Motsoako oa 7P moetsi oa phofo CAS No.: 1890208-58-8 99% bohloeki min. bakeng sa lisebelisoa tsa tlatsetso
Video ea Sehlahisoa
Lihlahisoa tsa lihlahisoa
| Lebitso la sehlahisoa | Motsoako oa 7P |
| Lebitso le leng | Compound7P;2- [(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide; 2-(N-(2-methoxyphenyl)-4-methylphenylsulfonamido)-N-(4-methoxypyridin-3-yl)acetamide |
| Nomoro ea CAS. | 1890208-58-8 |
| Mokhoa oa limolek'hule | C22H23N3O5S |
| Boima ba molek'hule | 441.51 |
| Bohloeki | 99.0% |
| Ponahalo | Phofo e tšoeu |
| Kopo | Nootropic |
Kenyelletso ea sehlahisoa
Compound 7P e bolela motsoako o itseng oa tlhaho o nang le liathomo tse supileng tsa carbon. Ka k'hemistri ea lintho tse phelang, carbon ke ntho ea bohlokoa hobane e ka theha maqhama a tsitsitseng le liathomo tse ling, ho akarelletsa le liathomo tsa carbon, ho etsa limolek'hule tse rarahaneng. Limolek'hule tsena li ka ba le thepa le mesebetsi e sa tšoaneng, 'me li etsa hore metsoako e entsoeng ka k'habone e be lintho tse ahang bophelo. Mefuteng ea liphoofolo tsa kotsi ea methapo ea optic, motsoako oa 7p o ile oa bontšoa ho etsa hore ho be le li-axon tse ntle tsa GAP-43, tse fanang ka maikutlo a hore mosebetsi oa ho hōla ha neurite oa motsoako oa 7p in vitro o fetolela ho tsosoa ha axonal ho tsosolosoa ha vivo. Motsoako oa 7P phofo ke phofo e tšoeu ho ea ho e tšoeu e hlahisoang e le motsoako oa tandem bakeng sa ho tsebahatsa li-inhibitors tse peli tse sebetsang ka thromboxane receptor antagonist. Ha e le hantle, motsoako oa 7p o bontšitse selectivity bakeng sa prostaglandin I2 synthase (PTGIS, CYP8A1) e amanang le thromboxane synthase (CYP5A1). Motsoako oa nootropic 7P phofo o khothalletsa ho hōla ha li-axon tsa Gap-43-positive, kahoo li susumetsa ho tsosolosoa ha axonal 'meleng. Complex 7p ea boleng bo holimo e etselitsoe ho ntlafatsa khokahanyo, ho ntlafatsa maikutlo le ho thusa ho loantša mokhathala. E boetse e thibela boko oxidation mme e thusa ho loantša tšenyo ea boko e bakoang ke ho noa joala.
Sebopeho
(1) Bohloeki bo phahameng: Compound 7P e ka fumana lihlahisoa tse phahameng tsa bohloeki ka mekhoa e hloekisitsoeng ea tlhahiso. Bohloeki bo phahameng bo bolela bioavailability e betere le ho fokotseha ho hoholo ha maikutlo.
(2) Tšireletseho: Compound 7P e pakiloe e sireletsehile bakeng sa 'mele oa motho.
(3) Botsitso: Compound 7P e na le botsitso bo botle 'me e ka boloka ts'ebetso ea eona le phello tlas'a maemo a fapaneng le maemo a polokelo.
Lisebelisoa
Compound 7p e ntlafatsa kholo ea methapo ea methapo ea methapo ea methapo ea methapo ea methapo e tsoang ho hippocampus, cerebral cortex le retina mme e etsa hore ho tsosolosoe ha methapo ea mahlo ho mefuta ea liphoofolo ea kotsi ea methapo ea mahlo. E boetse e ntlafatsa tšebelisano, e phekola tšenyo ea boko e amanang le joala, 'me e thibela oxidation ho potoloha boko. E boetse e thusa ho ntlafatsa maikutlo le ho loantša mokhathala.
