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Moetsi oa phofo ea Coluracetam CAS No.: 135463-81-9 99% bohloeki min. bakeng sa lisebelisoa tsa tlatsetso

Tlhaloso e Khutšoanyane:

Coluracetam ke setho sa lelapa la racetam la metsoako ea nootropic hape e tsejoa e le MKC-231. E entsoe ke Kobe Pharmaceutical Company e Japane ka sepheo sa ho phekola AD le mathata a kelello.


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Coluracetam

Lebitso le leng

MKC-231;

2-oxo-N-(5,6,7,8-tetrahydro-2,3-dimethyl-furo[2,3-b]quinolin-4-yl) -1-pyrrolidineacetamide

Nomoro ea CAS.

135463-81-9

Mokhoa oa limolek'hule

Setšoantšo sa C19H23N3O3

Boima ba molek'hule

341.4

Bohloeki

99.0%

Ponahalo

Phofo e tšoeu

Kopo

Tlatsetso ea Lijo tse tala

Kenyelletso ea sehlahisoa

Coluracetam, setho sa lelapa la racemate la metsoako ea nootropic, eo hape e tsejoang e le MKC-231, ke motsoako oa nootropic o nang le liphello tse matlafatsang tsebo le tsa neuroprotective. Coluracetam e sebetsa ka ho fetola tsamaiso ea cholinergic. Ho nahanoa hore e eketsa maemo a acetylcholine, neurotransmitter ea bohlokoa bokong e amanang haholo le mesebetsi ea ho ithuta le ea mohopolo. Coluracetam e etsa sena ka ho eketsa palo le mosebetsi oa li-transporters tsa choline, kahoo li ntlafatsa ho lokolloa ha acetylcholine le ho ntlafatsa pontšo pakeng tsa li-neurons. Liphuputso tse ling tsa pele tsa liteko le tsa liphoofolo li fana ka maikutlo a hore Coluracetam e na le liphello tse ka 'nang tsa e-ba teng tsa neuroprotective le ho ntlafatsa kutloisiso. Liphuputso tse ling li fumane hore Coluracetam e na le phello e itseng ea ntlafatso ho holofala ha mohopolo mefuteng ea AD.

Sebopeho

(1) Bohloeki bo phahameng: Coluracetam e lokiselitsoe ho sebelisoa mekhoa e tsoetseng pele ea ho ntša le ho etsa tlhahiso ho netefatsa bohloeki bo phahameng. Bohloeki bona bo phahameng bo thusa ho ntlafatsa bioavailability le ho fokotsa ho hlaha ha karabelo e mpe.
(2) Tšireletseho: Coluracetam e nkoa e sireletsehile bakeng sa batho. Palo e kholo ea lithuto li pakile hore e na le chefo e tlase le litlamorao tse fokolang ka har'a mefuta e khothalletsoang ea litekanyetso.
(3) Botsitso: Litokisetso tsa Coluracetam li bontša botsitso bo babatsehang 'me li ka boloka mosebetsi oa tsona le katleho tlas'a maemo a sa tšoaneng le maemo a polokelo. Botsitso bona bo netefatsa ts'ebetso e tsitsitseng le e ka tšeptjoang ka nako e telele.

Lisebelisoa

Coluracetam hajoale e sebelisoa lits'ebetsong tse fapaneng mme e bonts'a tšepiso e kholo ea bokamoso. Haholo-holo e sebelisoa e le tlatsetso ea lijo tse matlafatsang kutloisiso 'me e batloa ke batho ba batlang ho ntlafatsa mohopolo, ho tsepamisa mohopolo le bokhoni ba ho ithuta. Bokhoni ba motsoako oa ho fetola tsamaiso ea cholinergic ho nahanoa hore bo tlatsetsa liphellong tsa eona tse matlafatsang tsebo. Ho phaella moo, lipatlisiso li bontša hore Coluracetam e ka 'na ea e-ba le lisebelisoa tsa neuroprotective tse ka thusang ho thibela ho fokotseha ho amanang le lilemo le ho tšehetsa bophelo bo botle ba boko.


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