiliha habonolo ka har'a metsoako e seng ea polar e kang n-hexane le ether, 'me ha e qhibilihe ka metsing. OEA ke molek'hule e nang le amphiphilic e sebelisoang ka tloaelo e le surfactant le sesepa indastering ea lik'hemik'hale. Leha ho le joalo, lipatlisiso tse ling li fumane hore OEA e ka sebetsa e le molek'hule ea lipontšo tsa lipid ka har'a motsoako oa mala le boko 'me ea bontša letoto la mesebetsi ea baeloji' meleng, ho kenyeletsoa: ho laola takatso ea lijo, ho ntlafatsa metabolism ea lipid, ho ntlafatsa mohopolo le kutloisiso le mesebetsi e meng. Har'a tsona, mesebetsi ea Oleoylethanolamide ea ho laola takatso ea lijo le ho ntlafatsa metabolism ea lipid e fumane tlhokomelo e kholo.
Oleoylethanolamide e ka laola homeostasis ea lijo le matla ka ho kenya tšebetsong receptor-α e sebetsang ka peroxisome proliferator. Ho phaella moo, Oleoylethanolamide e bontša mesebetsi e meng e amanang le bophelo bo botle, ho kenyeletsoa le ho fetola ts'ebetso ea converter tseleng ea lipontšo tsa lysosomal-to-nuclear e amanang le taolo ea nako e telele le ho sireletsa methapo e laolang boitšoaro ba khatello ea maikutlo. Lipatlisiso li boetse li bontša hore Oleoylethanolamide e ka ba le litlamorao tsa ts'ireletso ea methapo. Mehlaleng ea liphoofolo, e fumanoe e fokotsa tšenyo e bakoang ke stroke le kotsi ea boko e bohloko. Tšusumetso ea taolo ea Oleoylethanolamide e amahanngoa le ho tlama ha eona ho PPARα, e fokotsehang ka retinoid X receptor (RXR) mme e e kenya tšebetsong e le ntlha e matla ea transcription e amehang homeostasis ea matla e kopaneng, metabolism ea lipid, autophagy, le ho ruruha.
Tšobotsi
(1) Bohloeki bo phahameng: OEA e ka fumana dihlahiswa tse hlwekileng haholo ka mekgwa ya tlhahiso ya ho hlwekisa. Bohloeki bo phahameng bo bolela ho fumaneha ha dihlahiswa hantle le dikarabelo tse fokolang tse mpe.
(2) Polokeho: OEA e pakiloe e bolokehile bakeng sa 'mele oa motho.
(3) Botsitso: OEA e na le botsitso bo botle mme e ka boloka ts'ebetso le phello ea eona tlas'a maemo a fapaneng a tikoloho le maemo a polokelo.
(4) Ho monya habonolo: OEA e ka monngoa kapele ke 'mele oa motho 'me ea ajoa liseleng le lithong tse fapaneng.
Likopo
Oleoylethanolamide ke lipid ea tlhaho ea ethanolamide e sebelisoang e le moralo oa lijo le taolo ea boima ba 'mele mefuteng e fapaneng ea liphoofolo tse nang le lesapo la mokokotlo. Ke metabolite ea oleic acid e entsoeng ka maleng a manyenyane a motho. Oleylethanolamide (OEA) ke molek'hule e laolang metabolism ea lipid le homeostasis ea matla. E khomarela li-receptor tsa PPAR Alpha 'me e thusa ho laola lintlha tse' nè: tlala, mafura a 'mele, k'holeseterole le boima. PPAR Alpha e emela alpha ea receptor e sebetsang ka peroxide proliferator, 'me lipid e sebetsang ka bioactive amide oleoylethanolamide (OEA) e na le mefuta e fapaneng ea thepa ea homeostatic e ikhethang, ho kenyeletsoa le ts'ebetso ea ho thibela ho ruruha, phetoho ea karabelo ea' mele ea ho itšireletsa mafung, le litlamorao tsa antioxidant.
