Nooglutyl phofo moetsi CAS No.: 112193-35-8 99.0% bohloeki min. bakeng sa lisebelisoa tsa tlatsetso
Lihlahisoa tsa lihlahisoa
| Lebitso la sehlahisoa | Nooglutyl |
| Lebitso le leng | Nooglutil; N- [(5-Hydroxy-3-pyridinyl)carbonyl]-L-glutamicacid;N- [(5-Hydroxypyridin-3-yl)carbonyl]-L-glutamicacid; ONK-10; L-GlutaMicacid,N- [(5-hydroxy-3-pyridinyl) carbonyl]-; N-(5-hydroxynicotinoyl) -L-glutamicacid |
| Nomoro ea CAS. | 112193-35-8 |
| Mokhoa oa limolek'hule | C11H12N2O6 |
| Boima ba molek'hule | 268.22 |
| Bohloeki | 99.0% |
| Ponahalo | Phofo e tšoeu kapa e batlang e le tšoeu |
| Kopo | Tlatsetso ea Lijo tse tala |
Kenyelletso ea sehlahisoa
Nooglutyl, ke motsoako oa maiketsetso oo e leng oa lelapa la racemate la nootropics. E ile ea qalisoa Russia ka bo-1980 'me esale e tsebahala har'a basebelisi ba batlang ntlafatso ea kelello. Nooglutyl e nkoa e le ts'ebetso ea ts'oaetso ea metabolism, e bolelang hore ho nahanoa hore e ntlafatsa ts'ebetso ea kelello ka ho eketsa tlhahiso ea matla le metabolism bokong. Ho nahanoa hore e ntlafatsa sebopeho sa mohopolo le ho boloka mohopolo ka ho khothaletsa ho lokolloa ha neurotransmitter acetylcholine bokong. Ka lebaka leo, basebelisi ba fumana ntlafatso ea ts'ebetso ea tlhahisoleseling, ho tsepamisa maikutlo ho ntlafalitsoeng, le ho hopola kapele.
Ho phaella moo, Nooglutyl ho nahanoa hore e khothalletsa ho lokolloa ha glutamate, neurotransmitter e tsosang takatso ea bohlokoa bakeng sa ho ntlafatsa ts'ebetso ea kelello. Ka ho eketsa maemo a glutamate, Nooglutyl e ntlafatsa metabolism ea matla a boko, kahoo e ntlafatsa ho falimeha, ho hlaka kelellong, le ts'ebetso ea kelello ka kakaretso. Litlamorao tse susumetsang tsa Nooglutyl ho li-receptor tsa glutamate li ka thusa ho ntlafatsa ho tsepamisa maikutlo le ho tsepamisa maikutlo. Ka ho fetola tsamaiso ea boko ea glutamate, nootropic ena e ka thusa batho ka bomong ho hlōla litšitiso le ho boloka tlhokomelo e tsitsitseng, kahoo ba eketsa tlhahiso le ts'ebetso mesebetsing e fapaneng.
Sebopeho
(1) Bohloeki bo phahameng: Nooglutyl e ka fumana lihlahisoa tse phahameng tsa bohloeki ka ho ntša tlhaho le mokhoa o motle oa tlhahiso. Bohloeki bo phahameng bo bolela bioavailability e betere le ho fokotseha ho hoholo ha maikutlo.
(2) Tšireletseho: Nooglutyl ke sehlahisoa sa tlhaho se bontšitsoeng hore se sireletsehile ho batho. Ka har'a mefuta ea litekanyetso, ha e na chefo kapa litla-morao.
(3) Botsitso: Nooglutyl e na le botsitso bo botle 'me e ka boloka mosebetsi le phello ea eona tlas'a maemo a fapaneng a tikoloho le polokelo.
(4) Ho bonolo ho monya: Nooglutyl e ka kenngoa ka potlako ke 'mele oa motho, ea kena ho potoloha ha mali ka pampiri ea mala,' me ea abela lisele le litho tse fapaneng.
Lisebelisoa
Nooglutyl ke setho sa lelapa la racemate mme o bontšitse tšepiso e kholo ho ntlafatsa ts'ebetso ea kelello le ho fana ka melemo ea nootropic. Bokhoni ba eona ba ho eketsa mohopolo, matla a kelello, ho tsepamisa mohopolo, le ho sireletsa khahlano le khatello ea oxidative bo e etsa khetho e khahlisang bakeng sa batho ba batlang ho ntlafatsa ts'ebetso ea kelello. Lipatlisiso li fana ka maikutlo a hore sebopeho se ikhethang sa lik'hemik'hale sa Nooglutyl se ka ba neuroprotective. Ho nahanoa hore e fokotsa khatello ea kelello ea oxidative, e thibela tšenyo ea lisele tsa boko e bakoang ke li-radicals tsa mahala, le ho thusa ho boloka le ho nchafatsa likhokahano tsa neuronal. Liphello tsena tse ka 'nang tsa e-ba teng tsa neuroprotective li etsa hore Nooglutyl e be khetho e thahasellisang bakeng sa batho ba amehileng ka ho fokotseha ho amanang le lilemo kapa lefu la methapo.
