YDL223C (HBT1) moetsi oa phofo CAS No.: 489408-02-8 99% bohloeki min. bakeng sa lisebelisoa tsa tlatsetso
Video ea Sehlahisoa
Lihlahisoa tsa lihlahisoa
| Lebitso la sehlahisoa | HBT1 |
| Lebitso le leng | YDL223C |
| Nomoro ea CAS. | 489408-02-8 |
| Mokhoa oa limolek'hule | Setšoantšo sa C16H17F3N4O2S |
| Boima ba molek'hule | 386.40 |
| Bohloeki | 99.0% |
| Ponahalo | Bosehla bo kganyang bo tiileng |
| Ho paka | 1kg ka mokotla 25kg ka moropa |
| Kopo | lithethefatsi tsa nootropic |
Kenyelletso ea sehlahisoa
HBT1 e tlamella sebakeng se tlamang ligand sa α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA-R) ka mokhoa o itšetlehileng ka glutamate. Sena se bolela hore HBT1 ke molek'hule e khonang feela ho tlama sebakeng se itseng ho protheine ea AMPA-R ha glutamate e le teng, 'me tlamo ena e thusa ho laola tšebetso ea protheine. Li-receptor tsa AMPA li hlahisoa ho pholletsa le tsamaiso ea methapo e bohareng 'me li phetha karolo ea bohlokoa puisanong ea neuronal, ts'ebetso ea kutlo, ho ithuta, mohopolo le polasetiki ea synaptic. Li-receptor tsa AMPA ke tsona tse kenyang letsoho ho pharalletseng ha methapo ea kutlo, li kenella ka potlako, ka potlako, li nyahamisa maikutlo ho li-synapse tse ngata, 'me li kenya letsoho likarabelong tsa pele tsa glutamate libakeng tsa synaptic. Hangata li-receptor tsa AMPA li hlahisoa ka kopanelo le li-receptor tsa NMDA ho li-synapse, 'me hammoho li khothaletsa lits'ebetso tsa polasetiki tsa synaptic tse amehang ho ithuteng, mohopolong, ho excitotoxicity le neuroprotection. Boko-derived neurotrophic factor (BDNF) ke neurotrophic factor e phethang karolo ea bohlokoa tlhokomelong le katolosong ea methapo ea kutlo 'me e na le liphello tse matla le tse ngata ho atang, ho khetholla, ho phela le lefu la lisele tsa neuronal le tse seng tsa neuronal. , modulator ea li-neurotransmitter e tlatsetsang ho polasetiki ea neuronal thutong le mohopolong. Ka hona, e bohlokoa bakeng sa bophelo bo botle le boiketlo ba tsamaiso ea methapo.
Sebopeho
(1) Bohloeki bo phahameng: HBT1 e ka fumana lihlahisoa tse hloekileng ka ho hloekisa mekhoa ea tlhahiso. Bohloeki bo phahameng bo bolela bioavailability e betere le ho fokotseha ho hoholo ha maikutlo.
(2) Tšireletseho: HBT1 e pakiloe e sireletsehile bakeng sa ’mele oa motho.
(3) Botsitso: HBT1 e na le botsitso bo botle mme e ka boloka ts'ebetso ea eona le phello tlas'a maemo a fapaneng le maemo a polokelo.
Lisebelisoa
HBT1 ke nova AMPA receptor enhancer e nang le agonism e tlase, e susumetsang tlhahiso ea boko-derived neurotrophic factor (BDNF) mme e na le litlamorao tse fokolang tsa agonistic ho li-neurone tsa mantlha. HBT1 e tlamella sebakeng se tlamang ligand sa AMPA-R ka mokhoa o itšetlehileng ka glutamate. Ka kopanelo, ba khothaletsa lits'ebetso tsa polasetiki tsa synaptic tse amehang ho ithuteng, ho hopola, ho hlasimoloha le ts'ireletso ea methapo. E ka ntlafatsa bokhoni ba boko ba kelello le mohopolo, le ho ntlafatsa bokhoni ba batho ba ho ithuta. Hangata e kenngoa lijong tsa letsatsi le leng le le leng ka mokhoa oa ho ja lijo.
