Moetsi oa phofo oa PRL-8-53 Nomoro ea CAS: 51352-87-5 Bohloeki ba 98% bonyane bakeng sa metsoako ea tlatsetso
Liparamente tsa Sehlahisoa
| Lebitso la sehlahisoa | PRL-8-53 |
| Lebitso le leng | Methyl 3-(2-(benzyl(Methyl)aMino)ethyl)benzoate hydrochloride；Benzoic acid, 3-[2-[methyl(phenylmethyl)amino]ethyl]-, methyl ester, hydrochloride (1:1)；Methyl 3-{2-[benzyl(methyl)amino]ethyl}benzoate hydrochloride (1:1) |
| Nomoro ea CAS | 51352-87-5 |
| Foromo ea limolek'hule | C18H22ClNO2 |
| Boima ba limolek'hule | 319.83 |
| Bohloeki | 98.0% |
| Ponahalo | Phofo e tšoeu |
| Ho paka | 1 kg ka mokotlana 25kg/moropa |
| Kopo | nootropic |
Selelekela sa sehlahisoa
PRL-8-53, e tsejoang hape e le methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate, ke motsoako oa maiketsetso oa nootropic o nahanoang hore o ntlafatsa phetiso ea cholinergic le ho Laola maemo a dopamine bokong. Boitšoaro bona bo kenya letsoho liphellong tsa eona tse ka ntlafatsang tsebo, ka hona bo ntlafatsa ho thehoa ha mohopolo, ho boloka le ho khutlisa. Lithuto tse ngata ho liphoofolo le batho li tlalehile liphetho tse ntle bakeng sa thepa ea eona e ntlafatsang mohopolo. Phuputsong ea teko e laoloang ke placebo, batho ba fumaneng tekanyo e le 'ngoe ea PRL-8-53 ba bontšitse bokhoni bo betere ba ho hopola mantsoe le ho khutlisa ha ba bapisoa le sehlopha sa placebo. Liphuputso tsena li ile tsa tsosa thahasello le lipatlisiso tse ling mabapi le bokhoni ba motsoako. Phuputso e 'ngoe ho likhoto e bontšitse hore ho fa PRL-8-53 ho ntlafalitse haholo bokhoni ba bona ba ho ithuta mosebetsing oa maze oa metsi. Likhoto tse phekoloang ka PRL-8-53 li ile tsa khona ho fumana sethala se patiloeng ka katleho ho feta li-control, li bontša bokhoni ba motsoako e le ntho e ntlafatsang mohopolo.
Tšobotsi
(1) Bohloeki bo phahameng: PRL-8-53 e ka fumana dihlahiswa tse hlwekileng haholo ka mekgwa ya tlhahiso ya ho hlwekisa. Bohloeki bo phahameng bo bolela ho fumaneha ha dihlahiswa hantle le dikarabelo tse fokolang tse mpe.
(2) Polokeho: Polokeho e phahameng, dikarabelo tse fokolang tse mpe, ha ho dikarabelo tse mpe tse totobetseng.
(3) Botsitso: PRL-8-53 e na le botsitso bo botle mme e ka boloka ts'ebetso le phello ea eona tlas'a maemo a fapaneng a tikoloho le maemo a polokelo.
Likopo
Jwalo ka mofuta o motjha wa tlatsetso ya ntlafatso ya kelello, PRL-8-53 e ntlafatsa mohopolo wa nako e kgutshwane le mohopolo wa ho sebetsa, ha ka nako e ts'oanang e ntlafatsa bokgoni ba ho ithuta le lebelo la ho fumana bokgoni, e thusa ho ntlafatsa bokgoni ba ho ithuta le ho sebetsa hantle. Diphuputso di bontsha hore PRL-8-53 e ka kgothaletsa kgolo le tsosoloso ya di-neuron bokong. PRL-8-53 e ka eketsa lebelo leo boko bo sebetsanang le tlhahisoleseding ka lona, e dumella batho ho phethela mesebetsi le ho etsa diqeto kapele. Le hoja e bapiswa le metswako e meng ya nootropic Leha ho le jwalo, diphuputso mabapi le PRL-8-53 di lekanyeditswe, empa diphuputso tse teng di bontsha bokgoni ba yona ba ho ntlafatsa mohopolo le bokgoni ba ho nahana.
