Motsoako oa 7P moetsi oa phofo CAS No.: 1890208-58-8 99% bohloeki min.bakeng sa lisebelisoa tsa tlatsetso
Lihlahisoa tsa lihlahisoa
| Lebitso la sehlahisoa | Motsoako oa 7P |
| Lebitso le leng | Compound7P;2- [(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide; 2-(N-(2-methoxyphenyl)-4-methylphenylsulfonamido)-N-(4-methoxypyridin-3-yl)acetamide |
| Nomoro ea CAS. | 1890208-58-8 |
| Mokhoa oa limolek'hule | C22H23N3O5S |
| Boima ba molek'hule | 441.51 |
| Bohloeki | 99.0% |
| Ponahalo | Phofo e tšoeu |
| Kopo | Nootropic |
Kenyelletso ea sehlahisoa
Compound 7p e bontšitsoe ho susumetsa kholo ea li-axon tsa GAP-43-positive ka mohlala oa phoofolo ea kotsi ea methapo ea optic, e fana ka maikutlo a hore ts'ebetso ea neurite outgrowth ea motsoako oa 7p in vitro e fetolela ho tsosoa ha axon regeneration ka vivo.Motsoako oa 7P phofo ke phofo e tšoeu ho ea ho e tšoeu e hlahisoang e le motsoako oa tandem bakeng sa ho tsebahatsa li-inhibitors tse peli tse sebetsang ka thromboxane receptor antagonist.Ka 'nete, motsoako oa 7p o bonts'a khetho ea prostaglandin I2 synthase (PTGIS, CYP8A1) holim'a thromboxane synthase (CYP5A1).Nootropic ke ntho efe kapa efe e thusang ho ntlafatsa ts'ebetso ea boko, ho kenyelletsa mohopolo, mohopolo, maikutlo, esita le bohlale.Li ka tloha ho lihlopha tse itseng tsa lijo kapa lintho ho ea ho metsoako e entsoeng ke motho e etselitsoeng ka ho khetheha ho thusa boko bo sebetsang le melemo e meng.Nootropic compound 7P phofo e khothalletsa ho tsoa ha li-axon tse ntle tsa Gap-43, kahoo li susumetsa ho tsosolosoa ha axonal ka vivo.7p ea boleng bo holimo e etselitsoe ho ntlafatsa tšebelisano, ho ntlafatsa maikutlo le ho thusa ho loantša mokhathala.E boetse e thibela oxidation ea boko le ho thusa ho loantša tšenyo ea boko e bakoang ke ho noa joala.
Lisebelisoa
Li-neurons tsamaisong ea batho ba baholo ba methapo ea kutlo (CNS) li hlōleha ho tsosolosa li-axon ka mor'a kotsi, eo ka karolo e 'ngoe e hlalosang ho fola ha ts'ebetso ho bakuli ba nang le ts'oaetso le mafu a neurodegenerative.Compound 7p, e ntlafatsang kholo ea methapo ea kutlo ho li-neuron tsa mantlha tse hlahisitsoeng ho hippocampus, cerebral cortex le retina, 'me e susumetsa ho nchafatsoa ha methapo ea kutlo ka mohlala oa phoofolo ea kotsi ea methapo ea kutlo.E boetse e eketsa tšebelisano, e phekola tšenyo ea boko e amanang le joala, 'me e thibela oxidation ho potoloha boko.E boetse e thusa ho ntlafatsa maikutlo a motho le ho loantša mokhathala.Ho feta moo komporo ea 7P e bonts'itse ts'ebetso e phahameng ka ho fetesisa khahlano le lihlahala tsa popelo ka ho ntlafatsa sebopeho sa microstructure ka mokhoa o itšetlehileng ka lethal dose.Ntlafatso e eketsehileng ea komporo ea 7p le ho hlakisoa ha mochini oo e bakang ho nchafatsoa ha axon ka vivo e tla fana ka mabaka a utloahalang bakeng sa boiteko ba kamoso ba ho matlafatsa maano a kalafo.
